e-Participate
OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE)
Background
Evidence suggests that large reductions in blood pressure, and too many drug prescriptions may be associated with an increase in serious falls and death in the elderly.
Assessing the safety of reducing medication in older patients (≥80 years) with controlled systolic blood pressure (<150 mmHg), who are receiving ≥2 antihypertensive medications. Systolic blood pressure control at three month follow-up will be compared between those randomly allocated to either removal of one blood pressure medication or usual care.
Participants will have the following visits
1. Consent visit and baseline visit for all participants
2. four week safety visit for those randomised to medication reduction
3. 12 week follow up for all participants
‘It has been one of the more well supported studies that I have been involved with and certainly one of the more interesting.’
A quote from one GP involved in the study
Recruitment
Currently recruiting practices and looking to complete participant recruitment by August 2018.
*Due to the short follow up and strong support from the CRN and trial team for this study, it would be a great first CTIMP trial for any GP looking to get more involved in research! *
For more information, please contact your local facilitator, details on page 12 of Participate Spring 2018