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Genetically encoded imaging tools for investigating cell dynamics at a glance

The biology of a cell is the sum of many highly dynamic processes, each orchestrated by a plethora of proteins and other molecules.

Microscopy is an invaluable approach to spatially and temporally dissect the molecular details of these processes. Hundreds of genetically encoded imaging tools have been developed that allow cell scientists to determine the function of a protein of interest in the context of these dynamic processes. Broadly, these tools fall into three strategies: observation, inhibition and activation. Using examples for each strategy, in this Cell Science at a Glance and the accompanying poster, we provide a guide to using these tools to dissect protein function in a given cellular process. Our focus here is on tools that allow rapid modification of proteins of interest and how observing the resulting changes in cell states is key to unlocking dynamic cell processes. The aim is to inspire the reader's next set of imaging experiments.

Read the paper here.

Thu 20 Apr 2023, 13:07 | Tags: BMS BMS_newpub

The chemistry of global warming outreach style!

PhD student, Edward Lant, and Prof. Peter Sadler put on their lab coats (and matching multicoloured colour shirts!) to demonstrate the chemistry of global warming to St Nicholas Primary School childrenLink opens in a new window ,Alcester.

Thu 20 Apr 2023, 11:12 | Tags: news, Outreach

Funding awarded from Science and Technology Facilities Council

Congratulations to Dr Karolos Potamianos who has been awarded £287,845 from Science and Technology Facilities Council (STFC) for a research project titled 'Expanding the timing frontier: precision timing for particle tracking and identification.'

The funding will permit the procurement of a 12 GHz signal generator, a fast oscilloscope (<8ps per sample), and a logic analyser. These will enable the proper characterisation of ultra-fast silicon detectors and associated readout at realistic operating conditions, in particular enabling precise measurements of their (ultra-fast) response signals.

The research will be led by Dr Karolos Potamianos. He said,

"The use of fast silicon in collider detectors offers many new opportunities, as high-precision timing information enables distinguish between collisions occurring very close in space but well-separated in time. This will greatly help mitigate the effect of overlapping proton-proton interactions (pileup) at the High-Luminosity LHC. It is thus essential that we can properly characterise these detectors, which the procured equipment will enable. However, challenges such as ensuring proper operation of the detectors in a tough radiation environment and that sufficient bandwidth is available to transfer data out of the detector remain to make these detectors a reality at the LHC.”


RSC Dalton Conference comes to Warwick for 2023.

The RSC Dalton Conference came to Warwick for 2023, with 420 attendees and 130+ sessions highlighting the strength and depth of Inorganic Chemistry in the UK.

Thu 20 Apr 2023, 00:00 | Tags: Synthesis and Catalysis Research news

WMG celebrates a decade of Engineering Masterclasses

The Outreach Team, at WMG at the University of Warwick, is proud to have completed a decade of Royal Institution Engineering Masterclasses.

Over the past 10 years staff and students, from WMG, have supported 250 pupils from 45 schools across Warwickshire and the West Midlands. The Masterclasses have opened the eyes of young people to the excitement and value of engineering and, have in turn, inspired the next generation of scientists, mathematicians and engineers.

A special celebration event was held to mark the occasion with 2023 masterclass students and their families and teachers. At the event, University of Warwick alumna and award-winning engineer, Yewande Akinola delivered a key note before presenting certificates in a mini graduation ceremony.

Picture shows Professor Margaret Low at a masterclassProfessor Margaret Low, WMG’s Director of Outreach and Widening Participation said: “WMG has supported the Ri with the masterclasses, since 2013, with workshops and activities that put our cutting-edge engineering research into context for young people. We even found a way to deliver the activities online during the pandemic.

“These experiences allow students to see how their school learning applies to complicated and world-changing technologies. Through our outreach programmes we hope to inspire young people to pursue careers in STEM, widen participation in higher education and make the STEM workforce more diverse.”

Mujthaba Ahtamad (Mosh), Senior Teaching Fellow at WMG, who worked alongside Professor Margaret Low on some of the original masterclass sessions, said: “With Margaret’s enthusiasm and motivation, she really brought everything together, including inspiring the teaching team. It was really evident that the attendees were very excited to attend the Masterclasses, (perhaps more so than attending school!).”

Dr Phil Jemmett, Widening Participation Co-ordinator at WMG added: “The Royal Institution is a prestigious organisation with a long history of being at thePicture of Professor Margaret Low and Dr Phil Jemmett forefront of teaching science. Partnerships between universities in the local community, and the fact that these famous, royal-chartered groups are housed only a stone’s throw from Buckingham Palace, adds so much value to the student experience.

“This is not just an extra lesson that happens to be on a Saturday, this is an experience of just how far these students can go with their engineering talents. We hope that the students felt every bit of the prestige of both WMG and the Royal Institution.

“We would also like to thank the High Value Manufacturing Catapult who have supported these activities since 2019.”

Rachel Dorris, Clothworkers’ Fellow of Mathematics at the Royal Institution, said: “On behalf of the Royal Institution and the Masterclass team, I would like to congratulate you for successfully shepherding the Engineering Masterclasses at WMG to its 10th anniversary.

“We appreciate your hard work as an Ri collaborator - inspiring future generations within your community in the world of engineering.”

Find out more about WMG’s Outreach Programme here: Public engagement and Outreach (warwick.ac.uk)

Wed 19 Apr 2023, 16:49 | Tags: HVM Catapult Outreach

HRC Humanities Book Launch - 3rd May 2023

HRC Humanities Book Launch - Wednesday 3rd May - FAB2.25 - 11.00-14.00
I am pleased to announce the programme for this event.
We have a total of 10 presentations.
Refreshments will be available and we encourage you to bring your sandwiches.
This is a fairly informal event, and we hope you will be able to join us - there is no official booking form but as we are offering refreshments it would be useful if you could email me to confirm attendance - s.rae@warwick.ac.uk.

11.00-11.15 Alison Cooley (Classics and Ancient History)

The Senatus Consultum de Cn. Pisone Patre (Cambridge University Press, February 2023)

11.15-11.30 Emma Campbell (SMLC)

Reinventing Babel in Medieval French: Translation and Untranslatability (c. 1120–c. 1250)

(Oxford University Press, 2023)

11.30-11.45 Sarah Wood (English)

Piers Plowman and its Manuscript Tradition (York Medieval Press/Boydell & Brewer, 2022)

11.45-12.00 David Lines (SMLC)

The Dynamics of Learning in Early Modern Italy: Arts and Medicine at the University of Bologna (Harvard University Press, February 2023)

12.15-12.30 David James (Philosophy)

Property and its Forms in Classical German Philosophy (Cambridge University Press, 2023)

12.30-12.45 Carolina Bandinelli (CMPS)

Fashion as Creative Economy: Micro-Enterprises in London, Berlin and Milan (Polity, December 2022)

12.45-13.00 Chris Bilton (CMPS)

Cultural Management: a research overview (Abingdon: Routledge, 2023)

Creativities: the what, how, where, who and why of the creative process 

Bilton, Chris, Cummings, Stephen, ogilvie, dt (2022). (Cheltenham: Edward Elgar)

13.15-13.30 Clive Gray (CMPS)

The Changing Museum (Routledge, November 2022)

13.30-13.45 Jane Woddis (CMPS)

Acting on Cultural Policy: Arts Practitioners, Policy-making and Civil Society (Palgrave Macmillan, 2023).

13.45-14.00 Harry Warwick (English)

Dystopia and Dispossession in the Hollywood Science-Fiction Film, 1979-2017

(Liverpool University Press, 2023).

Wed 19 Apr 2023, 16:32 | Tags: Humanities Research Centre News

New discovery stops bacterial virus contamination

A new discovery by researchers at the University of Warwick could help stop bacteria being contaminated with viruses, reducing disruption and decreasing costs in industry and research. Read moreLink opens in a new window

Tue 18 Apr 2023, 12:58 | Tags: Polymers Research news Impact

New discovery stops bacterial virus contamination

A new discovery by Dr Antonia Sagona and colleagues could help stop bacteria being contaminated with viruses, reducing disruption and decreasing costs in industry and research.

Press Release (18 April 2023)


World Congress on Undergraduate Research

Undergraduate student, Phoebe Ryder attended the World Congress on Undergraduate Research (WorldCUR) which took place at the University of Warwick campus in early April. The WorldCUR brings together the world's best undergraduate researchers to focus on some of the most significant challenges facing the global community. The students attending are invited to share their research, discuss global issues, and create or strengthen international research partnerships.

Phoebe, a third year Physics with Astrophysics student, presented her poster on the characterisation of a binary star system that was identified as a possible supernova progenitor, with the aim of finding out whether the system had sufficient combined mass to go supernova. She said,

"It was an amazing opportunity to meet students from around the globe. There was a vast range of research being showcased and it was really inspiring and encouraging to hear others at the same educational stage to myself talk so passionately about their own research. Everyone I met was really supportive and I feel I have gained a lot of confidence in my presentation skills from the experience. Also, presenting my research to people with a wide range of previous knowledge on astrophysics, but the same enthusiasm to learn, allowed me to practice presenting to many different types of audiences.

I have learned so much from all the other delegates, about their own research and their presentation styles and techniques. I also learnt a lot from the keynote speaker, Professor Sir David Spiegelhalter's presentation. He was sharing advice on how best to communicate your research to a variety of audiences, particularly his thoughts on how to simplify your research to convey the gist without losing accuracy."


Warwick Law School colleagues gain Higher Education Academy recognition

Congratulations to Dr Rajnaara Akhtar and Dr Ana Luisa Sores Peres who have gained Higher Education Academy recognition through the Warwick Academic and Professional Pathway for Experienced Staff (APP EXP). All HEA Fellows have, through their applications, demonstrated a personal commitment to learning and teaching in higher education.

Thu 13 Apr 2023, 10:10 | Tags: Award, Staff in action

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