Advances in imaging and computational techniques are enabling researchers to discover more than ever before about health and disease at cellular and molecular levels, whether observing cell structures with ultra precision, imaging biological processes in real-time or studying disease mechanisms.

Advanced imaging is crucial in applications ranging from diagnostics to drug development. It can be used by scientists and clinicians to identify structural and functional abnormalities in diseased cells, study how pathogens and drugs interact with cells and tissues, and analyse biopsy samples.

The Computing and Advanced Microscopy Development Unit (CAMDU) at Warwick Medical School houses cutting-edge imaging systems and powerful analytical resources that are driving innovation in biomedical and medical science.

Challenges in industry and research

Understanding complex biological systems, from cellular processes to tissue dynamics, demands high-resolution, multidimensional imaging and precise data analysis.

The nature of biological samples, including live cells and tissues, presents unique challenges for scientists. For example, capturing the rapid dynamics of cellular interactions requires imaging systems capable of producing detailed, high-resolution images in real-time while minimising bleaching or toxicity from light exposure.

Additionally, data generated from advanced imaging methods are often vast and complex, requiring specialised computational infrastructure and expertise for meaningful analysis.

Work with Warwick to help you drive innovation

CAMDU’s imaging and computational capabilities include:

• Lattice light sheet microscope: a cutting-edge imaging system that provides 3D imaging of live cells with high resolution and minimal phototoxicity. This technology enables researchers to visualise rapid cellular processes, such as protein dynamics and cytoskeletal changes, in unparalleled detail.
• Spinning disk confocal microscopes: high-speed, high-resolution imaging with optical sectioning capabilities for thick samples, ideal for imaging complex three-dimensional structures in real time. Applications include neuroanatomy and stem cell research.
• Widefield fluorescence microscopes: This is a widely used biological imaging technique that captures emitted fluorescent light from fluorophores to generate high-contrast images. It is ideal for fast imaging and observing living cells and dynamic processes with minimal photodamage.
• Quantitative phase imaging: a powerful optical imaging technique that provides quantitative information on samples without the need for fluorescent dyes or stains.
• Advanced computational analysis: CAMDU hosts a suite of workstations capable of handling large datasets and complex image analysis pipelines, including 3D visualisations.

For detailed specifications of our instruments and computational resources, visit the CAMDU website and our Analytical Capability Guide.

Why Warwick?

Advanced Equipment and Integration: CAMDU’s advanced imaging technologies are part of Warwick’s extensive network of research facilities, enabling easy access to complementary analysis techniques.

World-Class Data Service: CAMDU’s data services go beyond imaging. Our computational experts offer advanced analysis, from 3D visualisation to machine learning-powered insights, providing actionable results.

Expertise: CAMDU is operated by a team of highly experienced imaging specialists who provide comprehensive support and user training tailored to the needs of diverse research projects.

Ease of Access: CAMDU’s facilities are available for external users to access through Warwick Scientific Services. Our secure online portal facilitates quick turnaround of contracting processes, including NDA and MTA agreements

Success stories at Warwick

CAMDU has supported numerous external collaborators to drive advances in medical research. Its computational facilities have enabled advanced analysis of imaging data, from 3D reconstructions to machine learning-based pattern recognition. These tools have supported research in drug discovery, tissue engineering, and diagnostics, showcasing the integration of computational expertise with imaging technologies.

CAMDU also runs a Visitor Programme that provides external researchers with access to the Wellcome-funded Lattice LightSheet Microscope. Visit the CAMDU website to learn more about our collaborations.

Contact us

Get in touch to discuss how we can help you solve challenges. Contact Claire Gerard, Warwick Scientific Services Manager: .