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Friday, October 28, 2022
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Life Sciences seminar by Dr Xuming ZhangIBRB 0.01, Gibbet Hill“Title: Molecular and Cellular Mechanisms of Pain” Pain is one of the most common medical conditions associated with many diseases. We aim to understand how pain is generated, transmitted and transitions to the chronic stage. To address these questions, we use a combination of molecular biology, electrophysiology, protein biochemistry, Ca2+ imaging, histology and pain behaviours. In the seminar, I will show our recent findings of the critical roles of two TRP ion channels, TRPA1 and TRPM2, in inflammatory pain, neuropathic pain and chronic arthritis pain and their regulation by scaffolding proteins and inflammatory signaling. |