Gibson Group: Muhammad Hasan
Muhammad was born in Rawalpindi, Pakistan in 1984. He completed his schooling in many different countries, specifically, he did GCE 'O' Levels in Singapore (1998-2000) and GCE 'A' Levels in Pakistan (2001-2003). He was subsequently awarded the Reach Oxford Scholarship to read Mathematics at Magdalen College, Oxford (2004-2007).
In his final year he began to take a keen interest in Mathematical Biology and hence decided to enrol in the MSc + PhD programme in Mathematical Biology and Biophysical Chemistry at the Molecular Organisation and Assembly in Cells (MOAC) DTC. He then joined the Gibson group and set up the new lab at the Warwick Medical School.
Investigating the structure-activity relationship of ice-binding proteins to:
i) understand how these proteins function in their native environments.
ii) develop non-natural analogues and conjugates.
iii) explore their use as cryoprotective agents in laboratory and industrial contexts.
 Fayter, AER., Hasan, M., Congdon,TR., Kontopoulou, I., Gibson, M.I., European Polymer Journal, Ice Recrystallisation Inhibiting Polymers Prevent Irreversible Protein Aggregation During Solvent-Free Cryopreservation as Additives and as Covalent Polymer-Protein Conjugates, 2020, DOI: 10.1016/j.eurpolymj.2020.110036
 Baker, A.N., Richards, S.J., Guy, C.S., Congdon, T.R., Hasan, M., Zwetsloot, A.J., Gallo, A., Lewandowski, J.R, Stansfeld, P.J., Anne Straube, A., Walker, M., Chessa, S., Pergolizzi, G., Dedola, S., Field, R.A. and Gibson, M.I., ACS Central Science, The SARS-COV-2 spike protein binds sialic acids, and enables rapid detection in a lateral flow point of care diagnostic device, 2020., DOI: 10.1021/acscentsci.0c00855
 Tomas, MFR., Bailey, T.L., Hasan, M., Gibson, MI., Biomacromolecules, Extracellular Antifreeze Protein Significantly Enhance the Cryopreservation of Cell Monolayers, 2019, DOI:10.1021/acs.biomac.9b00951
 Ishibe, T., Congdon, TR., Stubbs C., Hasan, M., Sosso, G., Gibson, MI., ACS Macro Letters, Enhancement of Macromolecular Ice Recrystallisation Inhibition Activity by Exploiting Depletion Forces, 2019. DOI:10.1021/acsmacrolett.9b00386
 Biggs CI., Stubbs.C., Graham, B., Fayter, AER., Hasan, M., Gibson, MI. Macromolecular Bioscience. Mimicking the Ice Recystallization Activity of Biological Macromolecules. When is a New Polymer 'Active'?, 2019. DOI:10.1002/mabi.201900082
 Wilkins, LE., Hasan, M., Fayter, AER., Biggs, CI., Huband, S., Walker, M., Gibson, MI., Polymer Chemistry. Site-Specific Conjugation of Antifreeze Proteins onto Polymer-Stabilized Nanoparticles, 2019. DOI:10.1039/C8PY01719K
 Mitchell, DE., Deller, RC., Fayter, AC., Hasan, M., Gutierrez-Marcos, J., Gibson, MI., Materials Horizons. Ice-Recrystallization Inhibiting Polymers Protect Proteins Against Freeze-Stress and Enable Glycerol-Free Cryostorage, 2018. DOI:10.1039/C8MH00727F
 Hasan, M., Fayter, AC., Gibson, M.I., Biomacromolecules. Ice Recrystallization Inhibiting Polymers Enable Glycerol-Free Cryopreservation of Micro-organisms, 2018. DOI:10.1021/acs.biomac.8b00660
 Blackman, LD., Varlas, S., Arno, M.C., Houston, Z., Fletcher, N., Thurecht, K, Hasan, M., Gibson M.I., and O’Reilly, R.K. Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 2018. DOI:10.1021/acscentsci.8b00168
 Ieong, N. S., M. Hasan, D.J. Philips, Y. Saaka, R.K. O’Reilly, and M.I. Gibson. Polymers
with molecular weight dependent LCSTs are essential for cooperative behaviour.
Polymer Chemistry, 2012, 3, 794–799. DOI:10.1039/C2PY00604A
 Jenei, Z.A., G.Z.L. Warren, M. Hasan, V.A. Zammit and A.M. Dixon. Packing of transmembrane
domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and
malonyl-CoA sensitivity of the mitochondrial outer membrane protein. The FASEB
Journal, 2011, 25, 4522–4530. DOI:10.1096/FJ.11-192005
Reach Oxford Scholarship, Magdalen College, University of Oxford, 2004-2007.
Carl Blakey Scholarship, MOAC DTC, University of Warwick, 2010.
Biochemical Society Travel Grant to attend Biophysical Society Annual Meeting, 2019.
UKRI Innovation Fellowships: BBSRC Flexible Talent Mobility Account Award, 2018.
The Astbury Conversation, Leeds (UK), 2018
Cryobiology, Madrid (Spain), 2018
Biophysical Society Meeting, Baltimore (USA), 2019
Mathematics, Magdalen College, University of Oxford, 2004-2007
Mathematical Biology and Biophysical Chemistry, University of Warwick, 2010-2011
Mathematical Biology and Biophysical Chemistry, University of Warwick, 2011-2015
ORCID ID: orcid.org/0000-0003-3201-7184