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Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases

Fage CD, Passmore M, Tatman BP, Smith HG, Jian X, Dissanayake UC, Foran ME, Cisneros GA, Challis GL, Lewandowski JR, Jenner M. Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in <i>trans</i>-Acyltransferase Polyketide Synthases. JACS Au. 2024 Nov 18;5(1):144-157. doi: 10.1021/jacsau.4c00837. PMID: 39886563; PMCID: PMC11775670.

Tue 27 May 2025, 10:26