Potential of a Multiscale Composite Platform for delivery of natural actives for topical applications

From acute wounds to diseases -such as psoriasis or dermatitis- the skin is subjected to numerous biological and pathophysiological situations in which pro-oxidant and antioxidant reactions must be precisely controlled, since the excess of reactive oxygen species (ROS) tends to be related to inflammatory processes. In some skin diseases -such as chronic wounds-, microbial infections can also appear, which very often degenerate into the development of a microbial biofilm, thus delaying the natural healing process of the skin. In this talk we will focus on the use of some natural actives with antioxidant, anti-inflammatory and antimicrobial properties and their formulation in a multi-scale administration platform to explore their potential for topical dermal applications.