MEMVIE (Mathematical & Economic Modelling for Vaccination and Immunisation Evaluation)
From the end of 2013 until I left Warwick in March 2017, I was working on a 5-year project between Warwick and the UK Department of Health, entitled MEMVIE (Mathematical & Economic Modelling for Vaccination and Immunisation Evaluation). The project involves the construction of novel mathematical and statistical models for simulating the spread of infectious diseases in humans, and evaluating the cost-effectiveness of different vaccination interventions. I focused on several infections, including HPV (Human Papillomavirus), pertussis (whooping cough), Meningitis B and pneumoncoccal disease. The outputs of our models will be used in conjunction with independent modelling done by Public Health England (part of the Department of Health), to advise on future vaccination policy in the UK. The project is headed by Professor Matt Keeling, and my research partners include: Professor Graham Medley (London School of Hygiene and Tropical Medicine), Professor Martin Underwood, Professor Stavros Petrou, Dr. Sophie Staniszewska and Dr. Tinevimbo Shiri (Warwick Medical School).
Changes in invasive pneumococcal disease due to PCV7 serotypes following introduction of PCV7 to national immunisation programmes. Left plot: > 65 years old; right plot: all age groups.
Image taken from Shiri et al., "Indirect Impact of Childhood Pneumococcal Conjugate Vaccination on Invasive Pneumococcal Disease: A Global Systematic Review and Meta-analysis", The Lancet Global Health (2016).
- Matthew J. Keeling, Katherine A. Broadfoot and Samik Datta (2017), 'The impact of current infection levels on the cost-benefit of vaccination', Epidemics 21, 56-62. [ARTICLE]
- Tinevimbo Shiri, Samik Datta, Jason Madan, Alexander Tsertsvadze, Pamela Royle, Matthew J. Keeling, Noel McCarthy and Stavros Petrou (2017), 'Indirect Impact of Childhood Pneumococcal Conjugate Vaccination on Invasive Pneumococcal Disease: A Global Systematic Review and Meta-analysis', The Lancet Global Health 5(1), 51-59. [ARTICLE].
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