Please Note: Caroline is on maternity leave until 1st March 2022
Caroline completed her GCSEs (2003-2005) and A-levels (2005-2007) in her home town of Bristol, before moving to the West Midlands to undertake her Chemistry degree at the University of Warwick. In July 2011 she graduated with a 1st Class Honours MChem in Chemistry with Medicinal Chemistry with Professional Experience.
During the second year of her degree (2009) Caroline undertook a Nuffield Foundation funded summer project at The University of Warwick entitled, “Exploring the biomaterial interface: what classes of protein are repelled by tertiary amine oxide surfaces?” and supervised by Dr Andrew Marsh.
The following year (April- June 2010) Caroline traveled to the University of Tasmania in Australia, in order to obtain international research experience. Her project, “Investigating aspects of the total synthesis of thaxtomins and thaxtomin derivatives,” was supervised by Dr Jason Smith.
Caroline’s MChem project (2010- 2011), “Biomimetic glycopeptides for biomineralisation”, was undertaken in the Gibson group, where she remained to carry out her PhD. Caroline's PhD was entitled "Biointegrative Polymer Surfaces". The project spanned the Chemistry-Life Science interface and included thermoresponsive polymers, surface modification and characterisation (quartz-crystal microbalance, contact angle measurements, ellipsometry, XPS), carbohydrate immobolisation and binding, protein binding and host-pathogen responses. In addition to her PhD, Caroline also completed The Warwick Postgraduate Certificate in Transferable Skills and chose to focus on modules in academic scientific writing and project management.
Caroline is currently studying novel compounds for ice recrystallisation inhibition and nucleation.
 Alexander N. Baker, Sarah-Jane Richards, Sarojini Pandey, Collette S. Guy, Ashfaq Ahmad, Muhammad Hasan, Caroline I. Biggs, Panagiotis G. Georgiou, Alexander J Zwetsloot, Anne Straube, Simone Dedola, Robert A. Field, Dimitris Grammatopoulos, Neil R Anderson, Marc Walker, Matthew I. Gibson, M.I., "A Glycan-based Flow-Through Device for the Detection of SARS-COV-2" ACS Sensors,2021, Accepted
 Angela Casillo, Antonio Fabozzi, Irene Russo Krauss, Ermenegilda Parrilli, Caroline I. Biggs, Matthew I. Gibson, Rosa Lanzetta, Marie-Sousai Appavou, Aurel Radulescu, Maria L. Tutino, Luigi Paduano and Maria M. Corsaro, "Physicochemical Approach to Understanding the Structure Conformation, and Activity of Mannan Polysaccharides", Biomacromolecules, 2021, 2, 1445-1457
 Laura E. Wilkins, Muhammad Hasan, Alice E. R. Fayter, Caroline I. Biggs, Marc Walker and Matthew I. Gibson, "Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles", Polymer Chemistry, 2019, 10, 2986-2990
 Benjamin Martyn, Caroline I. Biggs, and Matthew I. Gibson, "Comparison of systematically functionalized heterogeneous and homogenous glycopolymers as toxin inhibitors", Journal of Polymer Science Part A: Polymer Chemistry, 2019, 57, 40-47
 Nicholas Vail, Christopher Stubbs, Caroline I. Biggs and Matthew I. Gibson, "Ultra-Low Dispersity Poly(vinyl alcohol) Reveals Significant Dis-persity Effects on Ice Recrystallization Inhibition Activity", ACS Macro Letters, 2017, 6, 1001–1004
 Antonio Laezza, Angela Casillo, Sandro Cosconati, Caroline I. Biggs, Antonio Fabozzi, Luigi Paduano, Alfonso Iadonisi, Ettore Novellino, Matthew I. Gibson, Antonio Randazzo, Maria M. Corsaro, and Emiliano Bedini, "Decoration of Chondroitin Polysaccharide with Threonine: Synthesis, Conformational Study, and Ice-Recrystallization Inhibition Activity," Biomacromolecules, 2017, 18 (8), 2267–2276
 Caroline I. Biggs, Christopher Packer, Steven Hindmarsh, Marc Walker, Neil. R. Wilson,
Jonathan P. Rourke and Matthew I. Gibson, "Impact of Sequential Surface-Modification of Graphene Oxide on Ice Nucleation", Physical Chemistry Chemical Physics, 2017, 19, 21929-21932
 Nga Sze Ieong, Caroline I. Biggs, Marc Walker and Matthew I. Gibson, "Comparison of RAFT derived Poly(vinylpyrolidone) verses Poly(oligoethyleneglycol methacrylate) for the Stabilization of Glycosylated Gold Nanoparticles", Journal of Polymer Science, Part A, 2017, 55(7), 1200-1208
 Caroline I. Biggs, Marc Walker and Matthew I. Gibson, ‘Grafting to’ of RAFTed Responsive Polymers to Glass Substrates by Thiol-Ene and Critical Comparison to Thiol-Gold Coupling, Biomacromolecules, 2016, 17 (8), 2626–2633
 Sarah-Jane Richards, Caroline I. Biggs and Matthew I. Gibson. Methods in Molecular Biology; Macro-Glycoligands, Series Vol 1367 "Multivalent Glycopolymer-coated Gold Nanoparticles", 2016, e-book ISBN 978-1-4939-3130-9, Hard Cover ISBN 978-1-4939-3129-3
Caroline is passionate about outreach work and is a STEM Ambassador. In particular, she enjoys working to increase the number of pupils from under-represented backgrounds progressing to highly-selective universities.
She works as a tutor for the Brilliant Club, where she designs and delivers programmes of academic enrichment tutorials, based on aspects of her research, to state school pupils. She is also a Realising Opportunities academic tutor, working to support the progression of talented students to leading research intensive universities. Additionally, she works collaboratively with the Brilliant Club and the University of Warwick's UniTracks program to deliver e-tutorials to pupils in less accessable, rural locations. More details about Caroline's outreach teaching can be found below.
Midlands Young Researcher Meeting on Nanomaterials, The University of Warwick, 17/10/2015. A one day meeting, funded by the RSC Materials Division, bringing together PhD students and early career researchers from the Universities of Warwick, Nottingham, Loughborough, Liverpool and Bristol and industrial chemists.
- International Carbohydrate Conference, New Orleans, USA (17/07/16 - 21/07/16)
- COST MultiGlycoNano Conference, Antalya, Turkey (28/10/2015- 31/10/2015)
- Division of Carbohydrate Chemistry, 250th ACS National Meeting, Boston, Massachusetts, USA (16/08/2015 - 20/08/2015)
- Division of Colloid and Surface Chemistry, 250th ACS National Meeting, Boston, Massachusetts, USA (16/08/2015 - 20/08/2015)
- COST MultiGlycoNano Training School, Bangor University, Wales, UK (09/04/15 - 11/04/15)
- RSC Carbohydrate Group Autumn Meeting, The University of Warwick, Coventry, UK (08/09/14 - 09/09/14)
- BBSRC Midlands Symposium, The University of Warwick, Coventry, UK (01/09/14 - 02/09/14)
- Department of Chemistry Postgraduate Symposium, The University of Warwick, Coventry, UK (28/05/14)
- Summer Course Glycosciences (13th European Training Course on Carbohydrates), Wageningen, The Netherlands (13/04/14 - 17/04/14). Oral presentation awarded as the first place poster prize.
- School of Life Sciences Postgraduate Symposium, The University of Warwick, Coventry, UK (24/03/14 - 26/04/14)
- Advanced Polymers via Macromolecular Engineering (APME), Ghent, Belgium (21/05/17 - 25/05/2017)
- Symposium on Nanoscience and Nanotechnology, The University of Birmingham, UK (13/12/2016)
- Warwick Polymer 2016, University of Warwick, Coventry, UK (11/07/16 - 16/07/16)
- 12th International Conference on Materials Chemistry (MC12), York University, UK (20/07/15 - 24/07/15)
- COST MultiGlycoNano Training School, Bangor University, Wales, UK (09/04/15 - 11/04/15)
- Emerging Nanomaterials for Healthcare, University of Warwick, Coventry, UK (28/10/14)
- BBSRC CEO Visit, University of Warwick, Coventry, UK (10/11/14)
- BBRSC Midlands Symposium, University of Warwick, Coventry, UK (01/09/14 - 02/09/14)
- Division of Carbohydrate Chemistry, 248th ACS National Meeting, San Francisco, California, USA (09/08/14 - 14/08/14)
- Macro Group UK Young Researchers' Meeting, Durham University, UK (24/07/14 - 25/07/14)
- RSC Younger Members Symposium, The University of Birmingham, UK (24/06/14)
- Summer Course Glycosciences (13th European Training Course on Carbohydrates), Wageningen, The Netherlands (13/04/14 - 17/04/14)
RSC Chemical Biology Conference, University of Warwick, Coventry, UK (01/04/14)
- First Annual Polymer Club Symposium, University of Warwick, Coventry, UK (02/09/13)
- 10th IUPAC International Conference on Advanced Polymers via Macromolecular Engineering, Durham University, UK (18/08/13 - 22/08/13)
- 11th International Conference on Materials Chemistry (MC11), University of Warwick, Coventry, UK (08/07/13 - 11/07/13)
- School of Life Sciences Postgraduate Symposium, The University of Warwick, Coventry, UK (18/03/13 - 20/03/13)
- RSC/ Biochemical Society Carbohydrate Group Younger Members Meeting, Burlington House, Royal Society of Chemistry, London, UK (11/03/13)
- RSC Biomaterials Chemistry Group 7th Annual Meeting, Sheffield Hallam University, Sheffield, UK (08/01/13 - 09/01/13)
- RSC Postgraduate Symposium on Nanotechnology, University of Birmingham, Birmingham, UK (14/12/12)
- Warwick Polymer 2012, University of Warwick, Coventry, UK (09/07/12 - 12/07/12)
- First place poster prize awarded at the Symposium on Nanoscience and Nanotechnology 2016 (Birmingham, UK)
- First place poster prize awarded at the Summer Course Glycosciences 2014 (Wageningen, The Netherlands)
- Third place poster prize awarded at the Macro Group UK Young Researchers' Meeting 2014 (Durham, UK)
Grants and Bursaries
- RSC Materials Chemistry Division Award (£800) to support attendence at the International Carbohydrate Symposium 2016 in New Orleans, USA
- RSC Small Grants for Scientific Activities (£500) awarded by the RSC Materials Division to support the running of the Midlands Young Researcher Meeting on Nanomaterials at The University of Warwick
- RSC Materials Chemistry Division Award (£800) to support attendence at the 250th ACS National Meeting in Boston, USA
- RSC Travel Grant (£150) to support attendence at the MC12 conference in York
- COST/ IBCarb funding (£400) to support attendence at the COST MultiGlycoNano Training School in Bangor
- Macrogroup DH Richards Bursary (£250), to support attendance at the Summer Course Glycosciences 2014 in The Netherlands
- RSC Chemical Biology Interface Division Travel Grant (£200), to support attendance at the Summer Course Glycosciences 2014 in The Netherlands
Caroline wins the first place poster prize at the Symposium on Nanoscience and Nanotechnology, 2016
Caroline wins the first place poster prize at the Summer Course Glycosciences, 2014
Caroline wins third place poster prize at the Macro Group Young Researchers' Meeting, 2014
Caroline's Brilliant Club Handbooks, designed to support the students in learning about her research. "Polymers: from plastic bags to heathcare diagnostics" for Year 12 pupils (age 16-17). This course has been delivered to pupils at Painsley Catholic College, Barking Abbey School and King Edward VI Sheldon Heath Academy.
"Can we freeze a human?" for Year 10 (age 14-15) pupils. This course has been delivered to pupils at Bartley Green School, Wood Green Academy, Barr Beacon School and through on-line tutorials to pupils in a selection of Coventry Schools.
"How Many Engineers does it take to make an ice cream" course designed by UCL engineering department and delivered by Caroline to Year 6 (age 10-11) pupils at Old Park Primary in Telford.
The University of Warwick
Chemistry with Medicinal Chemistry with Professional Experience, 1st Class Honours, 2007-2011
Chemistry (Biointegrative Polymer Surfaces), 2011-2015
Lab: 1.05/1.07 (MAS)
Address: Department of Chemistry, University of Warwick, Coventry, CV4 7AL
Orcid ID: Orcid.org/0000-0002-8007-3132