Funder: NIHR HTA Programme  Total grant £405,281.60.

Start date: October 2013 End date: January 2016.

PI: Martin Underwood (Warwick Medical School)

Collaborators: Kirstie Haywood (Warwick): Total 11 co-applicants.

Description: Feasibility Study: 1) Systematic reviews of evidence-based addressing five key questions relevant to the proposed RCT (including PRO related questions; 2) Consensus conference; 3) Feasibility RCT. Kirstie Haywood will be responsible for all PRO-related aspects of the feasibility study including a review of evidence (between-group difference), methodological work exploring how best to interpret between group difference in scores and evaluation of PRO application in the RCT (including evaluation of individualised measurement (Patient Generated Index)). KH will also advise on the consensus conference and contribute as an expert in measurement science.

Progress: Monthly team meetings since October 2013. Significant work undertaken to complete systematic review and conduct secondary analysis of available data to support score interpretation (between group differences). Contribute to development of the Consensus Conference – held 26^th June 2014. Contribute towards data analysis from this event. Working towards one group publication following the consensus conference and an additional methodological paper re BGD. Focus towards main feasibility RCT from July 2014 onwards.

Publications: Paper from consensus meeting in print. Protocol paper and ‘Between group differences’ paper under review.