Professor Gibson Awarded €2 Million ERC Grant
Matt has been awarded a 5 years, €2 Million European Research Council (ERC) grant to start in 2020 called 'ICE PACK'. The aim of this is to develop materials for storing biologics in the cold chain, with the aim of making advanced therapies more available through better transport. This will follow from his previous ERC grants (Starting and Proof of concept) which studied polymers which could prevent ice growth. News story is here.
Group Awarded ERC Funding for Clinical Translation of Cryopreservation
Professor Gibson has been awarded an ERC Proof of Concept Grant entitled 'Solvent Free Cryopreservation of Hematopeotic Stem Cells'. This grant is only available to ERC grant holders, to follow up on results obtained during the ERC grant to translate it to real world applications. This project will seek to revolutionise how we store bone marrow cells (hematopoetic stem cells) by using polymeric mimics of antifreeze proteins.
A Postdoctoral vacancy will be available soon on this project.
MRC Innovation Grant Awarded
In collaboration with Dr. Elizabeth Fullam (Life Sciences), we have been awarded a grant from the Medical Research Council (MRC) from the Cross Council AMR Theme 1 Initiative (1 of only 8 awards made). This will seek to develop new tools for targetting the cell wall of Tuberculosis to validate new antibacterial and diagnostic agents. There is a 2 year postdoctoral position associated with this grant, so please contact us if interested.
Research Grant funded from Leverhulme Trust
We have been awarded a research grant, joint with the group of Nick Waterfield (Warwick Medical School), from the Leverhulme Trust. The project involves using a combination of chemistry and molecular biology (a.k.a. synthetic biology) to understand the function and potential uses of naturally occuring molecular syringes. There will be a PDRA (Med School) and PhD (Chemistry) working on this project
Industrial Biocatalysis project funded
We are part of a large consortium of UK Universities and companies which has been awarded > £3.5 Million over 5 years to develop new methods to obtain speciality glycans (carbohydrates) using a combination of chemistry and enzymes, and translate these to applications. The GibsonGroup is actively involved in this project (details below) and a PDRA will be based at Warwick during this time.
This is funded by Innovate UK, along with BBSRC and EPSRC.
Chemo-enzymatic Synthesis of Speciality Glycans
The vision of the project centres around the translation of traditional and novel methodologies to develop sustainable and versatile platforms for the industrial production of glycans on scale. We will demonstrate the technology by targeting a set of novel glycan materials that are anticipated to have significant transformational potential in human health and disease in diagnostics and glycoengineering applications. This project requires an integrated approach featuring: 1) synthetic chemistry (unnatural building blocks) 2) biocatalysis (enzymatic synthesis of larger glycans) 3) showcasing glycan potential in diagnostics (glycoarray based platforms). The significant anticipated progression of both biocatalysis and glycoarray technologies will reduce commercialisation barriers both in terms of commercial glycan production and 'first in the market' glycan array companies
Matthew Gibson awarded an ERC Starting Grant
Dr. Matthew Gibson has been awarded a prestigious ERC (European Research Council) starting grant, with a value of €1.5 million. These grants are highly competitive and awarded on the basis of science excellence, rather than any targetted research field. Starter grants of for young academics within 7 years of completing their PhD. This grant will accerate the Group's work in the field of Antifreeze GlycoProtein (AFGP) Mimics. In particular, the GibsonGroup have pioneered the use of synthetic polymers as mimics of AFGPs, showing that they are capable of controlling ice crystal growth- The growth of ice is a huge problem in the cryostorage of donated cells and tissues, limiting their availabilty for transplantation and regenerative medicine.
There will be several PhD and Postdoctoral vacanices associated with this.
Work highlighted on Leverhulme Trust Website
A recent collaborative project grant between Gibson and Notman is highlighted on the Leverhulme Trust's webpage.
URSS funds awarded
We have received funding from the URSS to allow an undergraduate student to join us over the summer.