Professor Mark Wall

Supervisor Details

Contact Details

School of Life Sciences, University of Warwick

Scientific Background

Research Interests

I am a neuroscientist interested in measuring the electrical properties of neurons in the mammalian brain and how they change in conditions such as epilepsy, schizophrenia, and Alzheimer’s disease.

I am an electrophysiologist interested in neuronal and synaptic physiology in both health and disease. I use extracellular recording, FSCV and multiple patch-clamp recording to study synaptic transmission and the properties of neurons. I combine electrophysiology with computational analysis (in collaboration with Prof Magnus Richardson Warwick Mathematics) to measure the electrophysiological properties of neurons.

Current projects include investigation of neuronal function in models of epilepsy, schizophrenia, and neurodegeneration (AD and PD) and how neural circuits can be modulated by changes in the levels of carbon dioxide.

Scientific Inspiration

Dr GABA for discovering GABA.

Research Groups

Neuroscience

Supervision Style

In three words or phrases: supportive, goal-driven, collaborative.

Provision of Training

I prefer to take responsibility for your technical training at first, leading to more independence later. I will be available to help through-out your PhD and experienced post docs/PhD students will also be present for help.

Progression Monitoring and Management

I like to be kept up to date, and will expect to see evidence of method development/data generation results on a daily/weekly basis. I am here for advice and guidance to help you reach the goals you set for yourself.

Communication

I am happy to discuss any issues that are impacting your ability to fulfil your potential or my/our expectations.

PhD Students can expect scheduled meetings with me:

In a group meeting

At least once per week

In year 1 of PhD study

At least once per week

In year 2 of PhD study

At least once per week

In year 3 of PhD study

At least once per week

These meetings will be face to face, and I am usually contactable for an instant response on every working day.

Working Pattern

Work in my lab requires being present on site (be it in a laboratory or at a field site) during core hours (or a subset if working part time).

Notice Period for Feedback

I need at least 2 week’s notice to provide feedback on written work of up to 5000 words.

MIBTP Project Details

Current Projects (2025-26)

Co-supervisor on projects with Dr Marie Holt and Dr Xuming Zhang.

Previous Projects (2024-25)

Primary supervisor for:

Cerebral spinal fluid (CSF) tau as a biomarker for brain ageing – effects on neuronal and network function Defining the mechanism of action of protein aggregates on hippocampal microcircuit function

Co-supervisor on projects with Dr Marie Holt, Professor Bruno Frenguelli and Dr Xuming Zhang.