Owain Cisuelo

Contact

Room D229, School of Engineering of Warwick, Coventry, CV4 7AL

owain.cisuelo@warwick.ac.ukLink opens in a new window

Biography

Since graduating with a BSc in Theoretical Physics from Swansea University in 2014 I have worked as a software developer across several sectors creating scalable cloud-based solutions. From 2017-2019 I worked at a biomedical start-up developing applications to enable the smartphone as a non-invasive medical device. A key area of research was to predict blood glucose from a photoplethysmogram (PPG) signal obtained from the optical sensor. The mobile app would allow users to take a “reading” which would be analysed and provide the user with some feedback on physiological parameters such as heart rate, heart rate variability, blood pressure, and respiratory rate.

During my time there I became very interested in artificial intelligence techniques and how they can be applied to biomedical signals for the purpose of non-invasive detection of parameters that would otherwise require an invasive procedure to detect, such as blood glucose.

Research Project

My PhD project, supervised by Dr Leandro Pecchia and Dr John Hattersley, is titled “Artificial intelligence for non-invasive hypoglycaemia detection and prediction using wearable sensors”.

This project aims to develop data-driven methods to detect episodes of abnormally low blood glucose levels (hypoglycaemia) in diabetic patients by analysing the electrical activity of the heart measured non-invasively by a wearable sensor. Hypoglycaemia is a harmful complication of diabetes and insulin-dependent diabetics are more susceptible as interventions aim to achieve normal blood glucose levels. Symptoms can vary greatly and include, but not limited to, trembling, palpitations, sweating, dry mouth, confusion, seizures, coma or even death if untreated.

In collaboration with the Human Metabolism Research Unit at the University Hospitals Coventry and Warwickshire, we will recruit diabetic patients to participate in studies. The protocol will involve the wearing of a continuous glucose monitor (CGM) and electrocardiogram (ECG) device for continuous measurement and collection of blood glucose levels and ECG data. We will then use the data collected from the studies to create and evaluate AI models to predict episodes of abnormal blood glucose in diabetics.

Publications

Cisuelo, O., Stokes, K., Oronti, I.B., Haleem, M.S., Barber, T.M., Weickert, M.O., Pecchia, L., and Hattersley, J.: ‘Development of an artificial intelligence system to identify hypoglycaemia via ECG in adults with type 1 diabetes: protocol for data collection under controlled and free-living conditions’, BMJ open, 2023, 13, (4), pp. e067899
Haleem, M. S., Castaldo, R., Andellini, M., Cisuelo, O., Hattersley, J., & Pecchia, L. Estimation of ECG Parameters via Deep Learning based ECG Segmentation Tool for Non-invasive Detection of Glycaemic Events. Preprint, 2023
De Maria, C., Piaggio, D., Cisuelo, O. and Ahluwalia, A. (2022) 7. Design approaches for low resource settings, In Biomedical engineering for sustainable development, Gruppo nazionale di bioingegneria, Bologna, Pàtron Editore, pp. 109–121.
Piaggio, D., Cisuelo, O., Su, W., Andellini, M. and Pecchia, L. (2022) 10. Use of smartphones for frugal innovation, In Biomedical engineering for sustainable development, Gruppo nazionale di bioingegneria, Bologna, Pàtron Editore, pp. 155–166.

Awards

International Federation for Medical and Biological Engineering (IFMBE) Young Investigator Competition Second Prize for presenting the paper 'Spectrogram-driven Convolutional Neural Network for Real-Time Non-invasive Hyperglycaemia Detection in Paediatric Type-1 Diabetes via Wearable Sensors'. Mediterranean Conference on Medical and Biological Engineering and Computing and International Conference on Medical and Biological Engineering, Sarajevo, Bosnia-Herzegovina, September 2023

Receiving the IFMBE Young Investigator second prize at MEDICON 2023