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Gibson Group: Muhammad Hasan

Biography

Muhammad was born in Rawalpindi, Pakistan in 1984. He completed his schooling in many different countries, specifically, he did GCE 'O' Levels in Singapore (1998-2000) and GCE 'A' Levels in Pakistan (2001-2003). He was subsequently awarded the Reach Oxford Scholarship to read Mathematics at Magdalen College, Oxford (2004-2007).

In his final year he began to take a keen interest in Mathematical Biology and hence decided to enrol in the MSc + PhD programme in Mathematical Biology and Biophysical Chemistry at the Molecular Organisation and Assembly in Cells (MOAC) DTC. He then joined the Gibson group and set up the new lab at the Warwick Medical School.

Research Interests

Investigating the structure-activity relationship of ice-binding proteins to:

i) understand how these proteins function in their native environments.

ii) develop non-natural analogues and conjugates.

iii) explore their use as cryoprotective agents in laboratory and industrial contexts.

Publications

[3] Blackman, LD., Varlas, S., Arno, M.C., Houston, Z., Fletcher, N., Thurecht, K, Hasan, M., Gibson M.I., and O’Reilly, R.K. Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 2018, doi:10.1021/acscentsci.8b00168

[2] Ieong, N. S., M. Hasan, D.J. Philips, Y. Saaka, R.K. O’Reilly, and M.I. Gibson. Polymers
with molecular weight dependent LCSTs are essential for cooperative behaviour.
Polymer Chemistry, 2012, 3, 794–799. doi:10.1039/C2PY00604A

[1] Jenei, Z.A., G.Z.L. Warren, M. Hasan, V.A. Zammit and A.M. Dixon. Packing of transmembrane
domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and
malonyl-CoA sensitivity of the mitochondrial outer membrane protein. The FASEB
Journal, 2011, 25, 4522–4530. doi:10.1096/FJ.11-192005

Awards

Reach Oxford Scholarship, Magdalen College, University of Oxford (2004-2007)

Carl Blakey Scholarship, MOAC DTC, University of Warwick (2010)

Grants

UKRI Innovation Fellowships: BBSRC Flexible Talent Mobility Account Award, 2018

Photo

Education

BA (Hons.)

Mathematics, Magdalen College, University of Oxford, 2004-2007

MSc

Mathematical Biology and Biophysical Chemistry, University of Warwick, 2010-2011

PhD

Mathematical Biology and Biophysical Chemistry, University of Warwick, 2011-2015

Email: M.Hasan.1[at]warwick.ac.uk

ORCID ID: orcid.org/0000-0003-3201-7184