Development and application of Electron Diffraction (ED) techniques for determination of molecular structure.
ED is a powerful technique determining molecular structure, but it has not yet been widely adopted. The technique has undergone a revolution since the turn of the 21st centaury making it more accessible and sought-after.
The ability to select nanometer-sized regions that are free of defects, with perfect crystallinity, is a distinct advantage for ED. This should lead to improved determination of even subtle structural distortions, as seen in ferroelectric and related materials. A range of functional ceramics will be studied using MicroED and results compared to synchrotron X-ray and neutron diffraction data.
MicroED has recently been successfully applied in the field of protein structure, where cryo-electron microscopy and protein crystallography approaches can be combined to solve previously unreachable protein structures.
I'm currently working on inorganic crystals in developing a robust processing pipeline and looking to investigate and improve the dynamical scattering models in order to optimise and strengthen ED results.
Bellow is a selection of the data I have obtained:
SAED of Silicon Over 140°
SAED of Ti0.6Ca2Mn0.4O4 over 120°
SAED of Gallium Arsenide over 60°
Modelling fine-sliced three dimensional electron diffraction data with dynamical Bloch-wave simulations. (2023)
|PhD, University of Warwick||2020 - 2023|
|MSc in Analytical Science (Distinction), University of Warwick||2019 - 2020|
|BSc in Chemistry (First-class hons), University of South Wales||2011 - 2015|
Royal Society of Chemistry South East Wales Local Selection Prize 2015 – Best Final Year BSc Chemistry Project
Commended for WATE award (Warwick Award for Teaching Excellence) 2023 'Postgraduates who teach'
Royal Society Chemistry (MRSC)
Institute of Physics (MIOP)
IUCr Sig 4 (Electron Diffraction)
2017-2018 LGC Labs - Analytical scientist (Steroids, Drugs of Abuse (DOA) & Novel psychoactive Substances (NPS))
2018-2019 Malvern Panalytical - Applications Specialist - SEC/GPC