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Trials in follow up

patient talking to a medical professional

These trials are closed to recruitment but observations on the effects of the intervention and data collection are ongoing.

Trials in follow up

Trial name About the trial Trial type Chief Investigator
AIR Main UK study of ankle fracture rehabilitation – multicentre randomised
controlled trial

Surgery, Trauma & Orthopaedics

Prof Rebecca Kearney

ALIFE2 Anticoagulants for LIving FoEtuses in women with recurrent miscarriage and inherited thrombophilia Reproductive health Prof Siobhan Quenby
ARTemis Determining whether the addition to neo-adjuvant chemotherapy of an anti-angiogenic agent bevacizumab is more effective than standard chemotherapy alone in terms of short-term and long-term outcome in women presenting with HER2-negative early breast cancer. Cancer Prof Helena Earl
COMPRESS-RCT A feasibility randomised controlled trial of mechanical chest compression devices for in-hospital cardiac arrest Emergency and critical care Dr Keith Couper
COMPRESS-SIM A feasibility study of the use of a mechanical chest compression device for inhospital
cardiac arrest
Emergency and critical care Dr Keith Couper
De-ESCALATE Determining the optimum treatment for patients with HPV+ OPSCC. Cancer Professor Hisham Mehanna
DRAFFT A randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius Trauma and orthopaedics

Prof Matthew Costa

FixDT Comparing intramedullary nail fixation with locking plate fixation for patients with a distal tibia fracture. Trauma and orthopaedics Prof Matthew Costa
KOPS Investigating why total Knee Arthroplasty (TKA) is a treatment that has a proven benefit; however a proportion of people, possibly as high as one in six, have less satisfactory outcomes after surgery. Trauma and orthopaedics Prof Damian Griffin
MAMMO-50 Mammographic surveillance in breast cancer patients aged 50 years or older. Cancer Prof Janet Dunn
Metro

Meniscal tear outcome study (METRO). The purpose of this study is find out what is the current management of young patients (patients under 55) with meniscal tears in the population and what happens to these patients.

Surgery, Trauma & Orthopaedics

Associate Clinical Prof Andrew Metcalfe

Persephone Comparing six months Herceptin® treatment with twelve months, in patients with early stage breast cancer. Cancer Prof Helena Earl
PIPS A Feasibility Study into Patellla Instability: Physiotherapy or Surgery Surgery, Trauma & Orthopaedics Associate Clinical Prof Andrew Metcalfe
REGARD

A Feasibility Randomised Controlled Trial to compare REgional versus General Anaesthesia in Reducing Delirium in patients with Hip Fractures

Emergency and Critical Care

Dr Joyce Yeung

START:REACTS Sub-acromial spacer for Tears Affecting Rotator cuff Tendons: a Randomised, Efficient, Adaptive Clinical Trial in Surgery (START:REACTS) Surgery, Trauma & Orthopaedics

Associate Clinic Prof Andrew Metcalfe

TEAMM Assessing the benefit of antibiotic prophylaxis and its effect on healthcare associated infection Cancer

Prof Mark Drayson