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Professor Joanna Collingwood - Publications




  • James Everett, Frederik Lermyte, Jake Brooks, Vindy Tjendana-Tjhin, Germán Plascencia-Villa, Ian Hands-Portman, Jane M. Donnelly, Kharmen Billimoria, George Perry, Xiongwei Zhu, Peter J. Sadler, Peter B. O’Connor, Joanna F. Collingwood, Neil D. Telling, Biogenic metallic elements in the human brain? SCIENCE ADVANCES 09 JUN 2021 : EABF6707 Vol. 7, no. 24, eabf6707 DOI: 10.1126/sciadv.abf6707


  • Brooks J, Everett J, Lermyte F, Tjendana Tjhin V, Sadler PJ, Telling N, ... Collingwood JF. (2020). Analysis of neuronal iron deposits in Parkinson's disease brain tissue by synchrotron x-ray spectromicroscopy. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 62, pp. 126555. doi: 10.1016/j.jtemb.2020.126555
  • Brooks, Jake, Everett, James, Lermyte, Frederik, Tjhin, Vindy Tjendana, Sadler, P. J., Telling, Neil D. and Collingwood, Joanna F. (2020) Data for Analysis of neuronal iron deposits in Parkinson's disease brain tissue by synchrotron x-ray spectromicroscopy. [Dataset]
  • Everett J, Brooks J, Lermyte F, O'Connor PB, Sadler PJ, Dobson J, ... Telling ND. (2020). Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ(1-42). Scientific reports, 10(1), pp. 10332. doi: 10.1038/s41598-020-67117-z
  • Surya Rajan, Julia Brettschneider and Joanna Collingwood, Regional segmentation strategy for DTI analysis of human corpus callosum indicates motor function deficit in mild cognitive impairment, Journal of Neuroscience Methods, 2020, DOI: 10.1016/j.jneumeth.2020.108870
  • Brooks J, Everett J, Lermyte F, Tjhin VT, Banerjee S, O'Connor PB, ... Collingwood JF. (2020). Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. Angewandte Chemie (International ed. in English), 59(29), pp. 11984-11991. doi: 10.1002/anie.202000239
  • Aliakbari F, Mohammad‐Beigi H, Abbasi S, Rezaei‐Ghaleh N, Lermyte F, Parsafar S, ... Otzen D. (2020). Multiple Protective Roles of Nanoliposome‐Incorporated Baicalein against Alpha‐Synuclein Aggregates. Advanced Functional Materials, (7), doi: 10.1002/adfm.202007765
  • Lermyte F, Zhang WY, Brooks J, Huband S, Collingwood JF, Lees MR, ... Sadler PJ. (2020). Metallic iron in cornflakes. Food & function, 11(4), pp. 2938-2942. doi: 10.1039/C9FO02370D
  • Marvian AT, Aliakbari F, Mohammad-Beigi H, Ahmadi ZA, Mehrpooyan S, Lermyte F, ... Morshedi D. (2020). The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization. International journal of biological macromolecules, 155, pp. 543-550. doi: 10.1016/j.ijbiomac.2020.03.238 


  • Frederik Lermyte et. al., Metal Ion Binding to the Amyloid β Monomer Studied by Native Top-Down FTICR Mass Spectrometry, Journal of the American Society for Mass Spectrometry, 2019, DOI: 10.1007/s13361-019-02283-7

  • Frederik Lermyte, James Everett et. al., Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies, Cells, 2019, 8(10):1231 DOI: 10.3390/cells8101231
  • Anne-Claire Jacomin et. al., Impact of autophagy and aging on iron load and ferritin in Drosophila brain, Frontiers in Cell and Developmental Biology, 2019 DOI: 10.3389/fcell.2019.00142
  • Adam P. Hitchcock, Xiaoyue Wang, Kathryn Grandfield, James Everett, Joanna F. Collingwood, Neil D. Telling: Correlative Spectromicroscopy and Tomography for Biomedical Applications Involving Electron, Ion, and Soft X-ray Microscopies. Microscopy Today 03/2019; 27(02):12-19., DOI:10.1017/S1551929518001256
  • Mary E. Finnegan, Naomi Visanji, Isolda Romero-Canelon, Emily House, Surya Rajan, J. Frederick W. Mosselmans, Lili-Naz Hazrati, Jon Dobson, Joanna F. Collingwood: Synchrotron XRF imaging of Alzheimer’s disease basal ganglia reveals linear dependence of high-field magnetic resonance microscopy on tissue iron concentration. Journal of Neuroscience Methods 03/2019;, DOI: 10.1016/j.jneumeth.2019.03.002
  • Goenaga Infante, Heidi, Warren, John, Chalmers, John, Dent, Geoffrey, Todoli, Jose Luis, Collingwood, Joanna, Telling, Neil, Resano, Martin, Limbeck, Andreas, Schoenberger, Torsten, Hibbert, D. Brynn, LeGresley, Adam, Adams, Kristie and Craston, Derek. "Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)" Pure and Applied Chemistry, pp. 000010151520190203.


  • J. Everett, J.F Collingwood, V. Tjendana-Tjhin, J. Brooks, F. Lermyte, G. Plascencia-Villa, I. Hands-Portman, J. Dobson, G. Perry, N. D Telling, “Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects”, Nanoscale, 2018, v.10, 11782-11796 DOI: 10.1039/C7NR06794A
  • J. Everett et. al., Nanoscale Examination of Biological Tissues Using X-ray Spectromicroscopy, Microscopy and Microanalysis, 2018, 24(S2):490-491 DOI: 10.1017/S143192761801468X
  • T. Al-sandaqchi, C. Brignell, J.F. Collingwood, K. Geraki, E.M. Mirkes, K. Kong, M. Castellanos, S.T. May, C.W. Stevenson and H.M. Elsheikha, “Metallome of cerebrovascular endothelial cells infected with Toxoplasma gondii using μ-XRF imaging and inductively coupled plasma mass spectrometry”, Metallomics, 2018, 10, 1401-1414 DOI: 10.1039/C8MT00136G
  • Aliakbari, H. Mohammad-Beigi, N. Rezaei-Ghaleh, S. Becker, F. Dehghani Esmatabad, H. Alsadat Eslampanah Seyedi, H. Bardania, A. Tayaranian Marvian, J.F. Collingwood, G. Christiansen, M. Zweckstetter, D.E. Otzen and D. Morshedi “The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's DiseaseNanoscale, 2018, v10, 9174-9185


  • Neil D. Telling, James Everett, Joanna F. Collingwood, Jon Dobson, Gerrit van der Laan, Joseph J. Gallagher, Jian Wang, Adam P. Hitchcock: Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease. Cell Chemical Biology 09/2017; DOI:10.1016/j.chembiol.2017.07.014
  • Joanna F Collingwood, Freddy Adams: Chemical imaging analysis of the brain with X-ray methods. Spectrochimica Acta Part B Atomic Spectroscopy 02/2017; 130. DOI:10.1016/j.sab.2017.02.013
  • Joanna F. Collingwood, Freddy Adams: X-Ray Microscopy for Detection of Metals in the Brain. Metals in the Brain, 01/2017; DOI:10.1007/978-1-4939-6918-0_2


  • Vindy Tjendana Tjhin, Simon Mitchell, Michael Chappell, Elizabeth A. Milward, and Joanna F. Collingwood (2016) 'A computational model of iron transport between the blood circulation and the brain', Abstract from the Twentieth International Congress of Parkinson's Disease and Movement Disorders, Movement Disorders Volume: 31 S2 Abstract number 1851, page S608-609, DOI 10.1002/mds.26688

  • Moones Heidari, Sam H. Gerami, Brianna Bassett, Ross M. Graham, Anita C.G. Chua, Ritambhara Aryal, Michael J. House, Joanna F. Collingwood, Conceição Bettencourt, Henry Houlden, Mina Ryten, for the UK Brain Expression Consortium (UKBEC), John K. Olynyk, Debbie Trinder, Daniel M. Johnstone, Elizabeth A. Milward. (2016) 'Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases' Rare Diseases Vol. 4, Iss. 1 DOI: 10.1080/21675511.2016.1198458

  • Collingwood, J.F., and Telling, N.D., 'Iron Oxides in the Human Brain', Chapter · June 2016 In book: Iron Oxides: From Nature to Materials and from Formation to Applications, Edition: First, Publisher: Wiley-VCH, Editors: Damien Faivre, DOI: 10.1002/9783527691395.ch7

  • Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jiménez MJ, Zhu X, Rogers JT, Betancourt I, José-Yacamán M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Scientific Reports Sci Rep. 2016 Apr 28;6:24873. DOI:10.1038/srep24873
  • M Heidari, D M Johnstone, B Bassett, R M Graham, A C G Chua, M J House, J F Collingwood, C Bettencourt, H Houlden, M Ryten, J K Olynyk, D Trinder and E A Milward for the UK Brain Expression Consortium (UKBEC) (2016) 'Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features'. Molecular Psychiatry, DOI: 10.1038/mp.2015.192


  • Bettencourt C, Forabosco P, Wiethoff S, Heidari M, Johnstone DM, Botía JA, Collingwood JF, Hardy J, Milward EA, Ryten M, Houlden H; UK Brain Expression Consortium (UKBEC), (2015) 'Gene co-expression networks shed light into diseases of brain iron accumulation', Neurobiol Dis. S0969-9961(15)30106-6. doi: 10.1016/j.nbd.2015.12.004
  • Collingwood, J.F., "Iron in the blood and the brain", Letter to New Scientist 226(3027):54-54 · June 2015


  • Collingwood, J.F. and Davidson, M.R. (2014) 'The role of iron in neurodegenerative disorders: insights and opportunities with synchrotron light'. Frontiers in Pharmacology, 5, 191, DOI: 10.3389/fphar.2014.00191.

  • Everett, J., Cespedes, E., Shelford, L. R., Exley, C., Collingwood, J. F. , Dobson, J., van der Laan, G., Jenkins, C. A., Arenholz, E. ,Telling, N. D. (2014) 'Evidence of Redox-Active Iron Formation Following Aggregation of Ferrihydrite and the Alzheimer's Disease Peptide beta-Amyloid'. Inorganic Chemistry, DOI: 10.1021/ic402406g
  • J. Everett, E. Céspedes, L.R. Shelford, C. Exley, J.F. Collingwood, J. Dobson, G. van der Laan, C.A. Jenkins, E. Arenholz and N.D. Telling (2014) 'Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimerʼs disease peptide β-amyloid (1-42)', Journal of the Royal Society Interface, 11(95):20140165. doi: 10.1098/rsif.2014.0165


  • Visanji NP, Collingwood JF, Finnegan ME, Tandon A, House E, Hazrati LN. (2013) 'Iron Deficiency in Parkinsonism: Region-Specific Iron Dysregulation in Parkinson's Disease and Multiple System Atrophy'. J Parkinsons Dis. PMID: 24113558
  • F. Skidmore, M. Yang, L. Baxter, K. von Deneen, J. Collingwood, G. He, D. Korenkevych, A. Savenkov, K. White, K. Heilman, M. Gold, Y. Liu (2013) 'Reliability Analysis of the Resting State Can Sensitively and Specifically Identify the Presence of Parkinson Disease', Neuroimage, PMID:2192436
  • F. Skidmore, M. Yang, L. Baxter, K. von Deneen, J. Collingwood, G. He, R. Tandon, D. Korenkevych, A. Savenkov, K. Heilman, M. Gold, Y. Liu (2013) 'Apathy, Depression, and Motor Symptoms Have Distinct and Separable Resting Activity Patterns in Idiopathic Parkinson Disease', Neuroimage, PMID:21782030


  • Gallagher JJ, Finnegan ME, Grehan B, Dobson J, Collingwood JF, Lynch MA (2012) 'Modest amyloid deposition is associated with iron dysregulation, microglial activation, and oxidative stress', J Alzheimers Dis. 28(1):147-61. PMID:21971404
  • Ugarte M., Grime G.W., Lord G., Geraki K., Collingwood J.F., Finnegan M.E., Farnfield H., Merchant M., Bailey M., Ward N.I., Foster P., Bishop P.N. and Osborne N.N.. (2012) 'Concentration of various trace elements in the rat retina and their distribution in different structures', Metallomics, 4(12):1245-54, DOI:10.1039/C2MT20157G. PMID:23093062

  • Antharam V, Collingwood JF, Bullivant JP, Davidson MR, Chandra S, Mikhaylova A, Finnegan ME, Batich C, Forder JR, Dobson J (2012) 'High field magnetic resonance microscopy of the human hippocampus in Alzheimer's disease: quantitative imaging and correlation with iron', Neuroimage, 59(2):1249-60, PMID:21867761


  • M.R. Davidson, S. Stoupin, D. DeVito, J. Collingwood, C. Segre, and P.H. Holloway, (2011) Local compositional environment of Er in ZnS:ErF3 thin film electroluminescent phosphors, J. Appl. Phys. 109, 054505 (2011);
  • C. Exley, E. House, J.F. Collingwood, M.R. Davidson, D. Cannon, A.M. Donald (2010) 'Spherulites of Aß42 in vitro and in Alzheimer's disease' Journal of Alzheimer's Disease 20 (4), p 1159 - 1165 (1387-2877) [article]Link opens in a new window
  • E. House, M. Mold, J. Collingwood, A. Baldwin, S. Goodwin and C. Exley (2009) 'Copper abolishes the ß-sheet secondary structure of preformed amyloid fibrils of Aß42' Journal of Alzheimer's Disease 18 (4), p 811 - 817 (1387-2877)
  • J. F. Collingwood, S. B. Palmer, M. R. Lees, C. Edwards, J. A. Santos, J. B. Sousa and D. C. Jiles (2009) 'Ferro I phase and gadolinium' Physical Review B-Condensed Matter 79, p 104401 (1098-0121)
  • J.F. Collingwood , S. Chandra, M. Davidson, A. Mikhaylova, T. Eskin, J. Dobson, J. Forder, C. Batich (2008) 'High-resolution Magnetic Resonance Imaging To Quantify Relaxation Parameters In Alzheimer's Brain Tissue', Alzheimer's and Dementia, 4 (4), S2
  • J.F. Collingwood, R.K. Chong, T. Kasama, L. Cervera-Gontard, R.E. Dunin-Borkowski, G. Perry, M. Posfai, S.L. Siedlak, E.T. Simpson, M.A. Smith and J. Dobson (2008) 'Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material' Journal of Alzheimer's Disease 14 (2), p 235 - 245 (1387-2877)
  • R.E. Dunin-Borkowski, T. Kasama, M. Posfai, R.K.K. Chong, E.T. Simpson, J. Dobson and J.F. Collingwood (2008) 'Off-axis electron holography of magnetic fields in biological materials', Microscopy and Microanalysis, 14 (S2), p 54 - 55 (1431-9276)
  • A. E. Oakley, J. F. Collingwood, J. Dobson, G. Love, H. R. Perrott, J. A. Edwardson, M. Elstner and C. M. Morris (2007) 'Individual dopaminergic neurons show raised iron levels in Parkinson disease', Neurology, 68, p 1820 - 1825 (0028-3878)
  • J. Dobson and J.F. Collingwood (2007) 'Response to comment on 'Mapping and characterization of iron compounds in Alzheimer's tissue', Journal of Alzheimer's Disease, 11, p 469 - 470 (1387-2877)
  • J.F. Collingwood and J. Dobson (2006) 'Mapping and characterization of iron compounds in Alzheimer's disease', Journal of Alzheimer's Disease, 10, p 215 - 222 (1387-2877)
  • Y. Gossuin, D. Hautot, R. Muller, Q. Pankhurst, J. Dobson, C. Morris, P. Gillis, J. Collingwood (2005) 'Looking for biogenic magnetite in brain ferritin using NMR relaxometry', NMR in Biomedicine, 18, p 469 - 472 (0952-3480)
  • J.F. Collingwood, A. Mikhaylova, M. Davidson, C. Batich, W.J. Streit, T. Eskin, J. Terry, and Jon Dobson (2005) 'High resolution x-ray absorption spectroscopy studies of metal compounds in neurodegenerative brain tissue', Journal of Physics: Conference Series, 17, p 54 - 60 (1742-6588)
  • J.F. Collingwood, A. Mikhaylova, M. Davidson, C. Batich, W.J. Streit, J. Terry, J. Dobson (2005) 'In-situ Characterization and Mapping of Iron Compounds in Alzheimer?s Tissue', Journal of Alzheimer's Disease, 7, p 267 - 272 (1387-2877)
  • J.A.M. Santos, J.F. Collingwood, J.B. Sousa, S.B. Palmer (2004) 'Anomalous magnetoresistance near the spin reorientation transition of dilute Gd-Y single crystals', Journal Of Magnetism And Magnetic Materials, 272-276 e491 - e492 (0304-8853)
  • E. House, J. Collingwood, A. Khan, O. Korchazkina, G. Berthon, and C. Exley (2004) 'Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Aß42 in a manner which may have consequences for metal chelation therapy in Alzheimer?s disease', Journal of Alzheimer's Disease, 6 291 - 301 (1387-2877)
  • J.F. Collingwood, C. Edwards, S.B. Palmer, J.A.M. Santos and J.B. Sousa (2003) 'Magnetic phase behaviour for Gd-rich Gd-Y', Journal Of Applied Physics, 93, p 8349 - 8351 (0021-8979)
  • J.P. Camplin, S.M. Thompson, D.R. Loraine, D.I. Pugh, J.F. Collingwood, E.M. McCash, A.B. Horn (2000) 'Contactless measurement of giant magnetoresistance in thin films by infrared reflection', Journal Of Applied Physics, 87, p 4846 - 4848 (0021-8979)


  • 'Imaging of the transition metals in the brain', The 2nd International Conference INNOVATIVE TECHNOLOGIES IN BIOMEDICINE, Krakow, Oct 2015
  • 'Shining many lights on the dysregulation of brain iron in neurodegenerative disease', Sustainable Futures: 21st Century Technologies for Health, University of Warwick, Singapore, March 2015
  • 'Examining the relationship between brain iron and MRI', University of Nottingham, Queens Medical Centre, Oct 2014
  • Brain iron imaging in neurodegeneration, 'University Hospitals Coventry and Warwickshire, Oct 2014
  • 'Imaging transition metals in the brain: Recent observations with X-rays and MRI', AGH-University of Science and Technology, Krakow, Oct 2013
  • 'X-ray fluorescence imaging for biology', Hercules Course HSC15, ESRF, Grenoble, Sept 2013
  • 'Chasing metals in the degenerating brain: Recent observations with synchrotrons, SQuIDs, and MRI', Physical Sciences of Imaging in the Biomedical Sciences (PSIBS) Centre, University of Birmingham, Jan 2013
  • 'Synchrotrons and SQuIDS: unusual perspectives on iron and other transition metals in tissues from the human brain in AD, PD and MSA', Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, May 2011
  • 'Brain Iron Deposition', International Society for Magnetic Resonance in Medicine (ISMRM) Annual Meeting, Montreal, May 2011
  • 'XRF analysis of neurodegenerative brain tissue using synchrotron radiation', The British Crystallographic Association Spring Meeting, Keele, April 2011
  • 'Transition Metals and Neurodegenerative Disorders: Synchrotron X-ray Fluorescence Analysis Of Trace Metals' 3rd Zinc UK Meeting, University College London, Feb 2011
  • 'Metals and neurodegeneration – the hunt for elusive elements in the brain', MOAC Doctoral Training Centre, University of Warwick, Jan 2011
  • 'Disrupted iron metabolism in the degenerating brain?', ARCHA, Aston University, Dec 2010


  • Dan M. Johnstone, Moones Heidari, Brianna Bassett, Anita C.G. Chua, John K. Olynyk, Debbie Trinder, Joanna F. Collingwood, Elizabeth A. Milward, 'MAPPING THE BRAIN METALLOME OF A MOUSE MODEL OF IRON OVERLOAD', 8th International Conference on Heme Oxygenases, BioIron and Oxidative Stress (2014) Sydney, Australia

  • J.F. Collingwood, M.E. Finnegan, Z. Arya, J.-P. Hagen, S. Chen, A. Chowdhury, S. Wayte, E. Ngandwe, N. Visanji, J. Dobson, P.A. Gowland, L.-N. Hazrati, & C.E. Hutchinson, ‘MRI evaluation of the relationship between R2, R2*, and tissue iron in the human basal ganglia’, International Society for Magnetic Resonance in Medicine Annual Meeting (2014), Milan, Italy

  • M. E. Finnegan, N. Visanji, E. House, V. Antharam, J.-P. Bullivant, A. Mikhailova, M. Lees, J. Dobson, L.-N. Hazrati, J. F. Collingwood, 'Tissue iron accumulation in Alzheimer’s disease parallels increased grey/ white matter contrast in MRI of the human pons', The 11th International Conference on Alzheimer's & Parkinson's Diseases (2013) Florence, Italy
  • M. Finnegan, J.F. Collingwood,, N. Visanji, E. House, M.R. Lees, V. Antharam, A. Mikhailova, J. Dobson, L.-N. Hazrati, 'Determining the source of elevated iron concentrations in the human pons in neurodegenerative disorders', The 10th International Conference on Alzheimer's & Parkinson's Diseases (2011) Barcelona, Spain
  • N.P. Visanji, J.F. Collingwood, M. Finnegan, E. House, A. Tandon, L.-N. Hazrati, (2011) 'Disregulation of iron storage in multiple systems atrophy', The 10th International Conference on Alzheimer's & Parkinson's Diseases (2011) Barcelona, Spain
  • Naomi Visanji, Joanna Collingwood, Mary Finnegan, Emily House, Anurag Tandon and Lili-Naz Hazrati, 'Disregulation of iron storage in multiple system atrophy', Canadian Association of Neuropathologists 50th Annual Meeting (2010), Toronto, Canada
  • Mary Finnegan, Joanna Collingwood, Jon Dobson, Vijay Antharam, Albina Mikhailova, John Forder, Mark Davidson, JP Bullivant, Chris Batich, Naomi Visanji, Fred Mosselmans, and Paul Quinn, 'Can altered brain iron in Alzheimer's Disease be identified via MRI?' SINAPSE Annual Meeting (2010), Edinburgh, UK
  • Daniel Zajarias-Fainsod, Michael J Chappell, Joanna F Collingwood, Adam Rennie, Sanjoy Nagaraja, and Adrian Wilson, 'Patient-specific Modelling of Blood-flow in Cerebral Aneurysms', COMSOL Conference (2010), Boston, USA


  • J.F. Collingwood and J. Dobson (2007) 'Nanoscale iron compounds related to neurodegenerative disorders', Chapter 18 in Biomedical Nanostructures 461- 490, John Wiley