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Research Theme 1: Long-Term Conditions

Integrated and holistic care

The care of people with long-term conditions currently accounts for 70% of healthcare expenditure. Feedback from patients suggests the care system has a long way to go in providing patient-focussed, seamless care, integrated across organisational boundaries.

In this, our largest theme, we will work with local organisations and patients to improve the management of long-term conditions and evaluate new models of care designed to improve integration, patient satisfaction and efficiency.

Theme lead

Professor Christian Mallen
Keele University



  • We will undertake studies that are an immediate local priority, that can plausibly generate evaluations of widespread roll-out, and that explicate theory.
  • We will co-design and pilot new evidence-based interventions, which can be tested in multiple sites through NIHR-funded research.


  • Our results will be used to influence policy at home and abroad in areas of massive interest to services, patients and citizens.

Latest updates

Bringing innovative research methods to clustering analysis of multimorbidity

Lead: Tom Marshall

Dates: 01/10/2019 - 31/03/2022

Funding Body: MRC

CAse-fInding foR depressiOn in primary care

Lead: Christian Mallen

Dates: 01/08/2019 - 31/01/2021

Funding: NIHR Professorship

Evaluation of MyHealth patient platform for transplant patients

Lead: Elaine O'Connell Francischetto

Dates: 03/01/2016 -

Funding: NIHR ARC West Midlands