EPSRC-funded Workshop

Workshop on Indistinguishability and Model Discrimination in Systems Biology

Tuesday 29 September 2009

University of Warwick

As part of an EPSRC-funded grant on Indistinguishability analysis for model discrimination in Systems Biology: A Feasibility Study applied to Bacterial Peptidoglycan Biosynthesis a team from the School of Engineering, Biological Sciences and Chemistry held a one day workshop on the applicability of (structural) identifiability and indistinguishability to mechanism discrimination and identification in Systems Biology.

Programme

9.30 - 10.00	Coffee/Tea
10.00 - 10.30	Introduction: Model discrimination in Systems Biology Mike Chappell (University of Warwick)
10.30 - 11.15	Parameter redundancy and identifiability Diana Cole (University of Kent Canterbury)
11.15 - 12.00	Uncovering the design principles of polyamine regulation: An integrated modelling and experimental study Svetlana Amirova (University of Leicester)
12.00 - 13.15	LUNCH
13.15 - 14.15	Challenges for mathematical modelling in the drug industry James Yates & Chris Taylor (AstraZeneca)
14.15 - 14.45	Observable normal form for mechanism discrimination Neil Evans (University of Warwick)
14.45 - 15.15	Tea/Coffee
15.15 - 15.45	Bacterial peptidoglycan biosynthesis Dave Roper (University of Warwick)
15.45 - 16.15	Structural identifiability of two substrate enzyme catalyzed reaction mechanisms Daniel Bearup (University of Warwick)
16.15 - 16.45	The application of structural and numerical identifiability to Mur C kinetic models John Hattersley (University of Warwick)
16.45 - 17.00	CLOSE