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Penman Group: Infectious disease epidemiology, host genetics and evolution


We know that a person’s genes can predispose them to particular diseases. However, why do human genetic differences exist at all? Natural selection from pathogens is an important selective force maintaining genetic diversity in human populations. We use mathematical models and computational simulations of evolution to understand this process. Understanding how pathogen selection drives genetic diversity in humans will offer mechanistic insights into functional differences between variants of human genes, and will also teach us new ways that we can combat infectious disease.

For all publications from the Penman group please see Publication list.

Our current research topics are shown below, but I’m happy to develop project ideas with any student who wants to apply mathematical and computational approaches to problems in infectious disease and host/pathogen co-evolution.

Current research

Group members

Connor White

Susie Cant

Mamas Louca
Grace Trivett Rachael Ralph Arthur Margolis


Dr Bridget Penman

Associate Professor, School of Life Sciences

Room 5.13, MSB | Room B137, Gibbet Hill