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Huilin Li

PhD Student,
FT-ICR MS Group
Department of Chemistry
The University of Warwick
Millburn Hill Road
Coventry CV4 7AL, UK
Office: +44 (0) 24 7615 1304
Lab: +44 (0) 24 7615 1305
Email: Huilin.Li@warwick.ac.uk


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PUBLICATIONS:

 

  • Huilin Li, Jonathon R. Snelling, James H. Scrivens, Peter J. Sadler, Peter B. O’Connor. Mass Spectrometric Strategies to Improve the Identification of Pt(II)-modification Sites on Peptides and proteins. Submitted to Anal. Chem. 2012.

  • Huilin Li, Peter B. O'Connor. Electron Capture Dissociation of Disulfide, Sulfur-Selenium, and Diselenide Bound Peptides. J. Am. Soc. Mass Spectrom. 2012, DOI: 10.1007/s13361-012-0473-0.
  •  Huilin Li, Stephen A. Wells, J. Emilio Jimenez-Roldan, Rudolf A. Römer, Yao Zhao, Peter J. Sadler, Peter B. O'Connor. Protein Flexibility is Key to Cisplatin Cross-linking in Calmodulin. Protein Sci. 2012, 21, 1269-1279.
  • Yulin Qi, Mark P. Barrow, Huilin Li, Joseph E Meier, Steve L. Van Orden, Christpher J. Thompson, and Peter B O'Connor. Absorption-mode: The Next Generation of Fourier Transform Mass Spectra. Anal. Chem. 2012, 84, 2923-2929.

  • Hui Zhou, Huilin Li, Zhong Zheng, Fengrui Song, Junpeng Xing, Zhiqiang Liu, Shuying Liu. Screening for alpha-glucosidase inhibitors from coptidis-rehmanniae herb couple by using ultrafiltration liquid chromatography/mass spectrometry. J. Liq. Chromatogr. Related Technol. 2012, 35, 1-14.

  • Huilin Li, Tzu-Yung Lin, Steve L. Van Orden, Yao Zhao, Mark P. Barrow, Ana M. Pizarro, Yulin Qi, Peter J. Sadler, Peter B. O'Connor. Use of Top-down and Bottom-up Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Mapping Calmodulin Sites Modified by Platinum Anticancer Drugs. Anal. Chem., 2011, 83 (24), 9507-9515.
  • Yulin. Qi, Steve L. Van Orden, Christpher J. Thompson, Mark P. Barrow, Huilin. Li, Pilar. Perez-Hurtado,and Peter B O'Connor. Variation of the Fourier Transform Mass Spectra Phase Function with Experimental Parameters. Anal. Chem. 2011, 83 (22), 8477-8483.
  • Huilin Li, Yao Zhao, Hazel I. A. Phillips, Yulin Qi, Tzu-Yung Lin, Peter J. Sadler, Peter B. O'Connor. Mass spectrometry evidence for cisplatin as a protein cross-linking reagent. Anal. Chem. 2011, 83 (13), 5369-5376.
  • Wenlong Liu, Shu Liu, Huilin Li, Fengrui Song, Zhiqiang Liu, Shuying Liu. Binding of Alpha 1-acid glycoprotein with aconitum alkaloids: an investigation by IF-MALDI-FT-MS. Rapid Commun. Mass Spectrom. 2011, 25, 973-978.
  • Shu Liu, Jun Yan, Huilin Li, Fengrui Song, Zhongying Liu, Zhiqiang Liu, Shuying Liu. Studies on Chemical Constituents of Compound Indigowoad Root Granule by Mass Spectrometry. Chem. J. Chinese U. 2010, 31(6), 1137-1142.
  • Huilin Li, Fengrui Song, Junpeng Xing, Zhiqiang Liu, Shuying Liu. Screening and structures characterization of alpha-glucosidase inhibitors from hawthorn leaves flavonoids extract by Ultrafiltration LC-DAD-MSn and SORI-CID FT ICR MS. J. Am. Soc. Mass Spectrom. 2009, 20 (8), 1496-1503.
  • Xiangyu Meng, Huilin Li, Fengrui Song, Chunming Liu, Zhiqiang Liu, Shuying Liu. Studies on triterpenoids and flavones in Glycyrrhiza uralensis Fisch. by HPLC-ESI-MSn and FT-ICR-MSn. Chinese J. Chem. 2009, 27 (2), 299-305.
  • Huilin Li, Fengrui Song, Zhong Zheng, Zhiqiang Liu, Shuying Liu. Characterization of Oligsaccharides and Phenolid Acids in the Cinese Herb Tanshen by ESI-FT ICR MS. J. Mass Spectrom. 2008; 43: 1545-1552.
  • Hao Yue, Zifeng Pi, Huilin Li, Fengrui Song, Zhiqiang Liu and Shuying Liu. Studies on the Stability of Diester-diterpenoid Alkaloids from the Genus Aconitum L. by High Performance Liquid Chromatography Combined with Electrospray Ionisation Tandem Mass Spectrometry (HPLC/ESI/MSn). Phytochem. Anal. 2008; 19: 141-147.
  • Yue Liu, Zhiqiang Liu, Huilin Li, Fengrui Song, Shuying Liu. Studies on Diterpenoids Constituents from Euphorbia Kansui by Electrospray Ionization Multi-stage Tandem Mass Spectrometry. Chem. J. Chinese U. 2008, 29(9): 1727-1735.
  • Xiaoyan Qiu, Meng Cui, Huilin Li, Zhiqiang Liu and Shuying Liu. Prompt disulfide fragmentations of disulfide-containing proteins in a matrix-assisted laser desorption/ ionization source. Rapid Commun. Mass Spectrom.2007; 21: 3520-3525.
  • Yufeng Zhao, Fengrui Song, Hao Yue, Xinhua Guo, Huilin Li, Zhiqiang Liu, Shuying Liu. Deoxyaconitine of Metabolite of Aconitine by Human Intestinal Bacteria and Electrospray Ionization Tandem Mass Spectrometry. Chem. J. Chinese U. 2007, 28(11): 2051-2055.
  • Hongjuan Dong, Zhiqiang Liu, Fengrui Song, Zhan Yu, Huilin Li, Shuying Liu. Structural analysis of monoterpene glycosides extracted from Paeonia lactiflora Pall. using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry and high-performance liquid chromatography/ electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2007; 21: 3193-3199.
  • Shumin Wang, Huilin Li, Zhiqiang Liu, Shuying Liu, Bemlian Cui. Studies on the Contents of Catechin and Epicatechin in Catechu by HPLC, Lishizhen Medicine and Materia Medica Research. 2006, 17(4): 490-491.
  • Hongjuan Dong, Zhiqiang Liu, Fengrui Song, Zhan Yu, Huilin Li, Shuying Liu. Studies on Paeoniflorin by Electrospray Ionization Tandem Mass Spectrometry. Chem. J. Chinese U. 2006,27(11): 2066-2069.
  • Huilin Li, Junpeng Xing, Zhiqiang Liu, Shuying Liu. Analysis of Cephalosporins by Electrospray Ionization Multi-stage Tandem Mass Spectrometry. J. Chin. Mass Spec. Soc. 2005, 26(4): 198-202.

 

PRESENTATIONS:

 

  • Huilin Li, Stephen A. Wells, J. Emilio Jimenez-Roldan, Rudolf A. Römer, Yao Zhao, Peter J. Sadler, Peter B. O'Connor. Protein Flexibility is Key to Cisplatin Cross-linking in Calmodulin (Talk). 19th International Mass Spectrometry Conference, Kyoto, Japan. 15-21 Sep., 2012.
  • Huilin Li, Stephen A. Wells, J. Emilio Jimenez-Roldan, Rudolf A. Römer, Yao Zhao, Peter J. Sadler, Peter B. O'Connor. Protein Flexibility is Key to Cisplatin Cross-linking in Calmodulin (Talk). 10th European FTMS workshop, Warwick, UK. 1-5 April, 2012.
  • Huilin Li, Tzu-Yung Lin, Steve L. Van Orden, Yao Zhao, Ana M. Pizarro, Peter J. Sadler, Peter B. O'Connor. Mapping the Binding Sites of Platinum Anticancer Drug-Cisplatin to Calmodulin. 32nd BMSS Conference, Cardiff, UK, Sep. 11-14, 2011.
  • Huilin Li, Tzu-yung Lin, Ana Pizarro, Peter J. Sadler, Peter B. O'Connor. Mapping the binding Sites of Platinum Anticancer drugs to Calmodulin. 59th ASMS Conference on Mass Spectrometry and Allied Topics. Denver, CO, June 5-9, 2011.
  • Huilin Li, Yao Zhao, Hazel I. A. Phillips, Yulin Qi, Peter J. Sadler, and Peter B. O'Connor. Mass spectrometry evidence for cisplatin as a cross-linking reagent (Poster). 8th UppCon Conference on Electron Capture and Transfer Dissociation. Villars-sur-Ollon, Switerland, Feb. 6-10, 2011
  • Huilin Li, Yao Zhao, Hazel I. A. Phillips, Yulin Qi, Peter J. Sadler, and Peter B. O'Connor. Mass spectrometry evidence for cisplatin as a cross-linking reagent (Poster). 8th UppCon Conference on Electron Capture and Transfer Dissociation. Villars-sur-Ollon, Switerland, Feb. 6-10, 2011
  • Huilin Li, Fengrui Song, Zhiqiang Liu, Shuying Liu. Characterization of Oligsaccharides and Phenolid Acids in the Cinese Herb Tanshen by ESI-FT ICR MS. (Oral Presentation). The 12th International Beijing Conference and Exhibition on Instrumental Analysis (12th BCEIA). Oct. 18-21, 2007
  • Huilin Li, Junpeng Xing, Fengrui Song, Zhiqiang Liu, Shuying Liu. Characterization of tanshinones extracted from Salvia miltiorrhiza bunge by supercritical fluid extraction with HPLC/PDA/ESI-MS, HPLC-MSn and FT-ICR MS (Poster). 16th National Symposium and Exhibition on Chromatography &1st Dalian International Symposium and Exhibition on Chromatography ( NISEC ). June 4 - 6, 2007
  • Huilin Li, Junpeng Xing, Fengrui Song, Zhiqiang Liu and Shuying Liu Fragmentation pathways of Tanshinones by ESI-FT-ICR-MS (Poster). The 11th International Beijing Conference and Exhibition on Instrumental Analysis (11th BCEIA). Oct. 20-23, 2005
 

AWARDS:

  • Travel Award for the 25th Lake Louise Tandem Mass Spectrometry Workshop, Lake Louise, Alberta, Canada. Nov. 28 to Dec. 1, 2012.

  • Warwick Postgraduate Research Scholarship (WPRS). 2009-2012
  • University of Warwick Departmental Studentships. 2009-2012
  • IMSF Travel Grant for the 19th International Mass Spectrometry Conference. Kyoto, Japan, Sep. 15-21, 2012.
  • BMSS Travel Award for the 59th ASMS Conference on Mass Spectrometry. Denvor, CO, USA. Jun. 5-9, 2011.
  • Travel Award for the abstract competition at the 8th UppCon Conference on Electron Capture and Transfer Dissociation. Villars-sur-Ollon, Switerland, Feb. 6-10, 2011.