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Personalized Chronomodulated 5-Fluorouracil Treatment: A Physiologically Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy

This work is based on the discovery of diurnal variations impacting cancer therapy. Especially, use of chronomodulated treatment with 5-fluorouracil (5-FU) has gained significance. Studies indicate high inter-individual variability in diurnal variations in dihydropyrimidine dehydrogenase (DPD) activity – a key enzyme for 5-FU metabolism. However, the influence of individual chronotypes on chronomodulated therapy was unclear but is needed to optimize precision dosing of chronomodulated 5‑FU. Lead by the Thorsten Lehr's PKPD group at the University of Saarland, this collaborative paper is taking a treasure trove of patient 5-FU PK data amalgamated with DPD enzyme activity data from health people to establish a novel PKPD model of 5-FU that captures the extent of diurnal variations in DPD activity and can help investigate individualized chronomodulated 5-FU therapy through testing alternative personalized dosing strategies. Read the paper here.

Thu 25 Jan 2024, 08:50 | Tags: BMS BMS_newpub

WLS Staff Spotlight: Professor Christian Twigg-Flesner

This week, we were delighted to interview Professor Christian Twigg-Flesner, Deputy HoD and Director of Teaching and Learning, for our Warwick Law School Staff Spotlight series.

Wed 24 Jan 2024, 12:00 | Tags: WLS Staff Spotlight

Securing the future of offshore infrastructure - major training grant for Warwick Academic

Professor Xueyu Geng secures funding as part of a major EU consortium.

Wed 24 Jan 2024, 09:00 | Tags: PEATER Civil Engineering Research Women in Engineering

PhD Student, Satarupa Das, attends GYSS 2024

Satarupa, a PhD student under the supervision of Prof Richard Walton, met with students and distinguished speakers from around the world at this prestigious event. tinyurl.dev/mrxbjkdb


Labour leader sees University of Warwick’s industrial impact first hand

Keir Starmer visits WMG at the University of Warwick Keir Starmer today visited WMG at the University of Warwick to meet researchers, technicians, and students at one of the world’s leading centres for industrial innovation and skills.

He was joined by Labour’s mayors and mayoral candidates, including Richard Parker (West Midlands), Andy Burnham (Greater Manchester) and Claire Ward (East Midlands).

The Labour leader and the mayors visited WMG’s International Manufacturing Centre (IMC), where Warwick experts work with industrial partners to drive forward innovation in fields such as sustainable transport, connected and autonomous vehicles, agritech and advanced manufacturing.

WMG is an academic department within the University and is widely regarded as an international role model for successful collaboration between academia and the public and private sectors, driving innovation in science, technology, and engineering.

Keir met with the University’s Vice-Chancellor, Professor Stuart Croft, and the Dean of WMG, Professor Robin Clark, and had an opportunity to see innovative projects such as Warwick Racing, Warwick Moto, and the Driving the Electric Revolution programme for novel electric motors for use in electric transport.

Kier Starmer visits WMG at the University of WarwickSpeaking after the visit, Keir said: "I was delighted to visit WMG at the University of Warwick today to hear about their pioneering work to drive growth through its support for business and industry. We need the UK’s universities to be central to our future economic growth, through their contributions to innovation, sustainability, and the talents of our people.

"Meeting some of the University’s impressive researchers, technicians and students, who are working on the technology of the future, their driving purpose is what an incoming Labour government will bring, if we are privileged enough to serve. We’ll work hand in hand with universities, sixth forms and further education colleges to deliver on each of our five missions to give Britain its future back.”

Vice Chancellor, Professor Croft said: “We were pleased to host the Labour leader and the mayors and mayoral candidates to show them some of the cutting-edge research and product development which takes place here on our campus.

“The University of Warwick is unique with respect to the way it has worked hand-in-glove with industry and businesses for decades, developing innovative products and services with them and finding real-world solutions to complex problems. Collaboration, openness, and creativity is at the heart of our approach, which has led to a host of breakthrough technologies and innovations.”

Dean of WMG, Professor Robin Clark, added: “At WMG, we focus on working with industry to create real innovation to drive growth in our economy, and give people the practical skills to make a difference to the world around them. It was a pleasure to introduce Keir to our researchers, technicians and students who are really helping make our country more sustainable, safer, and prosperous.”

The University of Warwick is ranked as one of the world’s best universities, with 92% of its research rated as world-leading or internationally excellent.

Fri 19 Jan 2024, 14:28 | Tags: HVM Catapult People Impacting society

We are seeking to support talented candidates for UKRI FLF Round 9

Warwick Chemistry is seeking to support talented candidates for the UKRI Future Leaders Fellowships - Round 9. Expression of Interest Due 19 February. tinyurl.com/2rjjkuru

Thu 18 Jan 2024, 11:17 | Tags: news Research news

Professor Jane Bryan listed as one of the winners in the Positive Leadership Awards 2023

We are excited to share that Warwick Law School’s Professor Jane Bryan has been listed as one of the official winners of the second edition of the Positive Leadership Awards.

Thu 18 Jan 2024, 11:00 | Tags: Award, Staff in action

Winners of the MSc prizes

The department congratulates all 2022-2023 MSc students graduating in January 2024. Extra congratulations to the winners of the following MSc prizes:

Luisa F. Estrada Plata: Best dissertation in MSc Data Analytics & Best overall performance (MSc Data Analytics)

Aakash Chandnani: Best overall performance (MSc Computer Science)

Yijie Zhu: Best dissertation in MSc Computer Science

Weitong Liao: Best dissertation in MSc Computer Science

Thu 18 Jan 2024, 10:36 | Tags: Courses Highlight Faculty of Science Teaching

WMG graduates shine at the University of Warwick's Winter Graduation Ceremonies

Congratulations are in order for the accomplished individuals of WMG who marked a significant milestone at the University of Warwick's Winter Graduation Ceremonies this week.

A total of 1,381 Master's, Postgraduate Research and Undergraduate students graduated from across WMG.

There were 1,225 Master’s students; 1,072 were full-time, 35 part-time, and 118 studied overseas.

Twelve graduated from the Postgraduate research programme including 11 PhD students and one Master’s of Science by research student.

A total of 144 were undergraduate students; three graduated with a BSc in Cyber Security, one with a BSc in Digital Healthcare Science; two with a BEng in Automotive Engineering and the remaining 138 were Degree Apprenticeship students.

At the WMG graduation event, the alumni speeches delivered by esteemed speakers, Philomena Lavery (MSc Cyber Security and Management, 2020), and Dr. Benjamin Wood, (MEng Mechanical Engineering, 2006; EngD Engineering, 2012) were nothing short of inspiring. Their words not only resonated with wisdom but also ignited a sense of motivation and empowerment among the graduates.

Philomena Lavery, Senior Vice President Digital Security at AVEVA, and Dr. Benjamin Wood, Director, Research & Technology – Manufacturing Innovation at Hexcel Corporation, brought a unique blend of expertise and experience to the podium. Their heartfelt messages added an extra layer of significance to the celebration, leaving a lasting impression on all who attended.

Professor Robin Clark, Dean of WMG, said, “Congratulations to all our graduates. Your dedication and remarkable achievements have not only sculpted your academic journey but have also enriched the vibrant and innovative community here at WMG.

“I take immense pride in your accomplishments, and they stand as a testament to your resilience and commitment to excellence. I hope you continue to reach for new heights and inspire those around you now and in the future. Well done!”

Professor Steve Maggs, Director of Alumni and Industry Engagement, added: “As these graduates embark on new horizons, we celebrate their remarkable journey and commend their dedication. With a total of 1,381 Master’s, Postgraduate Research and Undergraduate students, this class not only signifies academic prowess but also adds depth to our diverse community.”

Professor Steve Maggs, further says, “At the University of Warwick, connections do not end when our students graduate; you join a community like no other. As a Warwick graduate, you become part of a global community of more than 285,000 alumni in more than 180 countries and territories, with over 29,000 of those who are WMG graduates. Wherever you are in the world, you can keep connected with the friends and networks developed during your studies and also have the opportunity to make new connections.”

Check out the WMG alumni web pages for more details: https://warwick.ac.uk/alumni

To find out more about studying at WMG visit: Study | WMG | University of Warwick

 


WMG hosts scholarship celebration event

Picture shows Dr Jane Marshall with WMG students at the Scholarship DinnerWMG at the University of Warwick was pleased to host its annual Scholarship Dinner celebration for full-time Master’s students last week.

This academic year, WMG has welcomed a total of 225 scholarship students from across 45 different countries. The event was a chance to celebrate the achievements of the students and give them an opportunity to network with staff and peers.

The WMG Excellence Scholarship - a competitive, merit-based scholarship through which WMG provides tuition fee discounts to particularly strong applicants - was awarded to 130 of the students.

A further 23 students received a Chevening Scholarship funded by the UK Government Foreign, Commonwealth and Development Office. Chevening Scholarships are widely considered one of the top scholarships for Master’s degrees, making them extremely prestigious and highly competitive.

The remaining 72 students received scholarships from partner sponsors from UK and international funding bodies including governments, charities, development funds, industry, and banks.

Professor Dan Nunan, Director of Full Time Postgraduate Programmes, who hosted the celebration event explained: “The annual scholarship dinner for MSc students was the biggest ever with nearly all of our 225 scholars attending.

“We are very grateful to the many external organisations who provide funding, sponsorship and other forms of financial support that enable students, who would not otherwise be able to study at Warwick, to attend. This year around £5m will be provided in scholarships and other support to students at WMG. Having this support is key in enabling WMG to continue to attract the best, and highest potential, students from all around the world.”

Cathy Fawcett, Student Recruitment and Marketing Manager at WMG, and organiser of this event commented: “It’s so gratifying bringing together all our scholars for a celebration like this. For so many, joining Warwick is the culmination of several years’ effort as the competition, particularly for awards like Chevening, is immense. A special thanks to the staff - course leaders, representatives and others who did a fantastic job of hosting tables and making this a really special occasion for our scholars.”

If you’re interested in studying for a postgraduate course at WMG, find out more here about the range of Master’s programmes across engineering, technology, digital, management and business.

Take a look at the WMG scholarship opportunities here: https://warwick.ac.uk/fac/sci/wmg/study/masters-degrees/how-to-apply/finance/

Wed 17 Jan 2024, 17:15 | Tags: Education Full time Master's Programme

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