Gibson Group News
Review on Glycan-Based Diagnostics Published in ChemSoc Rev!
We have a long standing interest in how we can use biomaterials to probe, understand and exploit glycans (sugars) for a range of applications. During infection glycans are often the first thing a pathogen encounters and binds to. Hence there is an opportunity to use this binding event as a tool to sense or diagnose the presence of pathogens. In this review, written with Prof Rob Field (Manchester) and Simone Dedola (Iceni Glycoscience) we review the state of the art for using glycans in diagnostics and in particular how they can be used in lateral flow devices. Lateral flow devices have been widely used during COVID-19 pandemic, but typically rely on antibodies on gold nanoparticles (which give the red colour). We show how glycans have potential to be used alongside these.
Read the review here