Skip to main content Skip to navigation

Spatiotemporal Reconstruction of List Mode PET

Joint work by
 
Thomas Nichols
Department of Biostatistics, University of Michigian
Jinyi Qi
Center for Functional Imaging, Lawrence Berkley National Laboratory, UC Berkley
Evren Asma & Richard Leahy
Signal and Image Processing Institute, University of Southern California





List Mode Movie (542KB MPEG)

This is an estimate of the dynamic distribution of [15]-O labeled water, after the injection of a 5 milliCurie bolus. This axial slice passes through the cerebellum and the inferior temporal poles; it captures the early, transient passage of activity through the internal carotid artery (petrous part), as well as the build up of tracer in cerebellar and brain tissue.

Relative to usual conventions the image is upsidedown, posterior at the top of the image, anterior at the bottom.



Full volume List Mode Movie (139KB MPEG)

This is the same data as above, but now all slices of the brain have been reconstructed and we use a different visualization method. We view the subject from the side and set him rotating; the blue colored region indicates the outline of the head. In red we see the spatiotemporal distribution of the [15]-O-water tracer in the carotid artery and, subsequently, throughout the brain.

This movie represents approximately 20 seconds in real time.

 



Raclopride list mode movie (2MB MPEG)

This is an estimate of the dynamic distribution of [11]-C Raclopride, a dopamine ligand. Note how initially the distribution is nearly uniform throughout the brain, while subsequently the tracer only collects in the striatum.

This movie represents 90 minutes of data; note the slow shifting of the head to the left and right indicating subject motion.

Relative to usual conventions the image is upsidedown, posterior at the top of the image, anterior at the bottom.


 

Neuroimaging
Statistics

[brain]


Contact Info

Room D0.03
Deptment of Statistics
University of Warwick
Coventry
CV4 7AL
United Kingdom

Tel: +44(0)24 761 51086
Email: t.e.nichols 'at' warwick.ac.uk
Web: http://warwick.ac.uk/tenichols
Blog: Neuroimaging Tips & Tricks

[Book Cover]


Handbook of fMRI Data Analysis by Russ Poldrack, Thomas Nichols and Jeanette Mumford