Poster Gallery
The Poster Gallery below is a small selection of the 216 posters exhibited in the WorldCUR-BCUR 2023 Poster Exhibition.
All delegates were given the opportunity to take part in the below display, if you were a WorldCUR-BCUR 2023 Poster Exhibition presenter and would like your poster included in this gallery, please contact worldcur@warwick.ac.uk.
 
 
      Raviya Careem, State University of New York at Oswego
 
 
      Understanding the structural basis of small molecule inhibitors of Mycobacterium tuberculosis DosS
Other authors: Eaindra Yee, Murphi Williams and Dr. Ambika Bhagi-Damodaran
 
 
      Napat Uraisomsurat, Institute of Field Robotics
The Study of Difficulties in Handling Plastic Waste for Achieving Sustainable Plastic Waste Management
Other authors: Thanaphan Rueangsuk, Khatatip Osirikan, Thayida Thiamthad
 
 
       
 
      Estefanía Fonseca Bayona, Universidad EAFIT
Design of a Tool for the Identification and Self-Repair of Low-Cost Exomodular Transtibial Prostheses for Amputees in the Colombian Agricultural Sector.
Other authors: Valentina Jaramillo Tobón, Mateo Angel Palacio, Santiago Moná Echavarría, Yuliana Olaya Bedoya
Isabeau Burnett, University of Chicago
Examining Racial, Ethnic, and Sex Differences as Predictors of Cannabis Use Disorder Treatment Retention.
Other authors: Nathaniel L. Baker, Rachel L. Tomko, Aimee L. McRae-Clark, Kevin M., Gray MD & Erin A. McClure
 
 
      Yancey Williams, University of Alabama at Birmingham
 
 
      Computational Modeling of Endocytic Vesicle Formation Image
Other authors: Tomasz J. Nawara, Jie Yuan, Tejeshwar C.Rao, Elizabeth Sztul and Alexa L. Mattheyses
 
 
       
 
       
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
       ![Every four seconds a new patient is diagnosed with Alzheimer’s Disease (AD) with 7.7 million new cases reported annually worldwide. AD is a progressive neurodegenerative form of dementia characterised by cognition decline. The leading cause of AD is the build-up of amyloid and tau proteins among brain cells, which prevents intercellular communication and inevitably influences memory loss.   Alarmingly, cases are predicted to increase up to 145 million by 2050 worldwide. As a growing epidemic, AD imposes a financial burden globally with annual costs above £818 billion. Scientists have tried to find a cure since its discovery in 1906. Treatments either target amyloid proteins or temporarily slow AD progression.  AD is manifested by abnormally low levels of acetylcholine (ACh), a neurotransmitter used for intercellular communication. Acetylcholinesterase (AChE) is an enzyme that breaks down ACh; thus, inhibiting its activity can prevent ACh reduction.  Our project aimed to synthesise new pyrrolo[1,2-a]quinoxaline analogues as potential AChE inhibitors. This project presents a novel approach using thiols as an alternative to tin, which is toxic and, based on the literature, is the most preferred method. The compounds were assayed, with some showing low toxicity and excellent selectivity towards AChE.   According to recent studies, sulfaquinoxaline, which is toxic, can eliminate amyloid proteins immensely. Therefore, less toxic analogues are alternatively suggested, including the pyrrolo[1,2-a]quinoxalines series we designed, which share a common scaffold with sulfaquinoxaline. Consequently, further steps involve testing our compounds to determine if they can reduce amyloid plaque accumulation.](margarita_damai_worldcur_2023_poster_page-0001.jpg) 
 
        
 
        
 
       
 
       
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
        
 
       