Skip to main content Skip to navigation

Departmental news

Project workshop addresses cyber-security in connected and autonomous mobility

Picture shows the AirQKD project trial at the University of Warwick campusResearchers from WMG, at the University of Warwick, were pleased to welcome partners and guests to a live trial and project workshop on the AirQKD project.

AirQKD addresses the cyber security of Connected and Autonomous Vehicles (CAV) and specifically addresses components, manufacturing, software, and testing for last-mile Quantum Key Distribution (QKD) systems between shared parties for 5G and connected cars.

It is an Innovate UK funded collaboration between BT; Lexden Technologies; OLC; Duality, Bristol University; Fraunhofer Centre for Applied Photonics; Strathclyde University; WMG; Bay Photonics; Heriot Watt University; Angoka; ArQit; Nu Quantum; National Physical Laboratory; CSA Catapult and Edinburgh University.

The trial combines BT’s expertise in building quantum-secure networks using QKD – an essentially un-hackable, cutting-edge technique for sharing encryption ‘keys’ between locations using a stream of single photons) with other new techniques for applying quantum security to mobile devices, developed by UK start-ups Nu Quantum, Angoka and Duality.

On the University of Warwick campus, as part of the Midlands Future Mobility testbed, WMG has created a Vehicle to Infrastructure (V2I) testing facility enabling AirQKD partners’ technology in key management, key consumption, and security protocols to be used for secure communications.

The AirQKD system implements Free Space Optics (FSO) cryptographic key generation and standards-compliant key management. WMG is now managingPicture shows AirQKD project trial on the University of Warwick campus the workstream between telecommunications (4G/5G cellular at BT’s Adastral Park site) and V2I communications on the University of Warwick campus. In combination, these technologies will be used to deliver an ultra-secure link between connected 5G towers and mobile devices, as well as to connected cars.

Find out more about CAV research at WMG here: https://warwick.ac.uk/fac/sci/wmg/research/cav/connectivity/

Read more about AirQKD here: https://warwick.ac.uk/fac/sci/wmg/research/transformation/securecybersystems/projects

 


Pre-T cell receptor localization and trafficking are independent of its signaling

Dr John James' lab have used a cellular reconstitution of preTCR function to investigate the trafficking dynamics of this developmentally important immune receptor, work which has just been published in the Journal of Cell Biology.

Expression of the pre-T cell receptor (preTCR) is an important checkpoint during the development of T cells, an essential cell type of our adaptive immune system. The preTCR complex is only transiently expressed and rapidly internalized in developing T cells and is thought to signal in a ligand-independent manner. However, identifying a mechanistic basis for these unique features of the preTCR compared with the final TCR complex has been confounded by the concomitant signaling that is normally present. Thus, we have reconstituted preTCR expression in non-immune cells to uncouple receptor trafficking dynamics from its associated signaling. We find that all the defining features of the preTCR are intrinsic properties of the receptor itself, driven by exposure of an extracellular hydrophobic region, and are not the consequence of receptor activation. Finally, we show that transitory preTCR cell surface expression can sustain tonic signaling in the absence of ligand binding, suggesting how the preTCR can nonetheless drive αβTCR lineage commitment.

Read the paper here.

Thu 03 Aug 2023, 10:36 | Tags: BMS BMS_newpub

Simple amino acids improve t-cell cryopreservation

Advanced cell-based therapies are often delivered to the patient frozen. Hence, any technology which increases the number of recovered, viable, cells post-thaw may improve clinical outcomes or allow more treatments per donation. The GibsonGroup have previously shown strategies to protect cells during freezing. In this latest work, in collaboration with Cytiva, the team show that incubating a model t-cell line with proline before cryopreservation leads to increased post-thaw cell yields. All proline is removed before cryopreservation so the actual freezing and thawing processes are unchanged. It was shown that proline limits cell proliferation, which might be contributing to its mode of action similar to ‘metabolic pre-conditioning’ which has been shown before.

Read the paper here.

Thu 03 Aug 2023, 10:33 | Tags: BMS BMS_newpub

“Perfect" Glycosylated Materials

Glycans (sugars) dictate cell-cell communication, are sites for pathogen invasion and are a key part of our immune systems. Current synthetic platforms to display glycans to investigate their biology almost always are imperfect, with heterogeneity in terms of number of glycans and the synthesis is not reproducible batch to batch. The Gibson and Ward (chemistry) groups have collaborated on a Leverhulme-Trust funded project to create ‘programmable’ glyco-clusters - before entering the lab, this method enables a research to know exactly how many glycans and their 3-D location are present on a material, and gives zero heterogeneity. This is achieved using metal co-ordination cages - 3D structures formed by spontaneous self-assembly. The team used these with model glycan-binding proteins to identify key interactions which would not be possible with traditional materials. The team are now using this to interrogate a range of targets including toxins, for diagnostics.

Read the paper here.

Thu 03 Aug 2023, 10:31 | Tags: BMS BMS_newpub

High-throughput super-resolution analysis of influenza virus pleomorphism reveals insights into viral spatial organization

Andrew McMahon and others from the Robb lab have used super-resolution imaging to study the structure of the influenza virus, work which has just been published in PLOS Pathogens.
 
Influenza virus particles are highly pleomorphic, ranging in size from spherical virions ~ 100 nm in diameter to filaments of a similar width but reaching many micrometers in length. Virus structure is of interest not only in the context of virus assembly, but also because pleomorphic variations correlate with infectivity and pathogenicity. We used a super-resolution microscopy technique called dSTORM, which takes advantage of the blinking nature of fluorophores attached to viral proteins of interest to build up images of viral particles at <20nm resolution. Andrew then imaged thousands of virus particles and studied their shape and protein organization using high throughput analysis pipelines. We found that length analysis provided a useful way of characterizing virions and investigated the arrangement of viral proteins; demonstrating that no generalized spatial frequency patterning of HA or NA on the virion surface occurs, that the NA protein is polarized to the distal tip of budding filamentous virions, and that the RNA in filamentous virions is polarized towards one end of a filament. This study demonstrates the utility of fluorescence microscopy to study virus pleomorphism, and the importance of studying viral shape and organization to investigate their effect on infection dynamics.

Read the paper here.

Thu 03 Aug 2023, 10:29 | Tags: BMS BMS_newpub

Six week 'Coding with Sophie' Programme for local primary school complete

41 primary school students have completed their six-week coding programme with colleagues in the Astronomy and Astrophysics group.

The programme ‘Coding with Sophie’ has been designed and run by Dr Rebecca Nealon and Dr Farzana MeruLink opens in a new window, with the aim to improve coding literacy and to inspire children to consider coding (and more broadly STEM) in their future, as well as empowering teachers and parents to support children in their coding journey. The opportunity to visit the University and meet real researchers aims to inspire children to believe that they can have a career in science, and that science is fun.

Read more.


Perfect Programmable Glyco-Materials

The Ward and Gibson Groups have developed 'programmable' Glycan-bearing materials, which are perfect, with no dispersity.

Mon 31 Jul 2023, 14:11 | Tags: news Synthesis and Catalysis Research news

Congratulations to the WMG Class of 2023

On Thursday 27th July, WMG celebrated the success of its latest graduates.

Picture shows WMG staff at graduation

With a total of 562 Master’s, Undergraduate, Postgraduate and Research students graduating, the team at WMG is very proud of everything the Class of 2023 has achieved.

There were 150 Undergraduate students, 76 of whom completed a Degree Apprenticeship, 73 studied full-time with one studying part-time.

For Postgraduate there were 383 Master’s students; 267 were full-time students, 31 part-time, and 85 studied overseas.

There was a further two MSCRs (Masters by Research), 22 PhD, and five EngD students.

Professor Gill Cooke, Director of Education, at WMG, University of Warwick said: “We are incredibly proud of our graduates. They have worked incredibly hard, and we hope they enjoy celebrating their achievements. We wish them all the best for the next stage of their careers.”

To find out more about studying at WMG visit https://warwick.ac.uk/fac/sci/wmg/education/


WLS student represents Team GB 7s in Leg 2 of Rugby Europe 2023

Ollie Monye, who is currently studying on our 3-year LLB degree, represented Team GB 7s in Hamburg, Germany for Leg 2 of Rugby Europe 2023. They placed 4th in the competition playing against Belgium, Lithuania, France, Germany and Ireland.

 

Mon 31 Jul 2023, 10:00 | Tags: Student Achievement, law in the community

Warwick student wins logistics research award for supply chain dissertation

Picture of Pablo Brereton RodrigoPablo Brereton Rodrigo, a School of Engineering student at the University of Warwick, has won the Logistics Research Network Undergraduate Dissertation of the Year Award 2023, from the Chartered Institute of Logistics and Transport (CILT).

Pablo has recently completed his degree in Engineering Business Management. This undergraduate degree, although part of the School of Engineering, is led by the education team at WMG, University of Warwick.

Pablo’s dissertation entitled “Integrating supply chains in a turbulent, complex and uncertain era” was nominated by Professor Rob Thornton, Director of Undergraduate Programmes, at WMG. Pablo will be presented with his certificate and prize money at the Logistics Research Network Conference (LRN 2023) dinner and awards ceremony on the 7th September 2023 at Herriot-Watt University.

Professor Thornton explained: “Pablo’s dissertation was nominated for this award, for both academic excellence and the challenging topics addressed, which are highly relevant to today’s turbulent supply chains.”

Pablo said: “In discussing topics such as supply chain integration, I explored the challenging and turbulent landscape in today’s business environment and applied it to modern-day supply chains to reach the conclusion that forward-looking firms will leverage supply chain integration through self-contained, cross-functional and digitalised many-to-many structures.

“Directly applying skills learned during my placement year in supply chains, this project has further developed my personal growth and competencies relevant to the field. As such, I am immensely grateful to my university tutor, Alexa Kirkaldy, and all my friends and family for the continued support throughout the project.”

Pablo’s research was supervised by Alexa Kirkaldy, Associate Professor and Director of Academic Integrity at WMG who said: “Pablo defined his project idea and objectives after a year in industry and was excited to delve into the topic of supply chain integration, reaching depth and breadth usually expected at Master’s level. In addition Pablo was a delight to supervise and I wish him well in his career within the semiconductor industry.”

Professor Georgia Kremmyda, Head of Teaching and Deputy Head of School of Engineering said: “On behalf of the School of Engineering and the Education team, I would like to warmly congratulate you for your amazing achievement. The award strongly highlights your effort, commitment and dedication to your studies. You should take time to celebrate what you have accomplished.”

Professor David Towers, Head of School at the School of Engineering added: “This is quite an achievement and definitely something to capture on your CV!”

To find out more please visit: WMG - The University of Warwick

Thu 27 Jul 2023, 10:44 | Tags: Education

Latest news Newer news Older news

Let us know you agree to cookies