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Maternity & Obstetrics

The Maternity Research theme at Warwick CTU, in collaboration with University Hospitals Coventry and Warwick (UHCW), focuses on the development, implementation and evaluation of interventions to improve maternal and infant health and well-being before, during and after pregnancy. Working across both Warwick Clinical Trials Unit and UHCW our multi-disciplinary team including service users, develop and lead multi-centre randomised controlled trials, and a portfolio of primary and secondary research studies using quantitative and qualitative approaches and evidence synthesis, to generate high quality evidence to meet priority health needs before, during and after pregnancy.

The focus of our research covers issues relevant to the maternal and infant life-course, from understanding how to prevent recurrent early pregnancy miscarriage and pre-term labour, evaluation of interventions during labour to improve maternal and infant outcomes, optimal management of medically complex pregnancies, and how postnatal contacts could be planned and managed to address maternal physical and psychological co-morbidity, including better understanding of breastfeeding support needs.

Our current work is funded by the NIHR HTA programme, NIHR EME programme, NIHR Research for Patient Benefit programme, NIHR Public Health Research programme, Tommy’s Charity, Burdett Trust for Nursing, Department of Health, and NIHR CLAHRC South London.

We have a range of expertise and experience in supervision of post-graduate and post-doctoral students. If you are interested in post-graduate study, including applications for fellowship awards in a relevant area, please contact Professor Bick debra dot bick at warwick dot ac dot uk.

Recent publications:

Quenby S, Gallos ID, Dhillon-Smith RK, Podesek M, Stephenson MD, Fisher JD, Brosens JJ, Brewin J, Ramhorst R, Lucas ES, McCoy RC, Anderson R, Daher S, Regan L, Al-Memar M, Bourne T, MacIntyre DA, Rai R, Christiansen OB, Sugiura-Ogasawara M, Odendaal J, Devall AJ, Bennett PR, Petrou S, Coomarasamy A. Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss. Lancet. 2021 Apr 23:S0140-6736(21)00682-6. doi: 10.1016/S0140-6736(21)00682-6. Epub ahead of print. PMID: 33915094.

Coomarasamy A, Gallos ID, Papadopoulou A, Dhillon-Smith RK, Al-Memar M, Brewin J, Christiansen OB, Stephenson MD, Oladapo OT, Wijeyaratne CN, Small R, Bennett PR, Regan L, Goddijn M, Devall AJ, Bourne T, Brosens JJ, Quenby S. Sporadic miscarriage: evidence to provide effective care. Lancet. 2021 Apr 23:S0140-6736(21)00683-8. doi: 10.1016/S0140-6736(21)00683-8. Epub ahead of print. PMID: 33915095.

Coomarasamy A, Dhillon-Smith RK, Papadopoulou A, Al-Memar M, Brewin J, Abrahams VM, Maheshwari A, Christiansen OB, Stephenson MD, Goddijn M, Oladapo OT, Wijeyaratne CN, Bick D, Shehata H, Small R, Bennett PR, Regan L, Rai R, Bourne T, Kaur R, Pickering O, Brosens JJ, Devall AJ, Gallos ID, Quenby S. Recurrent miscarriage: evidence to accelerate action. Lancet. 2021 Apr 23:S0140-6736(21)00681-4. doi: 10.1016/S0140-6736(21)00681-4. Epub ahead of print. PMID: 33915096

Zanganeh, Mandana, Jordan, Mary, Mistry, Hema, 2021. A systematic review of economic evaluations for donor human milk versus standard feeding in infants. Maternal and Child Nutrition

Hunter C, Bick D. (2019) Early-career midwives' experiences of perineal assessment and repair after normal vaginal birth. Br J of Midwifery.

Isaacs R, van Teijlingen E, Wee M, Hundley V, Smith G, Bick D, Gale-Andrews L. (2019). Design errors in vital sign charts used in consultant-led maternity units in the United Kingdom. Int J of Obstetric Anaesthesia.

Domoney J, Fulton E, Stanley N, McIntyre A, Heslin M, Byford S, Bick D, Ramchandani P, MacMillan H, Howard LM, Trevillion K (2019). For Baby’s Sake: Intervention Development and Evaluation Design of a Whole-Family Perinatal Intervention to Break the Cycle of Domestic Abuse. Journal of Family Violence.

Baldwin S, Bick D. (2019) Evidence from a systematic review on first-time fathers’ mental health and well-being needs. Journal of Health Visiting.

Lockwood Estrin G, Ryan EG, Trevillion K, Demilew J, Bick D, Pickles A, Howard L. (2019). Mental disorders in young pregnant women: findings from an early pregnancy cohort. Br J of Psychiatry Open.

Davie P, Bick D, Chilcott J. To What Extent Does Maternal Body Mass Index (BMI) Predict Intentions, Attitudes or Practices of Early Infant Feeding? Maternal and Child Nutrition. 2019 May 6:e12837. doi: 10.1111/mcn.12837. [Epub ahead of print]

Bick D, Ashworth A, Meyer F, Taylor C. High-risk Pregnancy due to Mental and Physical Co-morbidity. Chapter 5. The FIGO Continuous Textbook of Women’s Medicine – Obstetrics Module. Vol 7. DOI 10.3843/GLOWM.00000.

Fernandez Turienzo C, Bick D, Bollard M, Brigante L, Briley A, Coxon K, Cross P, Healey A, Mehta M, Melaugh A, Moulla J, Seed PT, Shennan AH, Singh C, Tribe RM and Sandall J. POPPIE: protocol for a randomised controlled pilot trial of continuity of midwifery care for women at increased risk of preterm birth. Trials. In press.

Da Silva Tanganhito D, Chang YS, Bick D. Breastfeeding experiences and perspectives among women with postnatal depression: A qualitative evidence synthesis. Women and Birth. In press.

Research project pages:
Recently completed trials:

The SWAN Study - Click here for details


Members of the Maternity and Obstetrics theme have published a three-paper report published in The Lancet highlights that the current approach to miscarriage care must be improved – see recent publications.

Key People:

Professor Debra Bick - theme lead

Professor Siobhan Quenby

Dr Joanne Fisher

Dr Hema Mistry

Dr Sharin Baldwin

Dr Nithya Sukumar