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Publications

See the Glossary for a description of commonly used terms and acronyms associated with the HAT projects.

Davis, CN, Keeling, MJ, Rock KS (2021). Modelling gambiense human African trypanosomiasis infection in villages of the Democratic Republic of Congo using Kolmogorov forward equations. MedRxiv [pre-print, not peer-reviewed]. Paper summaries: English, French

Aliee, M, Keeling, MJ, Rock, KS (2021). Modelling to explore the potential impact of asymptomatic human infections on transmission and dynamics of African sleeping sickness. MedRxiv [pre-print, not peer-reviewed]. Paper summaries: English, French
Davis, CN, Castaño, MS, Aliee, M, Patel, S, Miaka, EM, Keeling, MJ, Spencer, SEF, Chitnis, N, Rock, KS (2021). Modelling to quantify the likelihood that elimination of transmission has occurred using routine gambiense human African trypanosomiasis surveillance data. Clinical Infectious Diseases, ciab190. Paper summaries:
Aliee, M, Castaño, MS, Davis, CN, Patel, S, Miaka, EM, Spencer, SEF, Keeling, MJ, Chitnis, N, Rock, KS (2021). Predicting the impact of COVID-19 interruptions on transmission of gambiense human African trypanosomiasis in two health zones of the Democratic Republic of Congo. Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 115, Issue 3, March 2021, Pages 245–252. Paper summaries: English, French
Antillon, M, Huang, C, Rock, KS, Tediosi, F (2021). Economic evaluation of disease elimination: an extension to the net-benefit framework and application to human African trypanosomiasis. MedRxiv [pre-print, not peer-reviewed]. doi: 10.1101/2021.02.10.20181974. Paper summaries: English
Antillon, M, Huang, C, Crump, RE, Brown, P, Snijders, R, Miaka, EM, Rock, KS, Tediosi, F (2020). Economic evaluation of gHAT elimination campaigns in five distinct transmission settings in DRC. MedRxiv [pre-print, not peer-reviewed]. doi: 10.1101/2020.08.25.20181982. Paper summaries: English, French
Davis, C, Rock, KS, Antillón, M, Miaka, EM, Keeling, MJ (2021). Cost-effectiveness modelling to optimise active screening strategy for gambiense human African trypanosomiasis in the Democratic Republic of Congo. BMC Medicine, 19, Article number: 86. Paper summaries:  English, French
NTD Modelling Consortium Discussion Group on Gambiense Human African Trypanosomiasis (2020). Insights from quantitative and mathematical modelling on the proposed 2030 goal for gambiense human African trypanosomiasis (gHAT) [version 2; peer review: 2 approved]. Gates Open Res 2020, 3:1553. doi: 10.12688/gatesopenres.13070.2
Aliee, M, Rock, KS, Keeling, MJ (2020). Estimating the time to extinction of infectious diseases in mean-field approaches. Journal of The Royal Society Interface, 17 (173) doi: 10.1098/rsif.2020.0540 Paper summaries:  English, French
Huang, C, Crump, RE, Brown, P, Spencer, SEF,

Miaka, EM, Shampa, C, Keeling, MJ, Rock, KS (2020). Shrinking the gHAT map: identifying target regions for enhanced control of gambiense human African trypanosomiasis in the Democratic Republic of Congo. MedRxiv [pre-print, not peer-reviewed]. doi: 10.1101/2020.07.03.20145847. Paper summaries: English, French

Crump, RE, Huang, C, Knock, ES, Spencer, SEF, Brown, PE, Mwamba Miaka,E, Shampa, C, Keeling, MJ, Rock, KS (2021). Quantifying epidemiological drivers of gambiense human African Trypanosomiasis across the Democratic Republic of Congo. PLoS Computational Biology doi:10.1371/journal.pcbi.1008532 Paper summaries:  English, French

Geerts, M, Van Reet, N, Leyten, S, Berghmans, R, Rock, KS, Coetzer, THT, Eyssen, LE-A, Büscher, P (2020). Trypanosoma brucei gambiense-iELISA: A promising new test for the post-elimination monitoring of human African trypanosomiasis. Clinical Infectious Diseases, ciaa1264.

Davis, CN, Rock, KS, Keeling, MJ (2020). Human African trypanosomiasis: current status and eradication efforts. CAB Reviews. doi: 10.1079/PAVSNNR202015028

Castaño, MS, Ndeffo-Mbah, ML, Rock, KS, Palmer, C, Knock, E, Miaka, EM, Ndung’u, JM, Torr, S, Verlé, P, Spencer, SEF, Galvani, A, Bever, C, Keeling, MJ, Chitnis, N (2020). Assessing the impact of aggregating disease stage data in model predictions of human African trypanosomiasis transmission and control activities in Bandundu province (DRC). PLoS neglected tropical diseases, 14(1), e0007976. doi: 10.1371/journal.pntd.0007976

Castaño, MS, Aliee, M, Miaka, EM, Keeling, MJ, Chitnis, N, Rock, KS (2019). Screening Strategies for a Sustainable Endpoint for Gambiense Sleeping Sickness. The Journal of Infectious Diseases. doi:10.1092/infdis/jiz588

Davis, CN, Rock, KS, Miaka, EM, Keeling, MJ (2019). Village-scale persistence and elimination of gambiense human African trypanosomiasis. PLoS neglected tropical diseases, 13(10), e0007838. doi:10.1371/journal.pntd.0007838

Rock KS, Ndeffo-Mbah ML, Castaño S, Palmer C, Pandey A, Atkins KE, Ndung’u JM, Hollingsworth TD, Galvani A, Bever C, Chitnis N. (2018). Assessing strategies against Gambiense sleeping sickness through mathematical modeling. Clinical infectious diseases 66(suppl_4):S286-92. doi: 10.1093/cid/ciy018

Büscher, P, Bart, J. M., Boelaert, M, Bucheton, B, Cecchi, G, Chitnis, N, ... Rock KS et al. (2018). Do cryptic reservoirs threaten gambiense-sleeping sickness elimination?. Trends in parasitology. doi: 10.1016/j.pt.2017.11.008

Mahamat, MH, Peka, M, Rayaisse, JB, Rock, KS, Toko, MA, Darnas, J, ... & Courtin, F (2017). Adding tsetse control to medical activities contributes to decreasing transmission of sleeping sickness in the Mandoul focus (Chad). PLoS neglected tropical diseases, 11(7), e0005792. doi: 10.1371/journal.pntd.0005792

Rock, KS, Pandey, A, Ndeffo-Mbah, ML, Atkins, KE, Lumbala, C, Galvani, A, & Keeling, MJ (2017). Data-driven models to predict the elimination of sleeping sickness in former Equateur province of DRC. Epidemics, 18, 101-112. doi: 10.1016/j.epidem.2017.01.006

Rock, KS, Torr, SJ, Lumbala, C, & Keeling, MJ (2017). Predicting the impact of intervention strategies for sleeping sickness in two high-endemicity health zones of the Democratic Republic of Congo. PLoS neglected tropical diseases, 11(1), e0005162. doi: 10.1371/journal.pntd.0005162

Hollingsworth, TD, Adams, ER, Anderson, RM, Atkins, K, Bartsch, S, Basáñez, MG, ... Keeling MJ, ... Rock KS, et al. (2015). Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases. Parasites & vectors, 8(1), 630. doi: 10.1186/s13071-015-1235-1

Rock, KS Torr, SJ, Lumbala, C, & Keeling, MJ (2015). Quantitative evaluation of the strategy to eliminate human African trypanosomiasis in the Democratic Republic of Congo. Parasites & vectors, 8(1), 532. doi: 10.1186/s13071-015-1131-8

Rock, KS, Stone, CM, Hastings, IM, Keeling, MJ, Torr, SJ, & Chitnis, N (2015). Mathematical models of human African trypanosomiasis epidemiology. In Advances in parasitology (Vol. 87, pp. 53-133). Academic Press. doi: 10.1016/bs.apar.2014.12.003

Warwick researchers

HAT MEPP lead:

Kat Rock

(Associate Professor, Warwick)

Kat Rock headshot

Matt Keeling

(Professor, Warwick)

Matt Keeling headshot

Jason Madan

(Professor, Warwick)

Jason Madan headshot

Fabrizio Tediosi

(Group leader, Swiss TPH)

Fabrizio Tediosi headshot

Simon Spencer

(Associate Professor, Warwick)

Simon Spencer headshot

Louise Dyson

(Associate Professor, Warwick)

Louise Dyson headshot

Emily Crowley

(Scientific Project Manager)

Marina Antillon 

(PDRA, Swiss TPH)

Marina Antillon headshot

Ron Crump

(PDRA, Warwick)

Ron Crump headshot

Ching-I Huang

(PDRA, Warwick)

Ching-I Huang headshot

Maryam Aliee

(PDRA, Warwick)

Maryam Aliee headshot

Paul Brown

(Software Developer, Warwick)

Paul Brown headshot

Ben Millar

(PhD student, Warwick)

Ben Millar headshot

Emma Southall

(PhD student, Warwick)

Associated modellers

Nakul Chitnis

(Group leader, Swiss TPH)

Nakul Chitnis headshot

Soledad Castaño 

(PDRA, Swiss TPH)

Soledad Castaño headshot

Deirdre Hollingsworth

(Professor, Oxford)

Deirdre Hollingsworth headshot

Former team members

Xia Wang-Steverding

(PDRA, Warwick)

Xia Wang-Steverding headshot

Chris Davis

(PDRA, Warwick)

Chris Davis headshot