iRehab
Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge: a randomised controlled assessor-blind clinical and cost-effectiveness trial with internal pilot
People treated in intensive care need a great deal of special care and support. After discharge from hospital, some people find their muscles are still weak and their ability to exercise and to do everyday things may still be affected. They can also have confused memories of their time in the intensive care unit. For most people, these problems get better on their own, but for other people, they may continue for a long time after leaving hospital. iRehab will investigate the effects of:
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- A six week multicomponent, rehabilitation intervention, delivered remotely by a core intervention team. In brief, the intervention includes four components: weekly symptom management; targeted exercise; psychological support and information/peer support.
- Compared to Standard Care, not involving structured rehabilitation.
Sample Size: 428 participants (control n=197; intervention n=231)
Primary outcome is health related quality of life at 8 weeks post randomisation. Secondary outcomes include health-related QoL (at six months), physical function, fatigue, anxiety and depression, healthcare resource use at eight weeks and six months post-randomisation
Trial Duration: 1st January 2022- 31st December 2024 (36 months)
337 Participants
50 Recruiting Sites
As of 16th September 2024
Latest News:
2024
4th July: We're waiting to hear the outcome of the extension application with the NIHR
- PLEASE CONTINUE TO RECRUIT IN THE MEANTIME -
30th April: 250 participants have been randomised to iRehab
5th March: Half way target of 214 reached
14th Febuary: 200 participants have been randomised to iRehab
8th January: 190 participants have been randomised to iRehab
2023
18th August: 110 participants have been randomised to iRehab
9th August: 35 sites open to recruitment
8th August: 100 participants have been randomised to iRehab
7th July: 90 participants have been randomised to iRehab
19th June: 80 participants have been randomised to iRehab
11th May: 60 participants randomised to iRehab
26th April: 50 participants randomised to iRehab
12th April: Non-Substantial Amendment 07 implementation date
3rd March: 25 sites open to recruitment
28th Feb: iRehab is now registered with API Scheme
30th Jan: 10 participants randomised to iRehab
13th December: First participant randomised to iRehab
18th November: First 5 sites have received the green light to commence recruitment
18th November: iRehab is now open to recruitment
Chief Investigator:
Dr Brenda O'Neill
Co-Chief Investigator:
Prof Danny McAuley
Sponsor:
Funder:
Registration Number:
Enquiries:
Please direct all enquiries to the iRehab team;
Kerry Raynes: Trial Manager
Sarah Lowe, Trial Manager
Katherine Jones, Research Fellow
Email: iRehab@warwick.ac.uk
Tel: 02476151367