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Welcome to the OSS Lab


Headed by Orkun S. SoyerLink opens in a new window, the current focus of the OSS lab is to develop a quantitative understanding of cellular metabolism and metabolic interactions among species.

On the former topic, we develop theoretical 'toy' models of key motifs in cell metabolism and conduct experimental analyses on single cell physiology in yeast and mammalian cells. On the latter topic, we create model ('synthetic') microbial communities and study species co-existence and interactions in these. These efforts currently focus on a 15-species cyanobacterial microbial community that develops extensive spatial organisation.

For additional information please see our ResearchLink opens in a new window, PublicationsLink opens in a new window, and Pre-PrintsLink opens in a new window pages. You can access code/software from our GitHubLink opens in a new window page and we have started to use Protocols.ioLink opens in a new window to make our lab protocols easily available (more will be added over the next few months).

Teaching and Outreach

We are currently involved in undergraduate teaching with thought modules focussing on 'Dynamics of Cellular Systems' and 'Synthetic Biology'. We have also contributed to an open book project on Economic Principles in Cell BiologyLink opens in a new window with a chapter focusing on 'Dynamics of Cellular Metabolism'.

We occasionally participate in Outreach and Social Science linked projects with some examples available hereLink opens in a new window and hereLink opens in a new window.

Collaborative Initiatives

We are founding members of the Warwick Bio-Electrical Engineering Innovation Hub (BEE)Link opens in a new window and Warwick Aquatic Monitoring Station (WAMOS)Link opens in a new window. We have also led previous collaborative projects on anaerobic microbial communities focusing on Engineering Synthetic Microbial Communities for Biomethane ProductionLink opens in a new window and temporal metagenomics of AD reactors: Monitoring UK Anaerobic Digestion MicrobiomesLink opens in a new window.

In 2014 and 2022, we led the development of two residential meetings at the Isaac Newton Institute focusing on microbial communities. The full program and selected talks from these two meetings are available online at the INI website: 2014 Microbial Communities Link opens in a new windowand 2022 Microbial CommunitiesLink opens in a new window.

Our Funders

betty moore logo

BBSRC 2019 logo

CRUK logo

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Pint of Science public engagement event (May 2023)

Sarah captivated her audience at the recent Pint of Science event in Leamington spa, with her talk on 'Metabolic communications in a microbial macro-structure' as part of the 'What's in the Water?Link opens in a new window' series.

Bio-electrical engineering BBSRC showcase (April 2023)

We were excited to be involved with the recent BBSRC BEE showcaseLink opens in a new window that took place at the University of Warwick and brought together innovators, entrepreneurs, and investors working in the field of Bio-Electrical Engineering (BEE) for networking and knowledge exchange and to direct the development of future funding opportunities.

PhD Viva Success (April 2023)

Congratulations to Emily for smashing her PhD Viva. Best of luck in your new adventure Dr Skates!

Publication success (February 2023)

Visit eLifeLink opens in a new window to read our latest publication by West et al 'Dynamics of co-substrate pools can constrain and regulate metabolic fluxes'.

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