Wenjing He
MSc Project
Linear dichroism
A new method for the measurement of LD data from membranes supported on quartz was recently developed in Nikola, Chmel(Department of Chemistry) Group. The method uses a positionable turntable which allows for rotation of the quartz substrate in order to determine the three-dimensional orientation of lipid probes and peptides/proteins within lipid membranes supported on the substrate. Preliminary data show that it is possible to obtain good quality data from those systems. I am focusing on trying to improve the method to realize a better signal and its application of measuring the orientation of the protein.
Academic Background
| Qualification | organization |
Year |
| Msc in analytical science and instrumentation | University of Warwick | 2020 - 2021 |
| Bsc in Chemistry | Nanjing Normal University |
2015 - 2019 |
Previous Research
SinoUnison Technology Co., Ltd. Nanjing, China
Intern (Jul 2019 - 2020)
- Performed various chemistry tests to determine pesticide properties and optimized the procedures to remove interferences in samples to ensure a high level of accuracy.
- Prepared test reports to customers and documented measurement-based experiments relating to raw honey for traceability.
- Assisted in experimental design for analysis of volatile compounds in drinking water via GC-MS.
Enhancing the Plasmon Resonance Absorption
Key Member (Jun 2018 - Mar 2019)
- Synthesized a series of M-AuNPs and recorded images via transmission electron microscope (TEM) and high-resolution transmission electron microscope (HRTEM).
- Performed the 3D simulations via Lumerical FDTD solutions and matched the conditions with the layer absorbing boundaries.
Fluorescence Activation Imaging
Key Member (Sep 2017 - Jul 2018)
- Designed and evaluated a series of activatable DNA probes for miR-150 and disclosed the intracellular localization and distribution in HeLa cells.
- Analyzed pH-associated binding features of different probes in the mitochondria and performed MTT assays to survey the nuclease stability and cellular uptake of these probes.
Nanjing Polytechnic Institute, Nanjing, China
Intern (Jul 2018 - Sep 2018)
- Formulated steps for synthesizing alkyl sulfates and alkyl ether sulfates and helped with the characterization of other anionic surfactants.
Provided technical assistance for methanol preparation processes and batch blending processes of liquid and gel cleaning products.
Publications
- Chuanli Wu, Xiaoyan Liu, Yiyi Zhang, Wenjing He, Guancao Yang, Ping Wu and Chenxin Cai, Fluorescence Activation Imaging of Localization, Distribution, and Level of miRNA in Various Organelles inside Cells, Talanta, Vol 186, 406-412, 2018.
- Yaojuan Hu, Xiaoyan Liu, Zhewei Cai, Hui Zhang, Han Gao, Wenjing He, Ping Wu, Chenxin Cai, Junjie Zhu and Zijie Yan, Enhancing the Plasmon Resonance Absorption of Multibranched Gold Nanoparticles in the Near-Infrared Region for Photothermal Cancer Therapy: Theoretical Predictions and Experimental Verification, Mater., 31, 2, 471-482, 2019.
Contact me
Email: Hewenjing7@outlook.com
University of Warwick
CV4 7AL