Hello, my name is Azzedine Dabo, On this page I’m going to tell you about myself and what I am currently researching at Warwick University. Thank you for visiting my page and please feel free to contact me if required.
I achieved a 2.1 in my BSc in Biological Chemistry at Aston Universityin Birmingham. I have also obtained a MSc in Analytical Science: Measurementand Instrumental Techniques (AS: MIT). During this course a number of importanttechniques were taught in depth e.g. Electrochemistry, Mass Spectrometry,Chromatography, Imaging and Nuclear Magnetic Resonance (NMR). NMR was, for me,the most enjoyable module of the year. As a result, I ended up taking a PhD collaborative project with Pfizer in the solid state NMR Warwick group.
Research: Current Project
Solid state NMR based approaches for facilitating chromatography method development.
High pressure liquid chromatography (HPLC) is a wonderful technique that allows us to separate mixtures of compounds by providing both qualitative (elution time) and quantitative (peak integration) information. One main limitation of HPLC ismethod development. This involves the selection of optimum parameters to provide the best separation results for a given sample e.g. temperature, pressure, pH, column dimensions, column material and mobile phase composition.
Solid state NMR (ssNMR) is a fascinating technique that has variety of uses e.g. determines structure, molecular motions and interactions of molecules, from small drugs to proteins and nucleic acids.
The main difference between liquid and solid state NMR is that in liquid, the anisotropic interactions,i.e. interactions that depend on their orientation with respect to the direction of the external magnetic field, are averaged while in ssNMR they are not. As a result broad peaks are observed instead of nice resolved sharp peaks. Magic Angle Spinning (MAS) is a technique that can suppress these anisotropic interactions improving significantly the resolution of the recorded NMR spectra.
In my project I investigate samples composed of mixtures of solutions and solids. 1H MAS NMR experiments are performed using our impressive 500 MHz Bruker Spectrometer using a 4mm MAS Bruker Rotor and Probe.
The main aim of this project is to understand the interaction between the analyte and its mobile phase and analyte with a stationary phase. In order to do that we measure various relaxation rates on a series of different analytes with one mobile phase and 3 different stationary phases.
My Life Outside University
I love spending time going to the gym, going out with my friends, going on holidays and enjoy cooking. Like any other student, love playing video games.
Magnetic Resonance Centre
Millburn Hill Road
University of Warwick Science Park