Yi Ting Loo
Hello!
I am a 2nd year PhD student at MathSys II CDT,Link opens in a new window under the supervision of Prof Timothy Saunders (Warwick)Link opens in a new window, and part of the Saunders LabLink opens in a new window at the Centre for Mechanochemical Cell Biology (CMCB)Link opens in a new window. My main research interests are mathematical biology and biophysical modelling. For my PhD project, I study pattern formation and cell fate acquisition during organ development, and how complex tissue shapes emerge. I study the dynamics of organ morphogenesis through modelling with PDEs or other computational methods, of a specific organoid (stem cell culture) development, cultured in a spatially constrained environment. In my research, I also work on image analysis of immunofluorescence microscopy images to obtain data for modelling. This project is part of a wider collaboration with the Briscoe LabLink opens in a new window (Crick InstituteLink opens in a new window). As part of my PhD, I am also working on the movement and diffusion of molecules in a tortuous extracellular environment. This work is in collaboration with the Biophysical Fluorescence LaboratoryLink opens in a new window at NUS, Singapore led by Prof Thorsten WohlandLink opens in a new window.
Education
University of Warwick, Coventry, UK
- MSc Mathematics of Systems (with Distinction) (Autumn 2021 - Summer 2022)
- BSc (Hons) Mathematics and Physics (First Class Honours) (Autumn 2018 - Summer 2021)
Publications
Zhu S, Loo YT, Veerapathiran S, Loo TYJ, Tran BN, Teh C, Zhong J, Matsudaira P, Saunders TE, Wohland T. Receptor binding and tortuosity explain morphogen local-to-global diffusion coefficient transition. Biophys J. 2024 Jul 24:S0006-3495(24)00483-1. [BiophysicalLink opens in a new window][GitHubLink opens in a new window]
Conferences
- Poster Presentation at the European Molecular Biology Laboratory (EMBL) Symposium, (The Mechanics of Life: From development to diseaseLink opens in a new window) at Heidelberg, Germany (April 2024).
- Contributed Talk at the Warwick-Cambridge Quantitative Cell Biology SymposiumLink opens in a new window, Coventry, UK (May 2024).
Teaching 23/24
- Teaching assistant for fourth-year undergraduate module MA4M9 Mathematics of Neuronal NetworksLink opens in a new window.
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Teaching assistant for second-year undergraduate module MA256 Introduction to Mathematical BiologyLink opens in a new window.
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Marking assistant for first-year undergraduate module MA147 Mathematical Methods and Modelling 1Link opens in a new window.
Teaching 22/23
Small group supervisions for first-year BSc MathStats students, modules include:
| Term 1 MA140 Mathematical Analysis 1 MA138 Sets and Numbers |
Other Activities:
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Committee member (Communications Officer) of the Warwick SIAM-IMA Student ChapterLink opens in a new window (2023/24 and 2024/25). I manage events publicity and handle all chapter activities websites:
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Statistics, Probability, Analysis and Applied Mathematics (SPAAM) seminar seriesLink opens in a new window (weekly seminars during term)
- Applied Mathematics Postgraduate (AMP) ConferenceLink opens in a new window (8-10 July 2024) (postgraduate research conference and workshop on Communicating Research)
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Previous Research Projects
- Quantitative modelling of tissue morphogenesis using vertex models
(MSc Individual project, summer 2022)
Supervised by Prof Timothy Saunders, working in the Saunders Lab; with external collaborator Dr James Briscoe from The Francis Crick Institute. - Cyclists' cardiac conundrum:
Characterising features of athletes' heart rate data and finding the correlation with arrhythmia
(MSc Group project, spring 2022)
Supervised by Prof Colm Connaughton; and external partner Ian Green from Crickles; with group members Andrew Nugent and Jack Buckingham. - From stochastic model of single neurons to neuronal population
(BSc Final year project, autumn 2020 - spring 2021)
Supervised by Prof Magnus Richardson. - Modelling the impact of vaccination on the spread of multi-strain dengue virus in South East Asia
(URSS Project, summer 2020)
Supervised by Prof Michael Tildesley and Dr Warren Tenant.
Previous Work Experiences:
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Postgraduate student project partner for WIHEA's project: Creating a 'Support the Supporter' resourceLink opens in a new window for Undergraduate Student Research (Spring 2022)
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Research assistant at Global Nano NetworkLink opens in a new window (Summer 2021)
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Student director of International Conference of Undergraduate Research (ICUR)Link opens in a new window 2021 (Autumn 2020-Autumn 2021)
Contact
Email:
Offices:
D2.11, Zeeman Building
Level 3, IBRB, Gibbet Hill Campus
Skills
Programming Languages:
- Proficient in Python (primary programming language), working knowledge of Julia and MATLAB.
Image Analysis Tools:
- Fiji ImageJ, Paraview.
Others:
- LaTeX, GitHub
- Finite element solver for PDEs: FEniCS on Python.