Events

Abstract: Optical imaging is widely used in biomedical sciences. Despite the wide range of optical imaging techniques available, there is no one universal modality suitable for all length scales and types of biological samples. Confocal and light sheet microscopes are two popular optical imaging modalities that are routinely used for imaging live and fixed samples at multiple spatial and temporal scales. I will discuss our group’s efforts to advance these technologies for imaging large or rapidly growing samples at high spatial and temporal resolutions. Specifically, I will present our implementation of a confocal microscope for improving imaging speed by a few orders of magnitude for large samples. I will then show the use of this imaging technique, in collaboration with your colleagues, to answer important biological questions in systems ranging from living zebrafish embryos to whole cleared mammalian organs.