Motorization of Centrosome Separation
Hosted by Andrew McAinsh's lab, this is a cell culture and microscopy project experiment to investigate how centrosomes move the opposite poles of a cell during mitosis. It aims to answer questions such as: do the centrosomes move independently of each other? If not then how are they directed to the cell poles?
We found that centrosomes separate discontinuously. After nuclear evelope breakdown they move towards each other and apart, equilibrating to their spindle pole locations.
Here is a presentation I gave to the CMCB about this project.