Overview

My research interests include metal complexes and their applications in cancer treatment.

I have completed an M.Sc. in Scientific Research and Communication at the University of Warwick. Under the direction of Professor Peter Sadler, I undertook a research project entitled, 'Photoactivatable Platinum Complexes and their Applications in Photodynamic Therapy'. Graduating in July 2016, I completed a B.Sc. in Chemistry at Manchester Metropolitan University achieving 1st class honours. Under the direction of Dr Ryan Mewis, I conducted a research project entitled, “Synthesis of Bismuth Complexes for Radioimmunotherapy”.

Academic Background

2016 - 2017: M.Sc. (Hons), Scientific Research and Communication (Merit), University of Warwick

Research Project: Photoactivatable Platinum Complexes and their Applications in Photodynamic Therapy (PDT)

Supervisors: Professor Peter J. Sadler

Description: A series of novel platinum(II) Schiff base complexes were synthesised bearing electron withdrawing / donating substituents (R = fluorine, methyl or hydrogen) to investigate their inductive effects on UV-visible light absorbance, phosphorescence emission and their efficiency for singlet oxygen production. Emission intensities were also assessed in glycerol/water solutions of varying viscosities to mimic the intracellular environment. They were fully characterised using NMR spectroscopy and mass spectrometry. DFT calculations were also completed to investigate the complexes structural properties. Two of the complexes displayed properties suited for use in PDT and were suggested for further biological and photobiological testing.

Modules: During my M.Sc., I built on my interests of anticancer research and inorganic chemistry by undertaking a selection of advanced synthetic chemistry, biomedical research and microscopy and imaging modules to broaden my expertise in these areas. I also completed advanced communication modules in Centre for Applied Linguistics which focussed on writing scientific reports and articles as well as communicating my findings to various audiences. Part of this involved spending time at the BBC where I gained experience in using a range of media to communicate science which included newspaper, web, radio and TV. Using this experience and my own scientific knowledge I was able to plan and run a mini scientific symposium on cancer research while filming the entire process with the footage being edited it into a watchable video package.

2012-2016: B.Sc. (Hons), Chemistry (1st Class Honours), Manchester Metropolitan University

Research Project: Synthesis of Bismuth Complexes and their Applications in Radioimmunotherapy

Supervisor: Dr Ryan Mewis

Description: This involved the synthesis of a novel tetra-aza macrocycle complex which was coordinated to bismuth(III). The complex was fully characterised using NMR spectroscopy and mass spectrometry. The choice of pendant arms was thought to affect the stability and water solubility of the complex which in turn influences the potential efficacy. Theoretically, the complex could then be conjugated to an antibody that targeted specific cancers.

Modules: Throughout the course of my B.Sc. I studied fundamental chemistry concepts in a number of areas. This involved inorganic and organic synthesis, analytical and spectroscopic techniques, physical and quantum chemistry and modern industrial chemistry. I also completed modules in natural resources and pollution.

Extracurricular

I enjoy studying martial arts and have been a practitioner of Muay Thai, Boxing and Taekwondo throughout my life. I have competed in various competitions in these styles with my most notable achievements being the recipient of a gold medal in the 2016 British University Taekwondo League and a winning competitor in the 2016 MMU Fight Night 2 which helped raise over £2000 for Wood Street Mission charity. I also have completed other charitable sporting events which include the 2013 Tough Mudder assault course in aid of Help for Heroes charity and the 2011 Cardiff Half Marathon in aid of Barnardo’s charity.