Dr Matthew Naish

Supervisor Details

Contact Details

Dr Matthew Naish

School of Life Sciences, University of Warwick

Scientific Background

Research Interests

In my lab, we explore how the genome’s architecture is regulated and inherited, focusing broadly on chromatin, the protein DNA complex that packages DNA. We are particularly interested in centromeres (specialised chromosome regions essential for accurate chromosome segregation) and use them as a model locus to investigate how unique chromatin domains are established, maintained, and regulated. By studying how centromeric chromatin is specified and preserved, we aim to uncover how these structures promote genome stability and ensure the faithful inheritance of genetic information. To address these questions, we use a combination of cutting-edge functional genomics, long-read DNA sequencing, live cell imaging and epigenomic approaches. Leveraging the powerful genetic tools and fully sequenced genomes of the model plant Arabidopsis thaliana we can dissect the molecular factors that define centromere identity and function.

Supervision Style

In three words or phrases: Curiosity-driven, collaborative and outcome-oriented

Provision of Training

This will initially led by myself at the bench. Specific equipment training provided by Research Technology Platforms (RPTs). As you progress I also encourage students to be proactive in seeking training and development opportunities with others in the department and University as a whole.

Progression Monitoring and Management

Lab members are expected to take ownership of their projects and act as the main driving force behind them. As we are a small lab, we discuss your projects regularly — through informal weekly conversations and a more formal lab meeting, where members present on a rotational basis. You should keep me updated on new results, challenges, and plans. Based on your progress, I will provide advice and guidance to help steer your project toward the best outcomes. I will also outline my expectations for your development on a monthly basis.

Communication

I am always available to be contacted by email, additionally we use ‘Slack’ for communicating within the group and use this as a platform to share files, documents and updates.

Meetings

PhD Students can expect scheduled meetings with me at least once per week. These meetings will be face-to-face. I am usually contactable for an instant response on every working day.

Work Patterns

The timing of work in my lab is completely flexible, and (other than attending pre-arranged meetings) I expect students to manage their own time.

Notice Period for Feedback

I need at least 2 weeks' notice to provide feedback on written work of up to 5,000 words.

MIBTP Project Details

Primary supervisor for:

Project Title

See the PhD Opportunities section to see if this project is currently open for applications via MIBTP.

Please Note: The main page lists projects via BBSRC Research Theme(s) quoted and then relevant Topic(s).

Project Title

Secondary Supervisor(s):

University of Registration:

BBSRC Research Themes:

Sustainable Agriculture and Food (Animal Health and Welfare, Microbial Food Safety, Plant and Crop Science)
Renewable Resources and Clean Growth (Bio-energy, Industrial Biotechnology)
Understanding the Rules of Life (Immunology, Microbiology, Neuroscience and Behaviour, Plant Science, Soil Science, Stem Cells, Structural Biology, Systems Biology)
Integrated Understanding of Health (Ageing, Diet and Health, Pharmaceuticals, Regenerative Biology)

Project Outline

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Co-supervisor on a project / projects with supervisor name + link.