I graduated from the University of Southampton in 2013 with a Masters in Chemistry (MChem), I am now currently undertaking a PhD at the University of Southampton co-supervised by Prof Malcolm Levitt and Dr Phil Williamson
My research project is focused on cryogenic magic-angle spinning NMR techniques for biomolecular samples.
Significant enhancements in sensitivity can be obtained through the acquisition of NMR data at cryogenic temperatures with the potential to revolutionise the study of biomolecular systems. Sensitivity enhancements will greatly facilitate the analysis of biomolecular systems such as fibrillar or membrane proteins, proteins that express poorly, and of protein states that are not highly populated.
The University of Southampton has developed one of the few systems in the world capable of performing magic-angle-spinning NMR at cryogenic temperatures. The current project will develop the techniques required to take advantage of this system in the context of biomolecular applications.
Many of the methods developed will facilitate the application of technologies such as dynamic nuclear polarization at cryogenic temperature.
Conferences and Workshops02/12/2013-06/12/2013; University of Warwick; 2013 iMR CDT Kick-Off Workshop