Preprints

2025

Andreas Zaucker, Maria Papafoti, David Corcoran, DaeNia Shawn La Rode, Rebecca Leech, Pavle Vrljicak, Pooja Kumari, Karuna Sampath (2025) In toto imaging of germ plasm dynamics reveals an essential role for early distribution of germ granules in germline development BioRxiv doi.org/10.1101/2025.02.26.640298
Alexandra Lovatt, Ashvini Wijayapala, Macy Mui, Jack Butler, Nicholas Dale (2025) Connexin 50 hemichannels are opened by CO₂: implications for lens physiology. BioRxiv doi.org/10.1101/2025.01.23.634273
Valentin-Mihai Dospinescu, Alexander Mascarenhas, Jack Butler, Sarbjit Nijjar, Kyara de Oliveira Taborda, Sean Connors, Lumei Huang, Nicholas Dale (2025) CO2-dependent opening of Connexin 43 hemichannels BioRxiv doi.org/10.1101/2025.01.13.632711
Will Scott, Vitaliia Polutranko, Ian Hands-Portman, Mohan K Balasubramanian (2025) Fluorescent protein tags for human tropomyosin isoform comparison. BioRxiv doi.org/10.1101/2025.02.25.640032

2024

Scott Brooks, Sara Toral-Perez, David S Corcoran, Karl Kilborn, Brian Bodensteiner, Hella Baumann, Nigel J Burroughs, Andrew D McAinsh, Till Bretschneider (2024) CelFDrive: Artificial Intelligence assisted microscopy for automated detection of rare events BioRxiv doi: 10.1101/2024.10.17.618897Link opens in a new window.
Will Scott, Esther Ivorra-Molla, Dipayan Akhuli, Teresa Massam-Wu, Jonathan Cook, Lijiang Song, Masanori Mishima, Allister Crow, Mohan K. Balasubramanian (2024) StayRose: a photostable StayGold derivative red-shifted by genetic code expansion BioRxiv doi.org/10.1101/2024.12.13.628370
Danielle Groves, Rory Cunnison, Andrew McMahon, Haitian Fan, Jane Sharps, Adrian Deng, Jeremy R Keown, Ervin Fodor, Nicole C Robb (2024) Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET, BioRxiv doi: 10.1101/2024.10.15.618435Link opens in a new window.
Lindsey S. Marmont, Anna K. Orta, Robin A. Corey, David Sychantha, Ana Fernández Galliano, Yancheng E. Li, Becca W.A. Bailey, Neil G. Greene, Phillip J. Stansfeld, William M. Clemons Jr., Thomas G. Bernhardt. A feedback control mechanism governs the synthesis of lipid-linked precursors of the bacterial cell wall BioRxiv doi: 10.1101/2023.08.01.551478Link opens in a new window.
McIntyre I., Vasilyev V., Perrone CL., Dhami P., Panir K., Rosser M. & Greaves E. (2024). Preclinical testing of RRx-001 in mouse models of experimental endometriosis reveals promising therapeutic impacts. BioRxiv doi: 10.1101/2024.08.12.607591v1Link opens in a new window.
Bafna, A., Banks, G., Vasilyev, V., Dallmann, R., Hastings, MH. & Nolan, PM. (2024) Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus. BioRxiv doi.org/10.1101/2023.11.23.568399Link opens in a new window.
Johal, S., Elsayed, R., Panfilio, K.A., Andrew C. Nelson (2024) Identifying the molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish. BioRxiv doi.org/10.1101/2024.02.06.579092
Inman, A., Lutton, J.E., Spiritosanto, E., Tada, M., Bretschneider, T., Haas, P.A., Smutny, M. (2024) A multi-tiered mechanical mechanism shapes the early neural plate. BioRxiv doi.org/10.1101/2023.06.21.545965
Henlon, Y., Panir, P., McIntyre, I., Hogg, C., Dhami, P., Cuff, A.O., Senior, Moolchandani-Adwani, N., Courtois, E.T., Horne, A.W., Rosser, M., Ott, S., & Greaves, E., (2024) Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic niche. BioRxiv doi.org/10.1101/2024.03.07.583861
Fesenko, M., Moore, D., Ewbank, P., & Royle, S.J. (2024) ATG9 vesicles are a subtype of intracellular nanovesicle BioRxiv doi.org/10.1101/2024.09.12.612637

2023

Vlachou D., Veretennikova M., Usselmann L., Vasilyev V., Ott S., Bjarnason GA., Dallmann R., Levi FA., Rand DA. (2023) TimeTeller: a tool to probe the circadian clock as a multigene dynamical system. bioRxiv, DOI: 10.1101/2023.03.14.53217Link opens in a new window.
Yean Ming Chew & Robert A. Cross (2023) Taxol acts differently on different tubulin isotypes. bioRxiv DOI: 10.1101/2023.02.07.527540
Esther Ivorra-Molla, Dipayan Akhuli, Martin B.L. McAndrew, William Scott, Lokesh Kumar, Saravanan Palani, Masanori Mishima, Allister Crow, Mohan K. Balasubramanian (2023) A monomeric StayGold fluorescent protein, Nature Biotechnology doi.org/10.21203/rs.3.rs-2684100/v1
Hill, E., Huang, X., Del Popolo, I., La Mache, C., Lochner, M., Ladds, G., Frenguelli, B.G. and Wall, M.J. (2023) Species-dependent actions of the Goαb selective adenosine A₁ receptor agonist BnOCPA. BioRxiv doi.org/10.1101/2022.12.02.518704
Warren, M.T., Biggs, C,I,, Bissoyi A,, Gibson, M.I. and Sosso, G.C. (2023) Data-driven Discovery of Potent Small Molecule Ice Recrystallisation Inhibitors. ChemRxiv. DOI: 10.26434/chemrxiv-2023-gvvk0
Abid Ali, F.*, Zwetsloot, A.J.*, Stone, C.E., Morgan, T.E., Wademan, R.F., Carter, A.P.* and Straube, A.* (2023) KIF1C activates and extends dynein movement through the FHF cargo adaptor BioRxiv doi.org/10.1101/2023.10.26.564242

2022

Tailise Carlina de Souza-Guerreiro, Gaia Bondelli, Iago Grobas, Stefano Donini, Valentina Sesti, Chiara Bertarelli, Guglielmo Lanzani, Munehiro Asally & Giuseppe M Paterno (2022) Membrane Targeted Azobenzene Drives Optical Modulation of Bacterial Membrane Potential. bioRxiv, DOI: 10.1101/2022.09.05.506195Link opens in a new window.
Chelsea M Brown, Robin A. Corey, Ya Gao, Yeol Kyo Choi, Martine Gilleron, Nicolas Destainville, Elizabeth Fullam, Wonpil Im, Phillip James Stansfeld & Matthieu Chavent (2022) From Molecular Dynamics to Supramolecular Organization: The Role of PIM Lipids in the Originality of the Mycobacterial Plasma Membrane. bioRxiv, DOI: 10.1101/2022.06.29.498153Link opens in a new window.
Tomoyuki Hatano, Tzer Chyn Lim, Ingrid Billault-Chaumartin, Anubhav Dhar, Ying Gu, Teresa Massam-Wu, Sushmitha Adishesha, Luke Springall, Lavanya Sivashanmugam, William Scott, Masanori Mishima, Sophie G Martin, Snezhana Oliferenko, Saravanan Palani, Mohan K. Balasubramanian. mNeonGreen-tagged fusion proteins and nanobodies reveal localization of tropomyosin to patches, cables, and contractile actomyosin rings in live yeast cells. bioRxiv, DOI: 10.1101/2022.05.19.492673Link opens in a new window.
Lewis Taylor, Felix von Lendenfeld, Anna Ashton, Harshmeena Sanghani, Eric Tam, Laura Usselmann, Maria Verennetikova, Robert Dallmann, Jane McKeating, Sridhar Vasudevan & Aarti Jagannath (2022) Sleep and circadian rhythm disruption alters the lung transcriptome to predispose to viral infection. bioRxiv, DOI: 10.1101/2022.02.28.482377 Link opens in a new window .
Harrington, NE, Allen, F, Garcia Maset, R & Harrison, F (2022) Pseudomonas aeruginosa transcriptome analysis in a cystic fibrosis lung model reveals metabolic changes accompanying biofilm maturation and increased antibiotic tolerance over time. BioRxiv 2022.06.30.498312

2021

Sarah M. Smith, Gabrielle Larocque, Katherine M. Wood, Kyle L. Morris, Alan M. Roseman, Richard B. Sessions, Stephen J. Royle & Corinne J. Smith (2021) Multi-modal adaptor-clathrin contacts drive coated vesicle assembly, bioRxiv, DOI: 10.1101/2021.05.22.445240Link opens in a new window.
Nida Siddiqui, Daniel Roth, Algirdas Toleikis, Alexander J. Zwetsloot, Robert A. Cross, Anne Straube. Force generation of KIF1C is impaired by pathogenic mutations. BioRXiv, doi: 10.1101/2021.06.30.450611Link opens in a new window.
Rebekah A. Jones, Holly Shropshire, Caimeng Zhao, Andrew Murphy, Ian Lidbury, Tao Wei, David J Scanlan & Yin Chen. Phosphorus stress induces the synthesis of novel glycolipids in Pseudomonas aeruginosa that confer protection against a last-resort antibiotic. BioRXiv, DOI: 10.1101/2021.04.14.439775Link opens in a new window.
Ciearra B. Smith, Vincent van der Vinne, Eleanor McCartney, Adam C. Stowie, Tanya L. Leise, Blanca Martin-Burgos, Penny C. Molyneux, Lauren A. Garbutt, Michael H. Brodsky, Alec J. Davidson, Mary E. Harrington, Robert Dallmann & David R. Weaver. Cell-type specific circadian bioluminescence rhythms recorded from Dbp reporter mice reveal circadian oscillator misalignment. BioRXiv, DOI:10.1101/2021.04.04.438413 Link opens in a new window.
Thomas M Rawlings, Komal Makwana, Deborah M Taylor, Matteo A Mole, Katherine J Fishwick, Maria Tryfonos, Joshua Odendaal, Amelia Hawkes, Magdalena Zernicka-Goetz, Geraldine Hartshorne, Jan Brosens & Emma S Lucas. Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids. BioRXiv, DOI: 10.1101/2021.03.02.433560Link opens in a new window.

2020

Maria Diniz-da-Costa, Chow-Seng Kong, Katherine J Fishwick, Thomas Rawlings, Paul John Brighton, Amelia Hawkes, Joshua Odendaal, Siobhan Quenby, Sascha Ott, Emma S Lucas, Pavle S Vrljicak, Jan J Brosens (2020) Characterization of highly proliferative decidual precursor cells during the window of implantation in human endometrium. BioRxiv, DOI: 10.1101/2020.12.16.423007Link opens in a new window.
Larocque G., La-Borde GJ., Wilson BJ., Clarke NI., Moore DJ., Caswell PT. & Royle SJ. (2020) Intracellular nanovesicles mediate integrin trafficking during cell migration. BioRXiv, DOI: 10.1101/2020.08.19.257287Link opens in a new window.
Lanza B. & Parashar D. (2020) Do Support Vector Machines play a role in stratifying patient population based on cancer biomarkers? BioRXiv, doi: 10.1101/2020.11.02.364612Link opens in a new window.
Talbot CD., Walsh MD., Cutty SJ., Elsayed R., Bruce AEE., Wardle FC. & Nelson AC. (2020) Eomesodermin is functionally conserved between zebrafish and mouse in spite of different mutant phenotypic severities, and controls left/right organiser formation via interlocking feedforward loops. BioRXiv, DOI: 10.1101/2020.10.02.324244Link opens in a new window.
Amol Bhandare, Joseph van de Wiel, Reno Roberts, Ingke Braren, Robert Huckstepp & Nicholas Dale (2020) Analyzing the neuroglial brainstem circuits for respiratory chemosensitivity in freely moving mice. BioRXiv, DOI: 10.1101/492041Link opens in a new window.
Iago Grobas, Marco Polin, Munehiro Asally (2020) Swarming bacteria undergo localized dynamic phase transition to form stress-induced biofilms. BioRXiv, DOI:10.1101/2020.08.11.243733Link opens in a new window.
Joseph Van de Wiel, Louise Meigh, Amol Bhandare, Jonathan Cook, Sarbjit Nijjar, Robert Huckstepp, Nicholas Dale (2020) Connexin26 mediates CO2-dependent regulation of breathing via glial cells of the medulla oblongata. BioRXiv, DOI: 10.1101/2020.04.16.042440Link opens in a new window.
Mark J. Wall, Emily Hill, Robert Huckstepp, Kerry Barkan, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Ian Winfield, Haifeng Wei, Wendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, Graham Ladds, Bruno G. Frenguelli (2020) A biased adenosine A1R agonist confers analgesia without cardiorespiratory depression. BioRXiv, DOI: 10.1101/2020.04.04.023945Link opens in a new window.
Alexander N. Baker, Sarah-Jane Richards, Collette S. Guy, Thomas R. Congdon, Muhammad Hasan, Alexander J. Zwetsloot, Anne Straube, Marc Walker, Simona Chessa, Giulia Pergolizzi, Simone Dedola, Robert Field, Matthew Gibson (2020) The SARS-COV-2 Spike Protein Binds Sialic Acids, and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device. ChemRxiv. DOI: 10.1021/acscentsci.0c00855Link opens in a new window

2019

Charmet, J.; Rodrigues, R.; Yildirim, E.; Challa, P.K.; Roberts, B.; Dallmann, R. & Whulanza, Y. (2019) Low Cost Microfabrication Tool Box. Preprints, Accession Number: 2019120371Link opens in a new window.
Emanuele Roscioli, Tvetselina Germanova, Chris A. Smith, Peter A. Embacher, Muriel Erent, Amelia I. Thompson, Nigel J. Burroughs & Andrew D. McAinsh (2019) Ensemble-level organization of human kinetochores and evidence for distinct tension and attachment sensors. BioRxiv 685248, DOI: 10.1101/685248Link opens in a new window.
Arnaud Kengmo Tchoupa, Rebekah A Jones, Agnes Kuroki, Mohammad Tauqeer Alam, Sebastien Perrier, Yin Chen & Meera Unnikrishnan (2019) The type VII secretion system protects Staphylococcus aureus against antimicrobial host fatty acids. BioRXiv, DOI: 10.1101/572172v1Link opens in a new window.
Sylvain Durand, Adam Callan-Sidat, Josie McKeown, Stephen Li, Gergana Kostova, Juan R. Hernandez-Fernaud, Mohammad Tauqeer Alam, Andrew Millard, Chrystala Constantinidou, Ciarán Condon, Emma L. Denham (2019) Novel regulation from novel interactions: Identification of an RNA sponge that controls the levels, processing and efficacy of the RoxS riboregulator of central metabolism in Bacillus subtilis. BioRXiv, DOI: 10.1101/814905 Link opens in a new window.
Vlisidou, I., Hapeshi, A., Healey, J.R.J., Smart, K.,Yang G. & Waterfield, N.R. (2019) Photorhabdus Virulence Cassettes: extracellular multi-protein needle complexes for delivery of small protein effectors into host cells. BioRXiv, DOI: 10.1101/549964v1Link opens in a new window.

2018

Nida Siddiqui, Alice Bachmann, Alexander James Zwetsloot, Hamdi Hussain, Daniel Roth, Irina Kaverina & Anne Straube (2018) Activation of intracellular transport by relieving KIF1C autoinhibition. BioRXiv, DOI: 10.1101/488049Link opens in a new window