Trials in follow up
These trials are closed to recruitment but observations on the effects of the intervention and data collection are ongoing.
Trials in follow up
| Trial name | About the trial | Trial type | Chief Investigator |
| ADAPT SEPSISLink opens in a new windowLink opens in a new window | BionmArker-guided Duration of Antibiotic treatment in hospitalised PaTients with suspected Sepsis: the ADAPT-Sepsis Trial | Emergency and Critical Care | Prof Paul D |
| AIR Main | UK study of ankle fracture rehabilitation – multicentre randomised controlled trial |
Surgery, Trauma & Orthopaedics |
Prof Rebecca Kearney |
| ALIFE2Link opens in a new window | Anticoagulants for LIving FoEtuses in women with recurrent miscarriage and inherited thrombophilia | Reproductive health | Prof Siobhan Quenby |
| ARTemis | Determining whether the addition to neo-adjuvant chemotherapy of an anti-angiogenic agent bevacizumab is more effective than standard chemotherapy alone in terms of short-term and long-term outcome in women presenting with HER2-negative early breast cancer. | Cancer | Prof Helena Earl |
|
Acute Rehabilitation following Traumatic anterior shoulder dISlocAtioN (ARTISAN): A Multi Centre Randomised Controlled Trial |
Surgery, Trauma & Orthopaedics |
Prof Rebecca Kearney |
|
| Big BabyLink opens in a new window |
Induction of labour for predicted macrosomia - The 'Big Baby Trial' |
Maternal Health |
Prof Siobhan Quenby Prof Jason Gardosi |
| CermLink opens in a new window | Chronic Endometritis and Recurrent Miscarriage - The CERM trial | Maternity | Prof Siobhan Quenby |
| COMPRESS-RCTLink opens in a new window | A feasibility randomised controlled trial of mechanical chest compression devices for in-hospital cardiac arrest | Emergency and critical care | Dr Keith Couper |
| COMPRESS-SIM | A feasibility study of the use of a mechanical chest compression device for inhospital cardiac arrest |
Emergency and critical care | Dr Keith Couper |
| De-ESCALATELink opens in a new window | Determining the optimum treatment for patients with HPV+ OPSCC. | Cancer | Professor Hisham Mehanna |
| MAMMO-50Link opens in a new window | Mammographic surveillance in breast cancer patients aged 50 years or older. | Cancer | Prof Janet Dunn |
| Neo-escape | A trial looking at chemotherapy before and after surgery for advanced peritoneal cancer | Cancer | Prof Chris Poole |
| PACKMaN |
Paramedic Analgesia Comparing Ketamine and MorphiNe in trauma |
Emergency and critical care | Prof Gavin Perkins
Dr Michael Smyth |
| PARAMEDIC-3 |
The PARAMEDIC-3 trial is looking at the most effective way to treat someone when their heart suddenly stops working out of hospital by giving drugs through a vein or into the bone. Answering this question will help to improve future treatment of people who have a cardiac arrest. |
Emergency and critical care | Prof Gavin Perkins |
| Persephone | Comparing six months Herceptin® treatment with twelve months, in patients with early stage breast cancer. | Cancer | Prof Helena Earl |
| POSED | A feasibility study of Prehospital Optimal Shock Energy for Defibrillation (POSED) | Emergency Care |
Prof Gavin Perkins |
| REGARD |
A Feasibility Randomised Controlled Trial to compare REgional versus General Anaesthesia in Reducing Delirium in patients with Hip Fractures |
Emergency and Critical Care |
Dr Joyce Yeung |
| RESPECTLink opens in a new window | To determine, in adults admitted to acute NHS hospitals, how, when and why are emergency care and treatment plans made and what effects do they have on patient care? | Emergency and critical care | Prof Gavin Perkins |
| SPHERe | Supervised Pulmonary Hypertension Exercise Rehabilitation (SPHERe) trial | Rehabilitation | Dr Gordon McGregor |
| STRESS-LLink opens in a new window | Stress-L: STudy into the REversal of Septic Shock with Landiolol (Beta Blockade) | Emergency and Critical Care | Dr Tony Whitehouse |
| TEAMM | Assessing the benefit of antibiotic prophylaxis and its effect on healthcare associated infection | Cancer |
Prof Mark Drayson |
| VITAL | Volatile vs Total intravenous Anaesthesia for major non-cardiac surgery | Perioperative trial | Dr Joyce Yeung |