Background

I studied Physics (5 year degree) at the Universidad Autonoma de Madrid, specialising in theoretical physics. After my degree I worked for a year in industry (programmer and SAP consultant). I have also worked on Nuclear Physics (Spanish National Research Council), Theoretical Neuroscience (Theoretical Physics Department UAM) and Bioinformatics (Spanish National Cancer Research Centre).

PhD

I am working on Bayesian gene regulatory network inference in Streptomyces coelicolor. The project is part of STREAM, a European project involving research groups from UK, Germany, Holland, Spain and Norway.

Visiting Scholar

From April to October I was a visiting scholar at the Collins Lab.

PhD Supervisors

My PhD supervisors are Professor Nigel Burroughs (main supervisor) and Professor David Hodgson

PhD Advisory Committee

Professor Jim Beynon (Wariwick HRI), Julia Brettschneider (Statistics) and Hendrik Schaefer (Biological Sciences)

Code

An R/Bioconductor package (GRENITS, Gene Regulatory Newtork Inference using Time Series) implementing the methods published below can be found here.

Publications

Morrissey, E.R., Juárez, M.A., Denby, K.J. and Burroughs, N.J. 2011. Inferring the time-invariant topology of a nonlinear sparse gene regulatory network using fully Bayesian spline autoregression Biostatistics 2011; doi:10.1093/biostatistics/kxr009

Morrissey, E.R., Juárez, M.A., Denby, K.J. and Burroughs, N.J. 2010. On reverse engineering of gene interaction networks using time course data with repeated measurements. Bioinformatics 2010; doi: 10.1093/bioinformatics/btq421

STREAM Consortium, 2010. The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics 2010, 11:10

Pre PhD

Morrissey E, Diaz-Uriarte R. 2009. Pomelo II: finding differentially expressed genes. Nucl. Acids. Res, doi: 10.1093/nar/gkp366.

Diaz-Uriarte, R., Alibés, A., Morrissey, E. R., Cañada, A., Rueda, O.M., Neves, M. L. 2007. Asterias: integrated analysis of expression and aCGH data using an open-source, web-based, parallelized software suite. Nucleic Acids Research,2007, 35, No. suppl_2 W75-W80.

Alibés, A., Morrissey, E. R., Cañada, A., Rueda, O. M., Casado, D., Yankilevich, P., and Díaz-Uriarte, R. 2006. Asterias: a parallelized web-based suite for the analysis of expression and aCGH data. Cancer Informatics, 2 :1-9.

Turrión M., Tengblad O., Borge M., Reillo E. , Morrissey E.R., and Santana M. On line Release Simulator of Radioactive Beams produced by ISOL technique AIP Conf. Proc. -- February 12, 2007 -- Volume 884, pp. 278-284

Teaching

I taught the problems classes for Modelling and Statistics in Systems Biology (BS917) 2008/2009

Conferences Attended

11 th International Conference on Systems Biology (Edinburgh, UK), Oct 2010: Network Perturbations: Simultaneous inference of networks and external perturbations (POSTER)

Networks: Dynamics and Flows NET2009 (Warwick, UK), 2009: Inferring gene regulatory network topology using a non linear sparse Dynamic Bayesian Network model (TALK)

SysMO Evaluation Conference (Vienna, Austria), May 2009: Regulatory Networks: Inference and Experimental Validation (POSTER)

Sparsity in Machine Learning and Statistics - Cumberland Lodge (London, UK), April 2009 : Inferring genetic regulation using Sparse Bayesian Regression with Penalised Splines (POSTER)

Postgraduate Student Symposium HRI (Warwick, UK), 2009: From gene expression to regulatory networks (POSTER)

9^th International Conference on Systems Biology (Gothenburg, Sweden), August 2008: Bayesian inference of gene networks using a flexible sparse Dynamic Bayesian Network model (POSTER)

Annual Computational Neuroscience Meeting (Wisconsin, USA), 2005: Populations of Hodgkin-Huxley type neurons under slow background noise (POSTER)