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Alex Clarke (Associate Professor)

Alex Clarke

 

Interests:

How does the brain make sense of the world?

We can recognise tens of thousands of objects, but despite this vast number, our recognition is remarkably quick and accurate, completed within a few hundred milliseconds.

Recognition depends on a multitude of dynamic transformations of information in the brain, from low-level visual attributes through to higher-level visual representations and semantic meaning – not simply the name of the object, but access to the relevant properties of the object and how it relates to other objects. Our ability to rapidly recognise objects in our environment is fundamental to acting appropriately in the world. The rapid extraction of semantic meaning from vision provides a platform for complex behaviours such as object identification, object use and navigational planning, and without accessing semantics, we would not be able to communicate to others about our environment. My research ask what are the neural dynamics and mechanisms by which vision activates semantics.

How does the visual environment shape the process of recognition?

Recognising objects depends on dynamic transformations of information from vision to semantics - but in the real world, our understanding of what we see is shaped by the environment. When we see an object, we are already in a complex and rich environment and this leads to expectations about the things we are likely to see.

My research tests how the environment changes the dynamics of visual and semantic activity in the brain, using a multimodal brain imaging framework based on fMRI, MEG, EEG and mobile EEG, with emerging methodologies including augmented reality, computational modelling, multivariate analyses, neural oscillations and brain connectivity.

A full list of publications and further information about me can be seen on my personal website

Personal webpage: https://sites.google.com/site/alexclarkebrains/home

Contact Details

 

Representative Publications:

  • von Seth J, Nicholls VI, Tyler LK & Clarke A. (2023). Recurrent connectivity supports higher-level visual and semantic object representations in the brain. Communications Biology.

  • Krugliak A, Draschkow D, Võ MLH, & Clarke A. (2023). Semantic object processing is modulated by prior scene context. Language, Cognition and Neuroscience.

  • Clarke A, Crivelli-Decker JE, & Ranganath C. (2022). Contextual expectations shape cortical reinstatement of sensory representations. Journal of Neuroscience, 42 (30).

  • Krugliak A & Clarke A. (2022). Towards real-world neuroscience using mobile EEG and augmented reality. Scientific Reports 12, Article number: 2291.

  • Clarke, A., Devereux, B.J., & Tyler, L.K. (2018). Oscillatory dynamics of perceptual to conceptual transformations in the ventral visual pathway. Journal of Cognitive Neuroscience, 30(11), 1590-1605.

  • Clarke, A., & Tyler, L.K. (2015). Understanding What We See: How We Derive Meaning From Vision. Trends in Cognitive Sciences. 19(11): 677-687.

  • Clarke, A., Devereux, B.J., Randall, B., & Tyler, L.K. (2015). Predicting the time course of individual objects with MEG. Cerebral Cortex.

  • Clarke, A., & Tyler, L.K. (2014). Object-Specific Semantic Coding in Human Perirhinal Cortex. Journal of Neuroscience, 34(14), 4766-4775.