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Facilities

We have a range of facilities and equipment for different aspects of biotechnology in the Department of Chemistry, School of Engineering, School of Life Sciences and Warwick Manufacturing Group.

Plant genetic modification (Life Sciences)

  • Laboratory facilities for genetic modification in Arabidopsis thaliana and Brassica napus
  • Greenhouse facilities for plant science

Microbial genetic modification (Life Sciences, Chemical Biology)

  • Laboratory facilities for genetic modification in a range of microorganisms, with particular expertise in Actinomycetes, Burkholderia, methanotrophic and methylotrophic bacteria
  • Category 2 and 3 containment facilities for microbiological work
  • Proteomic lab for protein identification
  • Genome DNA sequencing technology

Natural product isolation and structure elucidation (Chemical Biology)

  • Bioinformatics capability for predictive analysis of cryptic natural product biosynthetic gene clusters
  • Extensive facilities for growth and genetic manipulation of a wide range of microorganisms
  • Several LC-MS instruments, including UHPLC – ultra high resolution mass spectrometer for comparative metabolite profiling and dereplication
  • Several preparative HPLC systems for natural product purification
  • Ultra high resolution mass spectrometer (Bruker maXis) and high sensitivity/resolution NMR instruments (including 700 MHz with cryoprobe, 600 MHz and 500 MHz) for structure elucidation

Protein and enzyme production (Life Sciences, Chemical Biology)

  • Overproduction of microbial enzymes
  • Fermentation technology for protein production from microbial sources
  • FPLC purification of recombinant proteins
  • Enzyme kinetic characterisation using ultraviolet-visible spectroscopy, fluorescence spectroscopy and radiochemical assays

Production of bio-based chemicals (Chemical Biology)

  • Fermentation technology for chemical production from biomass
  • Lignin isolation from biomass
  • Analytical chemistry for chemical (HPLC, LC-MS) and volatile (GC-MS) identification

Fermentation and bio-separation technology (Life Sciences, Engineering)

  • 15 litre microbial fermenter with downstream separation capability
  • 270 litre microbial or solid state fermenter

Bio-based materials (Warwick Manufacturing Group)

  • Injection moulding for new bio-composites and bio-based polymers
  • Strength, fatigue and strain testing equipment for new bio-materials
  • Scanning electron microscope and optical microscope
  • Electrospinning technology

Related links

Equipment brochure (Powerpoint Presentation) 4.6mb