Publications
2024
Davis, CN; Crump, RE; Sutherland, SA; Spencer, SEF; Corbella, A; Chansy, S; Lebuki, J; Miaka, EM; Rock, KS (2024) Comparison of stochastic and deterministic models for gambiense sleeping sickness at different spatial scales: A health area analysis in the DRC PLOS COMPUTATIONAL BIOLOGY 20 e1011993
Crump, RE; Aliee, M; Sutherland, SA; Huang, C; Crowley, EH; Spencer, SEF; Keeling, MJ; Shampa, C; Miaka, EM; Rock, KS (2024) Modelling timelines to elimination of sleeping sickness in the Democratic Republic of Congo, accounting for possible cryptic human and animal transmission PARASITES & VECTORS 17 332
Richardson, MJE (2024) Linear and nonlinear integrate-and-fire neurons driven by synaptic shot noise with reversal potentials PHYSICAL REVIEW E 109 24407
Asplin, P; Keeling, MJ; Mancy, R; Hill, EM (2024) Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation PLOS COMPUTATIONAL BIOLOGY 20 e1012096
Cant, S; Shanks, GD; Keeling, MJ; Penman, BS (2024) Extreme mortality during a historical measles outbreak on Rotuma is consistent with measles immunosuppression EPIDEMIOLOGY & INFECTION 152 e85
Davis, EL; Hollingsworth, TD; Keeling, MJ (2024) An analytically tractable, age-structured model of the impact of vector control on mosquito-transmitted infections PLOS COMPUTATIONAL BIOLOGY 20 e1011440
Vlachou, D; Veretennikova, M; Usselmann, L; Vasilyev, V; Ott, S; Bjarnason, GA; Dallmann, R; Levi, F; Rand, DA (2024) TimeTeller: A tool to probe the circadian clock as a multigene dynamical system PLOS COMPUTATIONAL BIOLOGY 20 e1011779
Asplin, P; Mancy, R; Finnie, T; Cumming, F; Keeling, MJ; Hill, EM (2024) Symptom propagation in respiratory pathogens of public health concern: a review of the evidence JOURNAL OF THE ROYAL SOCIETY INTERFACE 21 20240009
Moore, MP; Laager, M; Ribeca, P; Didelot, X (2024) KmerAperture: Retaining k-mer synteny for alignment-free extraction of core and accessory differences between bacterial genomes PLOS GENETICS 20 e1011184
Carson, J; Keeling, M; Wyllie, D; Ribeca, P; Didelot, X (2024) Inference of Infectious Disease Transmission through a Relaxed Bottleneck Using Multiple Genomes Per Host MOLECULAR BIOLOGY AND EVOLUTION 41 msad288
Rawlings, NN; Bailey, M; Craig, P; Courtenay, O (2024) Cutaneous leishmaniasis in British troops following jungle training in Belize: Cumulative incidence and potential risk practices PARASITE EPIDEMIOLOGY AND CONTROL 27 e00385
Eigentler, L; Sensi, M (2024) Delayed loss of stability of periodic travelling waves: Insights from the analysis of essential spectra JOURNAL OF THEORETICAL BIOLOGY 595 111945
Medina-Aguayo, FJ; Didelot, X; Everitt, R (2024) Speeding up Inference of Homologous Recombination in Bacteria BAYESIAN ANALYSIS 19 1245-1275
Bouros, I; Hill, EM; Keeling, MJ; Moore, S; Thompson, RN (2024) Prioritising older individuals for COVID-19 booster vaccination leads to optimal public health outcomes in a range of socio-economic settings PLOS COMPUTATIONAL BIOLOGY 20 e1012309
Burroughs, NJ; Leuridan, MLC (2024) Optimising the tumour elimination payoff in cancer therapy IET CONTROL THEORY AND APPLICATIONS 18 1621-1637
Doyle, NJ; Cumming, F; Thompson, RN; Tildesley, MJ (2024) When should lockdown be implemented? Devising cost-effective strategies for managing epidemics amid vaccine uncertainty PLOS COMPUTATIONAL BIOLOGY 20 e1012010
Nair, S; Barker, CR; Bird, M; Greig, DR; Collins, C; Painset, A; Chattaway, M; Pickard, D; Larkin, L; Gharbia, S; Didelot, X; Ribeca, P (2024) Presence of phage- plasmids in multiple serovars of Salmonella enterica MICROBIAL GENOMICS 10 1247
Moro, S; Spencer, SEF; Lester, DW; Nübling, F; Sommer, M; Costantini, G (2024) Molecular-Scale Imaging Enables Direct Visualization of Molecular Defects and Chain Structure of Conjugated Polymers ACS NANO 18 11655-11664
Keeling, MJ; Dyson, L (2024) A retrospective assessment of forecasting the peak of the SARS-CoV-2 Omicron BA.1 wave in England PLOS COMPUTATIONAL BIOLOGY 20 e1012452
Cartes, JA; Bonizzoni, P; Ciccolella, S; Della Vedova, G; Denti, L; Didelot, X; Monti, DC; Pirola, Y (2024) RecGraph: recombination-aware alignment of sequences to variation graphs BIOINFORMATICS 40 btae292
Fairbanks, EL; Daly, JM; Tildesley, MJ (2024) Modelling the Influence of Climate and Vector Control Interventions on Arbovirus Transmission VIRUSES-BASEL 16 1221
Vasconcelos, A et al. (2024) Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions? CLINICAL INFECTIOUS DISEASES 78 S83-S92
Reinhold, K; Eigentler, L; Kikuchi, DW (2024) Evolution of individual variation in a competitive trait: a theoretical analysis JOURNAL OF EVOLUTIONARY BIOLOGY 37 538-547
Roberts, GO; Rosenthal, JS (2024) Football group draw probabilities and corrections CANADIAN JOURNAL OF STATISTICS-REVUE CANADIENNE DE STATISTIQUE 52 659-677
Lambisia, AW; Murunga, N; Mutunga, M; Cheruiyot, R; Maina, G; Makori, TO; Nokes, DJ; Agoti, CN (2024) Temporal changes in the positivity rate of common enteric viruses among paediatric admissions in coastal Kenya, during the COVID-19 pandemic, 2019-2022 GUT PATHOGENS 16 2
Osman, R; Dema, E; David, A; Hughes, G; Field, N; Cole, M; Didelot, X; Saunders, J (2024) Understanding the potential role of whole genome sequencing (WGS) in managing patients with gonorrhoea: A systematic review of WGS use on human pathogens in individual patient care JOURNAL OF INFECTION 88 106168
Rosazza, T; Earl, C; Eigentler, L; Davidson, FA; Stanley-Wall, NR (2024) Reciprocal sharing of extracellular proteases and extracellular matrix molecules facilitates Bacillus subtilis biofilm formation MOLECULAR MICROBIOLOGY 122 184-200
Kay, RR; Lutton, JE; King, JS; Bretschneider, T (2024) Making cups and rings: the 'stalled-wave ' model for macropinocytosis BIOCHEMICAL SOCIETY TRANSACTIONS 52 1785-1794
Courson, J; Quoy, M; Timofeeva, Y; Manos, T (2024) An exploratory computational analysis in mice brain networks of widespread epileptic seizure onset locations along with potential strategies for effective intervention and propagation control FRONTIERS IN COMPUTATIONAL NEUROSCIENCE 18 1360009
Owuor, DC; Ngoi, JM; Nyasimi, FM; Murunga, N; Nyiro, JU; Chaves, SS; Nokes, DJ; Agoti, CN (2024) Local patterns of spread of influenza A H3N2 virus in coastal Kenya over a 1-year period revealed through virus sequence data SCIENTIFIC REPORTS 14 23426
Ogi-Gittins, I; Hart, WS; Song, J; Nash, RK; Polonsky, J; Cori, A; Hill, EM; Thompson, RN (2024) A simulation-based approach for estimating the time-dependent reproduction number from temporally aggregated disease incidence time series data EPIDEMICS 47 100773
Kendall, M; Ferretti, L; Wymant, C; Tsallis, D; Petrie, J; Di Francia, A; Di Lauro, F; Abeler-Dörner, L; Manley, H; Panovska-Griffiths, J; Ledda, A; Didelot, X; Fraser, C (2024) Drivers of epidemic dynamics in real time from daily digital COVID-19 measurements SCIENCE 385 eadm8103
Fotopoulou, ET; Jenkins, C; Barker, CR; Painset, A; Didelot, X; Simbo, A; Douglas, A; Godbole, G; Jorgensen, F; Gharbia, S; McLauchlin, J (2024) Genomic epidemiology of the clinically dominant clonal complex 1 in the Listeria monocytogenes population in the UK MICROBIAL GENOMICS 10 1155
Owuor, DC; de Laurent, ZR; Oketch, JW; Murunga, N; Otieno, JR; Nabakooza, G; Chaves, SS; Nokes, DJ; Agoti, CN (2024) Phylogeography and reassortment patterns of human influenza A viruses in sub-Saharan Africa SCIENTIFIC REPORTS 14 18987
MacDonald, JC; Gulbudak, H; Beechler, B; Gorsich, EE; Gubbins, S; Pérez-Martin, E; Jolles, AE (2024) Within-Host Viral Growth and Immune Response Rates Predict Foot-and-Mouth Disease Virus Transmission Dynamics for African Buffalo AMERICAN NATURALIST 204 133-146
Fielder, H; Beale, T; Jeger, MJ; Oliver, G; Parnell, S; Szyniszewska, AM; Taylor, P; Cunniffe, NJ (2024) A Synoptic Review of Plant Disease Epidemics and Outbreaks Published in 2022 PHYTOPATHOLOGY 114 1717-1732
Li, H et al. (2024) Centralized industrialization of pork in Europe and America contributes to the global spread of Salmonella enterica NATURE FOOD 5
Nyiro, JU et al. (2024) The cost of care for children hospitalized with respiratory syncytial virus (RSV) associated lower respiratory infection in Kenya BMC PUBLIC HEALTH 24 2410
Rock, KS; Chapman, LAC; Dobson, AP; Adams, ER; Hollingsworth, TD (2024) The Hidden Hand of Asymptomatic Infection Hinders Control of Neglected Tropical Diseases: A Modeling Analysis CLINICAL INFECTIOUS DISEASES 78 S175-S182
Pratt, HG; Ma, L; Dziadowicz, SA; Ott, S; Whalley, T; Szomolay, B; Eubank, TD; Hu, GQ; Boone, BA (2024) Analysis of single nuclear chromatin accessibility reveals unique myeloid populations in human pancreatic ductal adenocarcinoma CLINICAL AND TRANSLATIONAL MEDICINE 14 e1595
Croft, W; Pounds, R; Jeevan, D; Singh, K; Balega, J; Sundar, S; Williams, A; Ganesan, R; Kehoe, S; Ott, S; Zuo, J; Yap, J; Moss, P (2024) The chromatin landscape of high-grade serous ovarian cancer metastasis identifies regulatory drivers in post-chemotherapy residual tumour cells COMMUNICATIONS BIOLOGY 7 1211
Carvalho, BM; Maia, C; Courtenay, O; Llabrés-Brustenga, A; Batista, M; Moirano, G; van Daalen, KR; Semenza, JC; Lowe, R (2024) A climatic suitability indicator to support Leishmania infantum surveillance in Europe: a modelling study LANCET REGIONAL HEALTH-EUROPE 43 100971
Katsamba, P; Butler, MD; Koens, L; Montenegro-Johnson, TD (2024) Slender phoretic loops and knots PHYSICAL REVIEW FLUIDS 9 54201
Nimmo, C; Ortiz, AT; Tan, CCS; Pang, J; Acman, M; Millard, J; Padayatchi, N; Grant, AD; O'Donnell, M; Pym, A; Brynildsrud, OB; Eldholm, V; Grandjean, L; Didelot, X; Balloux, F; van Dorp, L (2024) Detection of a historic reservoir of bedaquiline/clofazimine resistance-associated variants in Mycobacterium tuberculosis GENOME MEDICINE 16 34
Vieira, A et al. (2024) Rapid expansion and international spread of M1UK in the post-pandemic UK upsurge of Streptococcus pyogenes NATURE COMMUNICATIONS 15 3916
Oliver, MCA; Graham, M; Gass, KM; Medley, GF; Clark, J; Davis, EL; Reimer, LJ; King, JD; Pouwels, KB; Hollingsworth, TD (2024) Reducing the Antigen Prevalence Target Threshold for Stopping and Restarting Mass Drug Administration for Lymphatic Filariasis Elimination: A Model-Based Cost-effectiveness Simulation in Tanzania, India and Haiti CLINICAL INFECTIOUS DISEASES 78 S160-S168
Gordon, NS; Mcguigan, EK; Ondasova, M; Knight, J; Baxter, LA; Ott, S; Hastings, RK; Zeegers, MP; James, ND; Cheng, KK; Goel, A; Yu, MH; Arnold, R; Bryan, RT; Ward, DG (2024) Comparison and combination of mutation and methylation-based urine tests for bladder cancer detection BIOMARKER RESEARCH 12 133
Barquera, R et al. (2024) Ancient genomes reveal insights into ritual life at Chichén Itzá NATURE 630 568-569
Taylor, AJ et al. (2024) Epistasis, core-genome disharmony, and adaptation in recombining bacteria MBIO 15
van Daalen, KR et al. (2024) The 2024 Europe report of the Lancet Countdown on health and climate change: unprecedented warming demands unprecedented action LANCET PUBLIC HEALTH 9 e495-e522
Touloupou, P et al. (2024) An Ensemble Framework for Projecting the Impact of Lymphatic Filariasis Interventions Across Sub-Saharan Africa at a Fine Spatial Scale CLINICAL INFECTIOUS DISEASES 78 S108-S116
Dyer, NP; Päuker, B; Baxter, L; Gupta, A; Bunk, B; Overmann, J; Diricks, M; Dreyer, V; Niemann, S; Holt, KE; Rahman, M; Brown, PE; Stark, R; Zhou, ZM; Ott, S; Nübel, U (2024) EnteroBase in 2025: exploring the genomic epidemiology of bacterial pathogens NUCLEIC ACIDS RESEARCH
Prada, JM et al. (2024) Subnational Projections of Lymphatic Filariasis Elimination Targets in Ethiopia to Support National Level Policy CLINICAL INFECTIOUS DISEASES 78 S117-S125
Monod, M et al. (2024) Longitudinal population-level HIV epidemiologic and genomic surveillance highlights growing gender disparity of HIV transmission in Uganda NATURE MICROBIOLOGY 9
Cong, BB et al. (2024) Changes in the global hospitalisation burden of respiratory syncytial virus in young children during the COVID-19 pandemic: a systematic analysis LANCET INFECTIOUS DISEASES 24 361-374
2023
Guzmán-Rincón, LM; Hill, EM; Dyson, L; Tildesley, MJ; Keeling, MJ (2023) Bayesian estimation of real-time epidemic growth rates using Gaussian processes: local dynamics of SARS-CoV-2 in England JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS 72 1413-1434
Cavallaro, M; Dyson, L; Tildesley, MJ; Todkill, D; Keeling, MJ (2023) Spatio-temporal surveillance and early detection of SARS-CoV-2 variants of concern: a retrospective analysis JOURNAL OF THE ROYAL SOCIETY INTERFACE 20 20230410
Keeling, MJ; Moore, S; Penman, BS; Hill, EM (2023) The impacts of SARS-CoV-2 vaccine dose separation and targeting on the COVID-19 epidemic in England NATURE COMMUNICATIONS 14 740
Helekal, D; Keeling, M; Grad, YH; Didelot, X (2023) Estimating the fitness cost and benefit of antimicrobial resistance from pathogen genomic data JOURNAL OF THE ROYAL SOCIETY INTERFACE 20 20230074
McKendrick, JQ; Tennant, WSD; Tildesley, MJ (2023) Modelling seasonality of Lassa fever incidences and vector dynamics in Nigeria PLOS NEGLECTED TROPICAL DISEASES 17 e0011543
Gowers, RP; Richardson, MJE (2023) Upcrossing-rate dynamics for a minimal neuron model receiving spatially distributed synaptic drive PHYSICAL REVIEW RESEARCH 5 23095
Tomás, RMF; Dallman, R; Congdon, TR; Gibson, MI (2023) Cryopreservation of assay-ready hepatocyte monolayers by chemically-induced ice nucleation: preservation of hepatic function and hepatotoxicity screening capabilities BIOMATERIALS SCIENCE 11 7639-7654
Lagunas, B; Richards, L; Sergaki, C; Burgess, J; Pardal, AJ; Hussain, RMF; Richmond, BL; Baxter, L; Roy, P; Pakidi, A; Stovold, G; Vázquez, S; Ott, S; Schäfer, P; Gifford, ML (2023) Rhizobial nitrogen fixation efficiency shapes endosphere bacterial communities and Medicago truncatula host growth MICROBIOME 11 146
Hill, EM; Prosser, NS; Brown, PE; Ferguson, E; Green, MJ; Kaler, J; Keeling, MJ; Tildesley, MJ (2023) Incorporating heterogeneity in farmer disease control behaviour into a livestock disease transmission model PREVENTIVE VETERINARY MEDICINE 219 106019
Vasdekis, G; Roberts, GO (2023) SPEED UP ZIG-ZAG ANNALS OF APPLIED PROBABILITY 33 4693-4746
Lovell-Read, FA; Parnell, S; Cunniffe, NJ; Thompson, RN (2023) Using 'sentinel' plants to improve early detection of invasive plant pathogens PLOS COMPUTATIONAL BIOLOGY 19 e1010884
Huang, CI; Crump, RE; Crowley, EH; Hope, A; Bessell, PR; Shampa, C; Miaka, EM; Rock, KS (2023) A modelling assessment of short- and medium-term risks of programme interruptions for gambiense human African trypanosomiasis in the DRC PLOS NEGLECTED TROPICAL DISEASES 17 e0011299
Platt, A; Lutton, EJ; Offord, E; Bretschneider, T (2023) MiCellAnnGELo: annotate microscopy time series of complex cell surfaces with 3D virtual reality BIOINFORMATICS 39 btad013
Jeger, MJ; Fielder, H; Beale, T; Szyniszewska, AM; Parnell, S; Cunniffe, NJ (2023) What Can Be Learned by a Synoptic Review of Plant Disease Epidemics and Outbreaks Published in 2021? PHYTOPATHOLOGY 113 1141-1158
Didelot, X; Helekal, D; Kendall, M; Ribeca, P (2023) Distinguishing imported cases from locally acquired cases within a geographically limited genomic sample of an infectious disease BIOINFORMATICS 39
Vrljicak, P; Lucas, ES; Tryfonos, M; Muter, J; Ott, S; Brosens, JJ (2023) Dynamic chromatin remodeling in cycling human endometrium at single-cell level CELL REPORTS 42 113525
Brand, SPC; Cavallaro, M; Cumming, F; Turner, C; Florence, I; Blomquist, P; Hilton, J; Guzman-Rincon, LM; House, T; Nokes, DJ; Keeling, MJ (2023) The role of vaccination and public awareness in forecasts of Mpox incidence in the United Kingdom NATURE COMMUNICATIONS 14
Althobaity, Y; Tildesley, MJ (2023) Modelling the impact of non-pharmaceutical interventions on the spread of COVID-19 in Saudi Arabia SCIENTIFIC REPORTS 13 843
Offord, E; Lutton, JE; Bretschneider, T (2023) CELL MEMBRANE FEATURE DETECTION USING GRAPH NEURAL NETWORKS 2023 IEEE 20TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING, ISBI
Hill, EM (2023) Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England JOURNAL OF THEORETICAL BIOLOGY 557 111331
Marinho, JF Jr; Monteiro, JFCLS; de Carvalho, AWS; de Carvalho, FG; Cavalcanti, MD; Shaw, J; Courtenay, O; Brandao, SP (2023) High levels of infectiousness of asymptomatic Leishmania (Viannia) braziliensis infections in wild rodents highlights their importance in the epidemiology of American Tegumentary Leishmaniasis in Brazil PLOS NEGLECTED TROPICAL DISEASES 17 e0010996
Courtenay, O; Marinho, JF Jr; Brito, MEF; Monteiro, JFCLS; Shaw, JJ; Brandao, SP (2023) Incidence of Human and Free-Ranging Wild Rodent Infections with Leishmania (Viannia) braziliensis, Aetiological Agent of Cutaneous Leishmaniasis PATHOGENS 12 1395
Jenkins, PA; Pollock, M; Roberts, GO (2023) Flexible Bayesian Inference for Diffusion Processesusing Splines METHODOLOGY AND COMPUTING IN APPLIED PROBABILITY 25 83
Corbella, A; Presanis, AM; Birrell, PJ; De Angelis, D (2023) Alice Corbella, Anne M Presanis, Paul J Birrell and Daniela De Angelis's contribution to the Discussion of 'The Second Discussion Meeting on Statistical aspects of the Covid-19 Pandemic' JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY 186
Rysava, K; Tildesley, MJ (2023) Identification of dynamical changes of rabies transmission under quarantine: Community-based measures towards rabies elimination PLOS COMPUTATIONAL BIOLOGY 19 e1011187
Lutton, JE; Coker, HLE; Paschke, P; Munn, CJ; King, JS; Bretschneider, T; Kay, RR (2023) Formation and closure of macropinocytic cups in Dictyostelium CURRENT BIOLOGY 33 3083
Beck-Johnson, LM; Gorsich, EE; Hallman, C; Tildesley, MJ; Miller, RS; Webb, CT (2023) An exploration of within-herd dynamics of a transboundary livestock disease: A foot and mouth disease case EPIDEMICS 42 100668
Keeling, MJ (2023) Patterns of reported infection and reinfection of SARS-CoV-2 in England JOURNAL OF THEORETICAL BIOLOGY 556 111299
van den Bosch, F; McRoberts, N; Bourhis, Y; Parnell, S; Hassall, KL (2023) The value of volunteer surveillance for the early detection of biological invaders JOURNAL OF THEORETICAL BIOLOGY 560 111385
Reid, D et al. (2023) Feasibility and acceptability of longitudinal sample and data collection: learning from the sexually transmissible enteric infections in men who have sex with men (STEIM) pilot study SEXUALLY TRANSMITTED INFECTIONS 99 A99-A100
Didelot, X; Franceschi, V; Frost, SDW; Dennis, A; Volz, EM (2023) Model design for nonparametric phylodynamic inference and applications to pathogen surveillance VIRUS EVOLUTION 9 vead028
Mahony, CB; Copper, L; Vrljicak, P; Noyvert, B; Constantinidou, C; Browne, S; Pan, Y; Palles, C; Ott, S; Higgs, MR; Monteiro, R (2023) Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency CELL REPORTS 42 112571
Kaba, D et al. (2023) Towards the sustainable elimination of gambiense human African trypanosomiasis in Cote d'Ivoire using an integrated approach PLOS NEGLECTED TROPICAL DISEASES 17 e0011514
Antillon, M et al. (2023) Health economic evaluation of strategies to eliminate gambiense human African trypanosomiasis in the Mandoul disease focus of Chad PLOS NEGLECTED TROPICAL DISEASES 17 e0011396
Gomez, LRE; Savin, C; Andrianaivoarimanana, V; Rahajandraibe, S; Randriantseheno, LN; Zhou, ZM; Kocher, A; Didelot, X; Rajerison, M; Kühnert, D (2023) Phylogenetic analysis of the origin and spread of plague in Madagascar PLOS NEGLECTED TROPICAL DISEASES 17 e0010362
Gonçalves, FB; Latuszynski, KG; Roberts, GO (2023) Exact Bayesian Inference for Diffusion-Driven Cox Processes JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
Agrawal, S; Vats, D; Latuszynski, K; Roberts, GO (2023) OPTIMAL SCALING OF MCMC BEYOND METROPOLIS ADVANCES IN APPLIED PROBABILITY 55 492-509
Davis, EL; Crump, RE; Medley, GF; Solomon, AW; Pemmaraju, VRR; Hollingsworth, TD (2023) A modelling analysis of a new multi-stage pathway for classifying achievement of public health milestones for leprosy PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 378 20220408
Chase-Topping, M et al. (2023) Analysis of Escherichia coli O157 strains in cattle and humans between Scotland and England & Wales: implications for human health MICROBIAL GENOMICS 9 1090
Gallagher, KE et al. (2023) Symptom prevalence and secondary attack rate of SARS-CoV-2 in rural Kenyan households: A prospective cohort study INFLUENZA AND OTHER RESPIRATORY VIRUSES 17 e13185
Norman, CA; Krishnakumar, SS; Timofeeva, Y; Volynski, KE (2023) The release of inhibition model reproduces kinetics and plasticity of neurotransmitter release in central synapses COMMUNICATIONS BIOLOGY 6 1091
Roberts, GO; Rosenthal, JS (2024) Football group draw probabilities and corrections CANADIAN JOURNAL OF STATISTICS-REVUE CANADIENNE DE STATISTIQUE 52 659-677
Roberts, GO; Rosenthal, JS (2023) Polynomial Convergence Rates of Piecewise Deterministic Markov Processes METHODOLOGY AND COMPUTING IN APPLIED PROBABILITY 25 6
Kendall, M; Tsallis, D; Wymant, C; Di Francia, A; Balogun, Y; Didelot, X; Ferretti, L; Fraser, C (2023) Epidemiological impacts of the NHS COVID-19 app in England and Wales throughout its first year NATURE COMMUNICATIONS 14 858
Gonçalves, FB; Latuszynski, K; Roberts, GO (2023) Exact Monte Carlo likelihood-based inference for jump-diffusion processes JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY 85 732-756
Nyagwange, J et al. (2023) Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES 127 11-16
Mwanga, MJ et al. (2023) New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March-May 2023 EMERGING INFECTIOUS DISEASES 29 2376-2379
Owuor, DC; de Laurent, ZR; Nyawanda, BO; Emukule, GO; Kondor, R; Barnes, JR; Nokes, DJ; Agoti, CN; Chaves, SS (2023) Genetic and potential antigenic evolution of influenza A(H1N1)pdm09 viruses circulating in Kenya during 2009-2018 influenza seasons SCIENTIFIC REPORTS 13 22342
Lambisia, AW; Makori, TO; Mutunga, M; Cheruiyot, R; Murunga, N; Quick, J; Githinji, G; Nokes, DJ; Houldcroft, CJ; Agoti, CN (2023) Genomic epidemiology of human adenovirus F40 and F41 in coastal Kenya: A retrospective hospital-based surveillance study (2013-2022) VIRUS EVOLUTION 9 vead023
Rushmore, J; Beechler, BR; Tavalire, H; Gorsich, EE; Charleston, B; Devan-Song, A; Glidden, CK; Jolles, AE (2023) The heterogeneous herd: Drivers of close-contact variation in African buffalo and implications for pathogen invasion ECOLOGY AND EVOLUTION 13 e10447
Eames, KTD; Tang, ML; Hill, EM; Tildesley, MJ; Read, JM; Keeling, MJ; Gog, JR (2023) Coughs, colds and ?freshers? flu?survey in the University of Cambridge, 2007-2008 EPIDEMICS 42 100659
Chan, YLE; Irvine, MA; Prystajecky, N; Sbihi, H; Taylor, M; Joffres, Y; Schertzer, A; Rose, C; Dyson, L; Hill, EM; Tildesley, M; Tyson, JR; Hoang, LMN; Galanis, E (2023) Emergence of SARS-CoV-2 Delta Variant and Effect of Nonpharmaceutical Interventions, British Columbia, Canada EMERGING INFECTIOUS DISEASES 29 1999-2007
Dingle, KE; Freeman, J; Didelot, X; Quan, TP; Eyre, DW; Swann, J; Spittal, WD; Clark, EV; Jolley, KA; Walker, AS; Wilcox, MH; Crook, DW (2023) Penicillin Binding Protein Substitutions Cooccur with Fluoroquinolone Resistance in Epidemic Lineages of Multidrug-Resistant Clostridioides difficile MBIO 14
Yenew, B et al. (2023) A smooth tubercle bacillus from Ethiopia phylogenetically close to the Mycobacterium tuberculosis complex NATURE COMMUNICATIONS 14 7519
Shaw, JJ; Marinho, JF Jr; Courtenay, O; Brandao, SP (2023) Assessing reservoir host status in leishmaniasis with special reference to the infectiousness of Leishmania (Viannia) braziliensis infections in wild rodents REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL 56 e05032023
Dai, HS; Pollock, M; Roberts, GO (2023) Bayesian fusion: scalable unification of distributed statistical analyses JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY 85 84-107
Ward, DG; Baxter, L; Ott, S; Gordon, NS; Wang, JH; Patel, P; Piechocki, K; Silcock, L; Sale, C; Zeegers, MP; Cheng, K; James, ND; Bryan, RT (2023) Highly Sensitive and Specific Detection of Bladder Cancer via Targeted Ultra-deep Sequencing of Urinary DNA EUROPEAN UROLOGY ONCOLOGY 6 67-75
Mughal, SR; Niazi, SA; Do, T; Gilbert, SC; Didelot, X; Radford, DR; Beighton, D (2023) Genomic Diversity among Actinomyces naeslundii Strains and Closely Related Species MICROORGANISMS 11 254
Baxter, L et al. (2023) Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection SCIENTIFIC REPORTS 13 1060
Ortiz, AT; Kendall, M; Storey, N; Hatcher, J; Dunn, H; Roy, S; Williams, R; Williams, C; Goldstein, RA; Didelot, X; Harris, K; Breuer, J; Grandjean, L (2023) Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaks ELIFE 12 e84384
Jibreel, T et al. (2023) Host preference and human blood index of Phlebotomus orientalis, an exophilic sand fly vector of visceral leishmaniasis in eastern Sudan MEDICAL AND VETERINARY ENTOMOLOGY 37 782-792
Guarido, MM; Fourie, I; Meno, K; Mendes, A; Riddin, MA; MacIntyre, C; Manyana, S; Johnson, T; Schrama, M; Gorsich, EE; Brooke, BD; Almeida, APG; Venter, M (2023) Alphaviruses Detected in Mosquitoes in the North-Eastern Regions of South Africa, 2014 to 2018 VIRUSES-BASEL 15 414
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Lewis, JM; Savage, RS; Beeching, NJ; Beadsworth, MBJ; Feasey, N; Covington, JA (2017) Identifying volatile metabolite signatures for the diagnosis of bacterial respiratory tract infection using electronic nose technology: A pilot study PLOS ONE 12 e0188879
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Smith, ME; Singh, BK; Irvine, MA; Stolk, WA; Subramanian, S; Hollingsworth, TD; Michael, E (2017) Predicting lymphatic filariasis transmission and elimination dynamics using a multi-model ensemble framework EPIDEMICS 18 16-28
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Everitt, RG; Johansen, AM; Rowing, E; Evdemon-Hogan, M (2017) Bayesian model comparison with un-normalised likelihoods STATISTICS AND COMPUTING 27 403-422
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Torrecilha, RBP; Utsunomiya, YT; Bosco, AM; Almeida, BF; Pereira, PP; Narciso, LG; Pereira, DCM; Baptistiolli, L; Calvo-Bado, L; Courtenay, O; Nunes, CM; Ciarlini, PC (2016) Correlations between peripheral parasite load and common clinical and laboratory alterations in dogs with visceral leishmaniasis PREVENTIVE VETERINARY MEDICINE 132 83-87
Smith, CA; McAinsh, AD; Burroughs, NJ (2016) Human kinetochores are swivel joints that mediate microtubule attachments ELIFE 5 e16159
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Emukule, GO; Mott, JA; Spreeuwenberg, P; Viboud, C; Commanday, A; Muthoka, P; Munywoki, PK; Nokes, DJ; van Der Velden, K; Paget, JW (2016) Influenza activity in Kenya, 2007-2013: timing, association with climatic factors, and implications for vaccination campaigns INFLUENZA AND OTHER RESPIRATORY VIRUSES 10 375-385
Ford, KJ; Lang, S; Pollard, AJ; McCarthy, ND (2016) A quantitative review of healthcare professionals' questions to a local immunization advice service: 4299 enquiries from 3 years JOURNAL OF PUBLIC HEALTH 38 578-584
Barchinger, SE; Pirbadian, S; Sambles, C; Baker, CS; Leung, KM; Burroughs, NJ; El-Naggar, MY; Golbeck, JH (2016) Regulation of Gene Expression in Shewanella oneidensis MR-1 during Electron Acceptor Limitation and Bacterial Nanowire Formation APPLIED AND ENVIRONMENTAL MICROBIOLOGY 82 5428-5443
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Adamson, A; Boddington, C; Downton, P; Rowe, W; Bagnall, J; Lam, C; Maya-Mendoza, A; Schmidt, L; Harper, CV; Spiller, DG; Rand, DA; Jackson, DA; White, MRH; Paszek, P (2016) Signal transduction controls heterogeneous NF-kappa B dynamics and target gene expression through cytokine-specific refractory states NATURE COMMUNICATIONS 7 12057
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Owor, BE; Masankwa, GN; Mwango, LC; Njeru, RW; Agoti, CN; Nokes, DJ (2016) Human metapneumovirus epidemiological and evolutionary patterns in Coastal Kenya, 2007-11 BMC INFECTIOUS DISEASES 16 301
Armond, JW; Vladimirou, E; McAinsh, AD; Burroughs, NJ (2016) KiT: a MATLAB package for kinetochore tracking BIOINFORMATICS 32 1917-1919
Kiti, MC; Tizzoni, M; Kinyanjui, TM; Koech, DC; Munywoki, PK; Meriac, M; Cappa, L; Panisson, A; Barrat, A; Cattuto, C; Nokes, DJ (2016) Quantifying social contacts in a household setting of rural Kenya using wearable proximity sensors EPJ DATA SCIENCE 5 21
Metras, R; Cavalerie, L; Dommergues, L; Merot, P; Edmunds, WJ; Keeling, MJ; Cetre-Sossah, C; Cardinale, E (2016) The Epidemiology of Rift Valley Fever in Mayotte: Insights and Perspectives from 11 Years of Data PLOS NEGLECTED TROPICAL DISEASES 10 e0004783
Chalker, VJ; Smith, A; Al-Shahib, A; Botchway, S; Macdonald, E; Daniel, R; Phillips, S; Platt, S; Doumith, M; Tewolde, R; Coelho, J; Jolley, KA; Underwood, A; McCarthy, ND (2016) Integration of Genomic and Other Epidemiologic Data to Investigate and Control a Cross-Institutional Outbreak of Streptococcus pyogenes EMERGING INFECTIOUS DISEASES 22 973-980
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Piper, J; Assi, SA; Cauchy, P; Ladroue, C; Cockerill, PN; Bonifer, C; Ott, S (2015) Wellington-bootstrap: differential DNase-seq footprinting identifies cell-type determining transcription factors BMC GENOMICS 16 1000
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Brown, P; Baxter, L; Hickman, R; Beynon, J; Moore, JD; Ott, S (2013) MEME-LaB: motif analysis in clusters BIOINFORMATICS 29 1696-1697
Hickman, R; Hill, C; Penfold, CA; Breeze, E; Bowden, L; Moore, JD; Zhang, PJ; Jackson, A; Cooke, E; Bewicke-Copley, F; Mead, A; Beynon, J; Wild, DL; Denby, KJ; Ott, S; Buchanan-Wollaston, V (2013) A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves PLANT JOURNAL 75 26-39
Woodcock, DJ; Vance, KW; Komorowski, M; Koentges, G; Finkenstadt, B; Rand, DA (2013) A hierarchical model of transcriptional dynamics allows robust estimation of transcription rates in populations of single cells with variable gene copy number BIOINFORMATICS 29 1519-1525
Webb, SD; Keeling, MJ; Boots, M (2013) The role of spatial population structure on the evolution of parasites with acquired immunity and demography JOURNAL OF THEORETICAL BIOLOGY 324 21-31
Jenkins, DJ; Finkenstadt, B; Rand, DA (2013) A temporal switch model for estimating transcriptional activity in gene expression BIOINFORMATICS 29 1158-1165
Laranjeiro, R; Tamai, TK; Peyric, E; Krusche, P; Ott, S; Whitmore, D (2013) Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110 6835-6840
Anderson, LJ; Dormitzer, PR; Nokes, DJ; Rappuoli, R; Roca, A; Graham, BS (2013) Strategic priorities for respiratory syncytial virus (RSV) vaccine development VACCINE 31 B209-B215
Loebel, A; Le Be, JV; Richardson, MJE; Markram, H; Herz, AVM (2013) Matched Pre- and Post-Synaptic Changes Underlie Synaptic Plasticity over Long Time Scales JOURNAL OF NEUROSCIENCE 33 6257-6266
Black, AJ; House, T; Keeling, MJ; Ross, JV (2013) Epidemiological consequences of household-based antiviral prophylaxis for pandemic influenza JOURNAL OF THE ROYAL SOCIETY INTERFACE 10 20121019
Darkins, R; Cooke, EJ; Ghahramani, Z; Kirk, PDW; Wild, DL; Savage, RS (2013) Accelerating Bayesian Hierarchical Clustering of Time Series Data with a Randomised Algorithm PLOS ONE 8 e59795
Bond, M; Croft, W; Tyson, R; Bretschneider, T; Davey, J; Ladds, G (2013) Quantitative analysis of human ras localization and function in the fission yeast Schizosaccharomyces pombe YEAST 30 145-156
Gould, PD; Ugarte, N; Domijan, M; Costa, M; Foreman, J; MacGregor, D; Rose, K; Griffiths, J; Millar, AJ; Finkenstadt, B; Penfield, S; Rand, DA; Halliday, KJ; Hall, AJW (2013) Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures MOLECULAR SYSTEMS BIOLOGY 9 650
Webb, SD; Keeling, MJ; Boots, M (2013) A theoretical study of the role of spatial population structure in the evolution of parasite virulence THEORETICAL POPULATION BIOLOGY 84 36-45
Fuller, JA et al. (2013) Estimation of the National Disease Burden of Influenza-Associated Severe Acute Respiratory Illness in Kenya and Guatemala: A Novel Methodology PLOS ONE 8 e56882
Sande, CJ; Mutunga, MN; Medley, GF; Cane, PA; Nokes, DJ (2013) Group- and Genotype-Specific Neutralizing Antibody Responses Against Respiratory Syncytial Virus in Infants and Young Children With Severe Pneumonia JOURNAL OF INFECTIOUS DISEASES 207 489-492
Munywoki, PK; Ohuma, EO; Ngama, M; Bauni, E; Scott, JAG; Nokes, DJ (2013) Severe Lower Respiratory Tract Infection in Early Infancy and Pneumonia Hospitalizations among Children, Kenya EMERGING INFECTIOUS DISEASES 19 223-229
Quinnell, RJ; Carson, C; Reithinger, R; Garcez, LM; Courtenay, O (2013) Evaluation of rK39 Rapid Diagnostic Tests for Canine Visceral Leishmaniasis: Longitudinal Study and Meta-Analysis PLOS NEGLECTED TROPICAL DISEASES 7 e1992
Sutherland, WJ et al. (2013) Identification of 100 fundamental ecological questions JOURNAL OF ECOLOGY 101 58-67
2012
Okiro, EA; Ngama, M; Bett, A; Nokes, DJ (2012) The Incidence and Clinical Burden of Respiratory Syncytial Virus Disease Identified through Hospital Outpatient Presentations in Kenyan Children PLOS ONE 7 e52520
Onyango, CO; Njeru, R; Kazungu, S; Achilla, R; Bulimo, W; Welch, SR; Cane, PA; Gunson, RN; Hammitt, LL; Scott, JAG; Berkley, JA; Nokes, DJ (2012) Influenza Surveillance Among Children With Pneumonia Admitted to a District Hospital in Coastal Kenya, 2007-2010 JOURNAL OF INFECTIOUS DISEASES 206 S61-S67
Kirk, P; Griffin, JE; Savage, RS; Ghahramani, Z; Wild, DL (2012) Bayesian correlated clustering to integrate multiple datasets BIOINFORMATICS 28 3290-3297
Agoti, CN; Mwihuri, AG; Sande, CJ; Onyango, CO; Medley, GF; Cane, PA; Nokes, DJ (2012) Genetic Relatedness of Infecting and Reinfecting Respiratory Syncytial Virus Strains Identified in a Birth Cohort From Rural Kenya JOURNAL OF INFECTIOUS DISEASES 206 1532-1541
Danon, L; House, TA; Read, JM; Keeling, MJ (2012) Social encounter networks: collective properties and disease transmission JOURNAL OF THE ROYAL SOCIETY INTERFACE 9 2826-2833
Tildesley, MJ; Ryan, SJ (2012) Disease Prevention versus Data Privacy: Using Landcover Maps to Inform Spatial Epidemic Models PLOS COMPUTATIONAL BIOLOGY 8 e1002723
Ohuma, EO; Okiro, EA; Ochola, R; Sande, CJ; Cane, PA; Medley, GF; Bottomley, C; Nokes, DJ (2012) The Natural History of Respiratory Syncytial Virus in a Birth Cohort: The Influence of Age and Previous Infection on Reinfection and Disease AMERICAN JOURNAL OF EPIDEMIOLOGY 176 794-802
van Hoek, AJ; Ngama, M; Ismail, A; Chuma, J; Cheburet, S; Mutonga, D; Kamau, T; Nokes, DJ (2012) A Cost Effectiveness and Capacity Analysis for the Introduction of Universal Rotavirus Vaccination in Kenya: Comparison between Rotarix and RotaTeq Vaccines PLOS ONE 7 e47511
House, T; Inglis, N; Ross, JV; Wilson, F; Suleman, S; Edeghere, O; Smith, G; Olowokure, B; Keeling, MJ (2012) Estimation of outbreak severity and transmissibility: Influenza A(H1N1)pdm09 in households BMC MEDICINE 10 117
Baxter, L; Jironkin, A; Hickman, R; Moore, J; Barrington, C; Krusche, P; Dyer, NP; Buchanan-Wollaston, V; Tiskin, A; Beynon, J; Denby, K; Ott, S (2012) Conserved Noncoding Sequences Highlight Shared Components of Regulatory Networks in Dicotyledonous Plants PLANT CELL 24 3949-3965
Webb, C; Ngama, M; Ngatia, A; Shebbe, M; Morpeth, S; Mwarumba, S; Bett, A; Nokes, DJ; Seale, AC; Kazungu, S; Munywoki, P; Hammitt, LL; Scott, JAG; Berkley, JA (2012) Treatment Failure Among Kenyan Children With Severe Pneumonia-A Cohort Study PEDIATRIC INFECTIOUS DISEASE JOURNAL 31 E152-E157
Spencer, SEF; Marshall, J; Pirie, R; Campbell, D; Baker, MG; French, NP (2012) The spatial and temporal determinants of campylobacteriosis notifications in New Zealand, 2001-2007 EPIDEMIOLOGY AND INFECTION 140 1663-1677
Xue, M; Momiji, H; Rabbani, N; Barker, G; Rand, DA; Thornalley, PJ (2012) Control of ARE-linked gene expression by cytoplasm-nucleus translocational oscillations of Nrf2 FREE RADICAL BIOLOGY AND MEDICINE 53 S37-S37
Xue, M; Momiji, H; Barker, G; Rand, DA; Rabbani, N; Thornalley, PJ (2012) Multi-tiered protective response of Nrf2 transactivational activity in endothelial cells in vitro FREE RADICAL BIOLOGY AND MEDICINE 53 S233-S233
Xue, M; Shaheen, F; Momiji, H; Barker, G; Rand, DA; Rabbani, N (2012) Effect of nrf2 activators on protein oxidative damage in human endothelial cells in vitro FREE RADICAL BIOLOGY AND MEDICINE 53 S100-S101
Windram, O et al. (2012) Arabidopsis Defense against Botrytis cinerea: Chronology and Regulation Deciphered by High-Resolution Temporal Transcriptomic Analysis PLANT CELL 24 3530-3557
Martin, JF; Santos-Beneit, F; Rodriguez-Garcia, A; Sola-Landa, A; Smith, MCM; Ellingsen, TE; Nieselt, K; Burroughs, NJ; Wellington, EMH (2012) Transcriptomic studies of phosphate control of primary and secondary metabolism in Streptomyces coelicolor APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 95 61-75
Iqbal, M; Mast, Y; Amin, R; Hodgson, DA; Wohlleben, W; Burroughs, NJ (2012) Extracting regulator activity profiles by integration of de novo motifs and expression data: characterizing key regulators of nutrient depletion responses in Streptomyces coelicolor NUCLEIC ACIDS RESEARCH 40 5227-5239
Rock, KS; Keeling, MJ; Wood, DA (2012) Modelling the future of the Hawaiian honeycreeper: An ecological and epidemiological problem ECOLOGICAL MODELLING 235 26-35
Vernon, MC; Keeling, MJ (2012) Impact of regulatory perturbations to disease spread through cattle movements in Great Britain PREVENTIVE VETERINARY MEDICINE 105 110-117
Keeling, MJ; Shattock, A (2012) Optimal but unequitable prophylactic distribution of vaccine EPIDEMICS 4 78-85
Onyango, CO; Welch, SR; Munywoki, PK; Agoti, CN; Bett, A; Ngama, M; Myers, R; Cane, PA; Nokes, DJ (2012) Molecular epidemiology of human rhinovirus infections in Kilifi, coastal Kenya JOURNAL OF MEDICAL VIROLOGY 84 823-831
Tildesley, MJ; Smith, G; Keeling, MJ (2012) Modeling the spread and control of foot-and-mouth disease in Pennsylvania following its discovery and options for control PREVENTIVE VETERINARY MEDICINE 104 224-239
Hammitt, LL; Kazungu, S; Morpeth, SC; Gibson, DG; Mvera, B; Brent, AJ; Mwarumba, S; Onyango, CO; Bett, A; Akech, DO; Murdoch, DR; Nokes, DJ; Scott, JAG (2012) A Preliminary Study of Pneumonia Etiology Among Hospitalized Children in Kenya CLINICAL INFECTIOUS DISEASES 54 S190-S199
Thomas, L; Hodgson, DA; Wentzel, A; Nieselt, K; Ellingsen, TE; Moore, J; Morrissey, ER; Legaie, R; Wohlleben, W; Rodriguez-Garcia, A; Martin, JF; Burroughs, NJ; Wellington, EMH; Smith, MCM (2012) Metabolic Switches and Adaptations Deduced from the Proteomes of Streptomyces coelicolor Wild Type and phoP Mutant Grown in Batch Culture MOLECULAR & CELLULAR PROTEOMICS 11 M111.013797
Du, CJ; Ferguson, JG; Hawkins, PT; Stephens, LR; Bretschneider, T (2012) Local Shape Representation in 3D: from Weighted Spherical Harmonics to Spherical Wavelets PROCEEDINGS OF THE BRITISH MACHINE VISION CONFERENCE 2012
2011
Downey, MJ; Jeziorska, DM; Ott, S; Tamai, TK; Koentges, G; Vance, KW; Bretschneider, T (2011) Extracting Fluorescent Reporter Time Courses of Cell Lineages from High-Throughput Microscopy at Low Temporal Resolution PLOS ONE 6 e27886
Tsibidis, GD; Burroughs, NJ; Gaze, W; Wellington, EMH (2011) Semi-automated Acanthamoeba polyphaga detection and computation of Salmonella typhimurium concentration in spatio-temporal images MICRON 42 911-920
Tildesley, MJ; Volkova, VV; Woolhouse, MEJ (2011) Potential for epidemic take-off from the primary outbreak farm via livestock movements BMC VETERINARY RESEARCH 7 76
Travis, ER et al. (2011) An Inter-Laboratory Validation of a Real Time PCR Assay to Measure Host Excretion of Bacterial Pathogens, Particularly of Mycobacterium bovis PLOS ONE 6 e27369
Cooke, EJ; Savage, RS; Kirk, PDW; Darkins, R; Wild, DL (2011) Bayesian hierarchical clustering for microarray time series data with replicates and outlier measurements BMC BIOINFORMATICS 12 399
Mwambi, H; Ramroop, S; White, LJ; Okiro, EA; Nokes, DJ; Shkedy, Z; Molenberghs, G (2011) A frequentist approach to estimating the force of infection for a respiratory disease using repeated measurement data from a birth cohort STATISTICAL METHODS IN MEDICAL RESEARCH 20 551-570
Morrissey, ER; Juarez, MA; Denby, KJ; Burroughs, NJ (2011) Inferring the time-invariant topology of a nonlinear sparse gene regulatory network using fully Bayesian spline autoregression BIOSTATISTICS 12 682-694
Yuan, YY; Savage, RS; Markowetz, F (2011) Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes PLOS COMPUTATIONAL BIOLOGY 7 e1002227
House, T; Baguelin, M; Van Hoek, AJ; White, PJ; Sadique, Z; Eames, K; Read, JM; Hens, N; Melegaro, A; Edmunds, WJ; Keeling, MJ (2011) Modelling the impact of local reactive school closures on critical care provision during an influenza pandemic PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 278 2753-2760
Munywoki, PK; Hamid, F; Mutunga, M; Welch, S; Cane, P; Nokes, DJ (2011) Improved Detection of Respiratory Viruses in Pediatric Outpatients with Acute Respiratory Illness by Real-Time PCR Using Nasopharyngeal Flocked Swabs JOURNAL OF CLINICAL MICROBIOLOGY 49 3365-3367
Burroughs, NJ; Kohler, K; Miloserdov, V; Dustin, ML; van der Merwe, PA; Davis, DM (2011) Boltzmann Energy-based Image Analysis Demonstrates that Extracellular Domain Size Differences Explain Protein Segregation at Immune Synapses PLOS COMPUTATIONAL BIOLOGY 7 e1002076
Alijani, AK; Richardson, MJE (2011) Rate response of neurons subject to fast or frozen noise: From stochastic and homogeneous to deterministic and heterogeneous populations PHYSICAL REVIEW E 84 11919
Hammitt, LL; Kazungu, S; Welch, S; Bett, A; Onyango, CO; Gunson, RN; Scott, JAG; Nokes, DJ (2011) Added Value of an Oropharyngeal Swab in Detection of Viruses in Children Hospitalized with Lower Respiratory Tract Infection JOURNAL OF CLINICAL MICROBIOLOGY 49 2318-2320
Nyiro, JU; Sanders, EJ; Ngetsa, C; Wale, S; Awuondo, K; Bukusi, E; Price, MA; Amornkul, PN; Nokes, DJ (2011) Seroprevalence, predictors and estimated incidence of maternal and neonatal Herpes Simplex Virus Type 2 infection in semi-urban women in Kilifi, Kenya BMC INFECTIOUS DISEASES 11 155
Komorowski, M; Costa, MJ; Rand, DA; Stumpf, MPH (2011) Sensitivity, robustness, and identifiability in stochastic chemical kinetics models PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108 8645-8650
Bryan, SJ; Burroughs, NJ; Evered, C; Sacharz, J; Nenninger, A; Mullineaux, CW; Spence, EM (2011) Loss of the SPHF Homologue Slr1768 Leads to a Catastrophic Failure in the Maintenance of Thylakoid Membranes in Synechocystis sp PCC 6803 PLOS ONE 6 e19625
Keeling, MJ; White, PJ (2011) Targeting vaccination against novel infections: risk, age and spatial structure for pandemic influenza in Great Britain JOURNAL OF THE ROYAL SOCIETY INTERFACE 8 661-670
Burroughs, NJ; Ferreira, M; Oliveira, BMPM; Pinto, AA (2011) Autoimmunity arising from bystander proliferation of T cells in an immune response model MATHEMATICAL AND COMPUTER MODELLING 53 1389-1393
Burroughs, NJ; Oliveira, BMPM; Pinto, AA; Ferreira, M (2011) Immune response dynamics MATHEMATICAL AND COMPUTER MODELLING 53 1410-1419
Harper, CV; Finkenstadt, B; Woodcock, DJ; Friedrichsen, S; Semprini, S; Ashall, L; Spiller, DG; Mullins, JJ; Rand, DA; Davis, JRE; White, MRH (2011) Dynamic Analysis of Stochastic Transcription Cycles PLOS BIOLOGY 9 e1000607
Pontiroli, A; Travis, ER; Sweeney, FP; Porter, D; Gaze, WH; Mason, S; Hibberd, V; Holden, J; Courtenay, O; Wellington, EMH (2011) Pathogen Quantitation in Complex Matrices: A Multi-Operator Comparison of DNA Extraction Methods with a Novel Assessment of PCR Inhibition PLOS ONE 6 e17916
House, T; Keeling, MJ (2011) Epidemic prediction and control in clustered populations JOURNAL OF THEORETICAL BIOLOGY 272 1-7
Spencer, SEF; O'Neill, PD (2011) THE PROBABILITY OF CONTAINMENT FOR MULTITYPE BRANCHING PROCESS MODELS FOR EMERGING EPIDEMICS JOURNAL OF APPLIED PROBABILITY 48 173-188
Breeze, E et al. (2011) High-Resolution Temporal Profiling of Transcripts during Arabidopsis Leaf Senescence Reveals a Distinct Chronology of Processes and Regulation PLANT CELL 23 873-894
Levi, F; Mosekilde, E; Rand, DA (2011) Advancing systems medicine and therapeutics through biosimulation INTRODUCTION INTERFACE FOCUS 1 3-6
Domijan, M; Rand, DA (2011) Balance equations can buffer noisy and sustained environmental perturbations of circadian clocks INTERFACE FOCUS 1 177-186
Klyuch, BP; Richardson, MJE; Dale, N; Wall, MJ (2011) The dynamics of single spike-evoked adenosine release in the cerebellum JOURNAL OF PHYSIOLOGY-LONDON 589 283-295
House, T; Keeling, MJ (2011) Insights from unifying modern approximations to infections on networks JOURNAL OF THE ROYAL SOCIETY INTERFACE 8 67-73
Rand, DA (2011) Network Control Analysis for Time-Dependent Dynamical States DYNAMICS, GAMES AND SCIENCE II 2 1-24
Didelot, X; Everitt, RG; Johansen, AM; Lawson, DJ (2011) Likelihood-free estimation of model evidence BAYESIAN ANALYSIS 6 49-76
Almeida, JP; Fisher, AM; Pinto, AA; Rand, DA (2011) Anosov and Circle Diffeomorphisms DYNAMICS, GAMES AND SCIENCE I 1 11-23
Burroughs, NJ; Ferreira, M; Martins, J; Oliveira, BMPM; Pinto, AA; Stollenwerk, N (2011) Dynamics and Biological Thresholds DYNAMICS, GAMES AND SCIENCE I 1 183-191
Pinto, AA; Rand, DA (2011) Uniformly hyperbolic diffeomorphisms in every surfaces JOURNAL OF DIFFERENCE EQUATIONS AND APPLICATIONS 17 1031-1047
Burroughs, NJ; Ferreira, M; Oliveira, BMPM; Pinto, AA (2011) A transcritical bifurcation in an immune response model JOURNAL OF DIFFERENCE EQUATIONS AND APPLICATIONS 17 1101-1106
2010
Pinto, AA; Burroughs, NJ; Ferreira, M; Oliveira, BMPM (2010) Dynamics of Immunological Models ACTA BIOTHEORETICA 58 391-404
Du, CJ; Marcello, M; Spiller, DG; White, MRH; Bretschneider, T (2010) Interactive Segmentation of Clustered Cells via Geodesic Commute Distance and Constrained Density Weighted Nystrom Method CYTOMETRY PART A 77A 1137-1147
Kohler, K; Xiong, SQ; Brzostek, J; Mehrabi, M; Eissmann, P; Harrison, A; Cordoba, SP; Oddos, S; Miloserdov, V; Gould, K; Burroughs, NJ; van der Merwe, PA; Davis, DM (2010) Matched Sizes of Activating and Inhibitory Receptor/Ligand Pairs Are Required for Optimal Signal Integration by Human Natural Killer Cells PLOS ONE 5 e15374
Edwards, KD; Akman, OE; Knox, K; Lumsden, PJ; Thomson, AW; Brown, PE; Pokhilko, A; Kozma-Bognar, L; Nagy, F; Rand, DA; Millar, AJ (2010) Quantitative analysis of regulatory flexibility under changing environmental conditions MOLECULAR SYSTEMS BIOLOGY 6 424
Richardson, MJE; Swarbrick, R (2010) Firing-Rate Response of a Neuron Receiving Excitatory and Inhibitory Synaptic Shot Noise PHYSICAL REVIEW LETTERS 105 178102
Koohy, H; Dyer, NP; Reid, JE; Koentges, G; Ott, S (2010) An alignment-free model for comparison of regulatory sequences BIOINFORMATICS 26 2391-2397
Agoti, CN; Mbisa, JL; Bett, A; Medley, GF; Nokes, DJ; Cane, PA (2010) Intrapatient Variation of the Respiratory Syncytial Virus Attachment Protein Gene JOURNAL OF VIROLOGY 84 10425-10428
Picot, E; Krusche, P; Tiskin, A; Carre, I; Ott, S (2010) Evolutionary analysis of regulatory sequences (EARS) in plants PLANT JOURNAL 64 165-176
Nair, H; Gessner, BD; Nokes, DJ; Theodoratou, E; Rudan, I; Madhi, SA; Simoes, EAF; Campbell, H (2010) Childhood mortality due to respiratory syncytial virus Reply LANCET 376 872-873
Morrissey, ER; Juarez, MA; Denby, KJ; Burroughs, NJ (2010) On reverse engineering of gene interaction networks using time course data with repeated measurements BIOINFORMATICS 26 2305-2312
Carson, C; Quinnell, RJ; Holden, J; Garcez, LM; Deborggraeve, S; Courtenay, O (2010) Comparison of Leishmania OligoC-TesT PCR with Conventional and Real-Time PCR for Diagnosis of Canine Leishmania Infection JOURNAL OF CLINICAL MICROBIOLOGY 48 3325-3330
Nokes, DJ; Peenze, I; Netshifhefhe, L; Abwao, J; De Beer, MC; Seheri, M; Williams, TN; Page, N; Steele, D (2010) Rotavirus Genetic Diversity, Disease Association, and Temporal Change in Hospitalized Rural Kenyan Children JOURNAL OF INFECTIOUS DISEASES 202 S180-S186
Turner, DA; Paszek, P; Woodcock, DJ; Nelson, DE; Horton, CA; Wang, YJ; Spiller, DG; Rand, DA; White, MRH; Harper, CV (2010) Physiological levels of TNF alpha stimulation induce stochastic dynamics of NF-kappa B responses in single living cells JOURNAL OF CELL SCIENCE 123 2834-2843
Vance, KW; Shaw, HM; Rodriguez, M; Ott, S; Goding, CR (2010) The Retinoblastoma Protein Modulates Tbx2 Functional Specificity MOLECULAR BIOLOGY OF THE CELL 21 2770-2779
Rorres, C; Pelletier, STK; Keeling, MJ; Smith, G (2010) Estimating the kernel parameters of premises-based stochastic models of farmed animal infectious disease epidemics using limited, incomplete, or ongoing data THEORETICAL POPULATION BIOLOGY 78 46-53
Morelli, G; Didelot, X; Kusecek, B; Schwarz, S; Bahlawane, C; Falush, D; Suerbaum, S; Achtman, M (2010) Microevolution of Helicobacter pylori during Prolonged Infection of Single Hosts and within Families PLOS GENETICS 6 e1001036
Didelot, X; Maiden, MCJ (2010) Impact of recombination on bacterial evolution TRENDS IN MICROBIOLOGY 18 315-322
Akman, OE; Rand, DA; Brown, PE; Millar, AJ (2010) Robustness from flexibility in the fungal circadian clock BMC SYSTEMS BIOLOGY 4 88
Paszek, P; Ryan, S; Ashall, L; Sillitoe, K; Harper, CV; Spiller, DG; Rand, DA; White, MRH (2010) Population robustness arising from cellular heterogeneity PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 11644-11649
Savage, RS; Ghahramani, Z; Griffin, JE; de la Cruz, BJ; Wild, DL (2010) Discovering transcriptional modules by Bayesian data integration BIOINFORMATICS 26 i158-i167
Spiller, DG; Wood, CD; Rand, DA; White, MRH (2010) Measurement of single-cell dynamics NATURE 465 736-745
Yang, J; Kohler, K; Davis, DM; Burroughs, NJ (2010) An improved strip FRAP method for estimating diffusion coefficients: correcting for the degree of photobleaching JOURNAL OF MICROSCOPY 238 240-253
Berkley, JA; Munywoki, P; Ngama, M; Kazungu, S; Abwao, J; Bett, A; Lassauniere, R; Kresfelder, T; Cane, PA; Venter, M; Scott, JAG; Nokes, DJ (2010) Viral Etiology of Severe Pneumonia Among Kenyan Infants and Children JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 303 2051-2057
Keeling, MJ; Danon, L; Vernon, MC; House, TA (2010) Individual identity and movement networks for disease metapopulations PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 8866-8870
Nair, H et al. (2010) Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis LANCET 375 1545-1555
Sanchez-Romero, MA; Busby, SJW; Dyer, NP; Ott, S; Millard, AD; Grainger, DC (2010) Dynamic Distribution of SeqA Protein across the Chromosome of Escherichia coli K-12 MBIO 1 e00012-10
Ross, JV; House, T; Keeling, MJ (2010) Calculation of Disease Dynamics in a Population of Households PLOS ONE 5 e9666
House, T; Keeling, MJ (2010) The Impact of Contact Tracing in Clustered Populations PLOS COMPUTATIONAL BIOLOGY 6 e1000721
Carson, C; Quinnell, RJ; Day, MJ; Courtenay, O (2010) Comparison of monoclonal and polyclonal antibodies for the detection of canine IgG1 and IgG2, and associations with infection outcome in Leishmania infantum naturally infected dogs VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 133 264-268
House, T; Hall, I; Danon, L; Keeling, MJ (2010) Contingency planning for a deliberate release of smallpox in Great Britain-the role of geographical scale and contact structure BMC INFECTIOUS DISEASES 10 25
Bern, C; Courtenay, O; Alvar, J (2010) Of Cattle, Sand Flies and Men: A Systematic Review of Risk Factor Analyses for South Asian Visceral Leishmaniasis and Implications for Elimination PLOS NEGLECTED TROPICAL DISEASES 4 e599
Okiro, EA; White, LJ; Ngama, M; Cane, PA; Medley, GF; Nokes, DJ (2010) Duration of shedding of respiratory syncytial virus in a community study of Kenyan children BMC INFECTIOUS DISEASES 10 15
Tildesley, MJ; House, TA; Bruhn, MC; Curry, RJ; O'Neil, M; Allpress, JLE; Smith, G; Keeling, MJ (2010) Impact of spatial clustering on disease transmission and optimal control PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 1041-1046
Reid, JE; Evans, KJ; Dyer, N; Wernisch, L; Ott, S (2010) Variable structure motifs for transcription factor binding sites BMC GENOMICS 11 30
Nieselt, K et al. (2010) The dynamic architecture of the metabolic switch in Streptomyces coelicolor BMC GENOMICS 11 10
Pinto, AA; Rand, DA; Ferreira, F (2010) Arc exchange systems and renormalization JOURNAL OF DIFFERENCE EQUATIONS AND APPLICATIONS 16 347-371
Pinto, AA; Rand, DA (2010) Train tracks with C1+ self-renormalizable structures JOURNAL OF DIFFERENCE EQUATIONS AND APPLICATIONS 16 945-962
Tyson, RA; Epstein, DBA; Anderson, KI; Bretschneider, T (2010) High Resolution Tracking of Cell Membrane Dynamics in Moving Cells: an Electrifying Approach MATHEMATICAL MODELLING OF NATURAL PHENOMENA 5 34-55