Welcome to the OSS Lab
Headed by Orkun S. Soyer, the current focus of the OSS lab is to develop a predictive and quantitative understanding of cellular metabolism and metabolic interactions among cells.
Current key areas of research
1. Emergence and evolution of metabolic excretions and interactions in microbes (funded by NSF/BBSRC) (in collaboration with Wenying Shou).
2. Feedbacks between metabolism at cell level and spatial organisation at population level (funded by Gordon and Betty Moore Foundation).
3. Electrical control of cellular metabolism (funded by Cancer Research UK) (in collaboration with Pat Unwin).
4. Deciphering microbial interactions in microbial communities using temporal metagenomics (currently in-between funding) (in collaboration with Christopher Quince).
See also our past projects on anaerobic microbial communities: Engineering Synthetic Microbial Communities for Biomethane Production and Monitoring UK Anaerobic Digestion Microbiomes.
Book Chapter (August 2021)
'An Evolutionary Systems Biology View on Metabolic System Structure and Dynamics' by Johnson C., Delattre H., Hayes C., Soyer O.S. In: Crombach A. (eds) Evolutionary Systems Biology. Link
New Publication (July 2021)
'STRONG: metagenomics strain resolution on assembly graphs'. Quince, C., Nurk, S., Raguideau, S. Soyer OS et al. Genome Biol 22, 214. Link
Pre-Print news (July 2021)
'Novel microbial syntrophies identified by longitudinal metagenomics' by
OSS Lab Pre-Print (May 2021)
'Multi-site enzymes as a mechanism for bistability in reaction networks' by