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Background to my research

My background in Engineering

Looking back, I think I have always been an engineer, but it is only since returning to University that I have come to appreciate the distinct perspective that is provided by taking an engineering view of systems, from complex telecommunications networks to protein interactions within cells.

One amoung many early signs of my interest in engineering was my love of Lego, which included building a lego suspension bridge with a 5 foot centre span (Built in a pre-metric era).

I read Engineering at Cambridge, which included everything from control systems to thermodynamics, to quantum theory, to structures, to digital and analogue circuit design. It has been fascinating to see how elements from many of these topics have cropped up again in the MOAC MSc modules, my PhD and now my work as a research fellow. Sometimes they were slightly disguised, such as the parallels between engineering control systems and enzyme kinematics, sometimes the lectures within the MOAC course were a direct mirror of the lectures many years earlier.

After completing my engineering degree at Cambridge I then went to the BT research centre at Martlesham Heath where I soon became involved in the early development work on the System X telephone exchange.

When the work was transferred out of British Telecom I moved with it, working for Plessey at Taplow Court near Maidenhead. One of my projects was the design of the analogue and digital circuitry on an Integrated Circuit that was built by Plessey Semiconductors.

I then moved with Plessey to Liverpool, and finally in Coventry, continuing to work on System X and its successors. The company had by this time evolved into Marconi, which was bought by Ericsson, and in early 2007 I took the offer of voluntary redundancy in order to do 'something completely different', and ended up in MOAC.

Except that in some ways this was not completely different...

My long-standing interest in Biophysics

Soon after leaving university, I came across a picture of centriole, a cellular organelle. I immediately felt that its remarkable and enigmatic structure had little to do with biology, and a lot to do with with physics and engineering. This led in time to an interest in the way that vibrational modes within proteins might be linked to ways in which parts of the cell communicate with each other.

As I pursued this interest, I found myself bringing telecoms and engineering principles into my attempts to understand a little more about how cells work. One person I encountered early on, and whose ideas continue to fascinate and inspire me is Professor Herbert Fröhlich .

In the 1960’s Professor Fröhlich suggested that the way that proteins vibrate might be the key to understanding some of the ways that proteins interact, and might ultimately be the key to understanding some of the ‘big’ questions within biology, including possibly consciousness itself.

The progress of Fröhlich’s ideas has been slow, mainly because of the difficulty of doing experiments in this area. In 1999 I made contact with a company, Vermont Photonics in Vermont, USA who are developing equipment that might be of some use to verify Fröhlich’s idea’s. I been honoured to be included on their Scientific Advisory Board, along with people who are far more qualified to hold such a position, such as Lila Gierasch, from the dept of Biochemistry at the University of Massachusetts.

Application of the ideas to water under high electrical stress

More recently I have become aware that Fröhlich’s resonance hypothesis may have applications other than in biophysics. One of these relates to the behaviour of water when exposed to sudden electrical stress. The behaviour of water in this situation is about to be investigated in the Applied Water Physics theme within Wetsus. I therefore formed Coherent Water Systems which is now a member of the theme so that I would be able to be more fully involved in this research.