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NIHR Statistics Group: Imaging Studies section - April Meeting

Statistical Issues in Clinical Trials of Inflammatory Bowel Disease using Endoscopy

Monday 27th April 2015, 12-4pm, Scarman House Conference Centre, University of Warwick

This meeting will bring together statisticians, clinicians and other methodologists for discussion of common statistical issues in imaging studies. Challenges will be illustrated by examining a clinical example – centralised reading of endoscopy for clinical trials in Inflammatory Bowel Disease – but they are also widely applicable to other imaging modalities. Statistical issues for discussion in this meeting will include:

  • Sample size considerations in imaging studies
  • Inter-rater agreement and the effect of subjective image assessment
  • Reproducibility of endpoint assessment
  • Agreement and variability between repeated imaging time-points

Getting here

Please see the Warwick Conferences How to find us page for directions. In summary:

By car The University of Warwick is located just outside of Coventry (not near Warwick). Please see this Google Map for the exact location of the Scarman building; it's on Scarman Road, sign posted from Gibbet Hill road. For satnavs, the post code for all of campus is CV4 7AL; the exact entrace to Scarman is at 52.382049,-1.566905. Parking is freely available right at Scarman.
By train Get yourself to Coventry station. Taxis from the station cost about £10 and take about 15 mins. Ask for University of Warwick, Scarman building (on Scarman Road, sign posted from Gibbet Hill road).


12:00 Registration and Lunch
13:00 Introduction and Overview
Tom Fanshawe (Nuffield Department of Primary Care Health Sciences, University of Oxford) & Sue Mallett (School of Health and Population Sciences, University of Birmingham)
13:15 Centralised Reading of Endoscopy for Clinical Trials in Inflammatory Bowel Disease
Clinical Challenges – Vip Jairath, NIHR Clinical Trials Fellow (Oxford Clinical Trial Research Unit) and Clinician in Gastroenterology and Inflammatory Bowel Disease (John Radcliffe Hospital, Oxford)
14:00 Statistical Challenges – initial group discussion
14:20 Coffee and Networking
14:50 Structured Discussion of Statistical Issues
Led by Susan Dutton & Vicky Strauss (Senior Medical Statisticians, Oxford Clinical Trial Research Unit and Centre for Statistics in Medicine, University of Oxford)
15:45 Summary and Close


Attendees should register using this EventBrite invitation.

Places are limited and will be allocated on a first-come, first-served basis.

This event is free of charge, and attendees should plan to arrive promptly at 12 noon to enjoy the sit-down carvery lunch and ample time for networking. For more information, email Tom Fanshawe.

To join the NIHR Statistics Group for information about future events, email:


This event includes lunch, parking and refereshments at no cost, thanks to generous support from

Attendees from the West Midlands are kindly asked to consider joining the West Midlands Health Informatics Network; please click here for more information.