Antidepressant use in childhood: Evidence and implications
Sonia Bhalotra, N Meltem Daysal, and Mircea Trandafir Across the world, about 15% of children age 10-19 experience a mental health disorder (WHO 2022). Mental health disorders often begin in childhood, with half emerging by age 14 and two-thirds by age 24. If left untreated mental health disorders tend to persist, highlighting the need for early intervention. However, treatment rates are low, and it is estimated that about half of those in need do not receive treatment. Pharmacological treatment in particular has been controversial for children. New evidence from a large-scale study using Danish administrative data suggests that antidepressant treatment for children aged 8–15 with mental health needs may lead to improved long-term outcomes. These include stronger educational attainment, better employment prospects, reduced reliance on welfare benefits, and lower rates of self-harm and suicide attempts. Further analysis in this study suggests that, in Denmark, antidepressants may be under-prescribed, especially to children from families of lower socio-economic status. These findings do not rule out adverse effects which, as with any medication, can arise in a small fraction of users. However, they suggest that carefully supported treatment can improve life chances, particularly for disadvantaged children.