Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge: a randomised controlled assessor-blind clinical and cost-effectiveness trial with internal pilot

People treated in intensive care need a great deal of special care and support. After discharge from hospital, some people find their muscles are still weak and their ability to exercise and to do everyday things may still be affected. They can also have confused memories of their time in the intensive care unit. For most people, these problems get better on their own, but for other people, they may continue for a long time after leaving hospital. iRehab will investigate the effects of:

1. 1. A six week multicomponent, rehabilitation intervention, delivered remotely by a core intervention team. In brief, the intervention includes four components: weekly symptom management; targeted exercise; psychological support and information/peer support.
   2. Compared to Standard Care, not involving structured rehabilitation.

Sample Size: 428 participants (control n=197; intervention n=231)

Primary outcome is health related quality of life at 8 weeks post randomisation. Secondary outcomes include health-related QoL (at six months), physical function, fatigue, anxiety and depression, healthcare resource use at eight weeks and six months post-randomisation

Trial Duration: 1st January 2022- 31st December 2024 (36 months)

 

Chief Investigator:

Dr Brenda O'Neill

Co-Chief Investigator:

Prof Danny McAuley

Sponsor:

Ulster University

Funder:

NIHR

Registration Number:

ISRCTN11266403

Enquiries:

Please direct all enquiries to the iRehab team;

Kerry Raynes: Trial Manager

Sarah Lowe, Trial Manager

Katherine Jones, Research Fellow

Email: iRehab@warwick.ac.uk

Tel: 02476151367