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CRiSM Seminar

Location: A1.01

Prof. Galin Jones, School of Statistics, University of Minnesota (14:00-15:00)

Bayesian Spatiotemporal Modeling Using Hierarchical Spatial Priors, with Applications to Functional Magnetic Resonance Imaging

We propose a spatiotemporal Bayesian variable selection model for detecting activation in functional magnetic resonance imaging (fMRI) settings. Following recent research in this area, we use binary indicator variables for classifying active voxels. We assume that the spatial dependence in the images can be accommodated by applying an areal model to parcels of voxels. The use of parcellation and a spatial hierarchical prior (instead of the popular Ising prior) results in a posterior distribution amenable to exploration with an efficient Markov chain Monte Carlo (MCMC) algorithm. We study the properties of our approach by applying it to simulated data and an fMRI data set.

Dr. Flavio Goncalves, Universidade Federal de Minas Gerais, Brazil (15:00-16:00).

Exact Bayesian inference in spatiotemporal Cox processes driven by multivariate Gaussian processes

In this talk we present a novel inference methodology to perform Bayesian inference for spatiotemporal Cox processes where the intensity function depends on a multivariate Gaussian process. Dynamic Gaussian processes are introduced to allow for evolution of the intensity function over discrete time. The novelty of the method lies on the fact that no discretisation error is involved despite the non-tractability of the likelihood function and infinite dimensionality of the problem. The method is based on a Markov chain Monte Carlo algorithm that samples from the joint posterior distribution of the parameters and latent variables of the model. The models are defined in a general and flexible way but they are amenable to direct sampling from the relevant distributions, due to careful characterisation of its components. The models also allow for the inclusion of regression covariates and/or temporal components to explain the variability of the intensity function. These components may be subject to relevant interaction with space and/or time. Real and simulated examples illustrate the methodology, followed by concluding remarks.

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