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James Griffin

I am a first year PhD student at the Department of Statistics working under the supervision of Prof Jane Hutton (Statistics) and Dr Ranjit Lall (Warwick Clinical Trials Unit). I am funded by an EPSRC Doctoral Training Account studentship. My research is focussed on the statistical modelling of skewed semi-continuous data in randomised controlled trials (RCTs) with applications of two-part models in RCTs of chronic pain.

Prior to my PhD I worked for three years as a Medical Statistician within Warwick Clinical Trials Unit. I have been the trial statistician for multiple studies in the areas of trauma, rehabilitation, end of life care and mental health (FixDT, FASHIoN ,MILESTONE, RESPECT, I-WOTCH, FIS). In addition I have collaborated with other academics in the unit and at the local teaching hospital, organised conferences and workshops internally and externally. I am employed at Warwick CTU on a part time basis (20% FTE).

Before joining Warwick I worked as a Statistician/Epidemiologist at The Institute of Cancer Research, London where I worked on epidemiological studies of breast cancer in women and men; including a cohort study of over 100,000 women in the UK.

I have an MSc in Medical Statistics from the London School of Hygiene and Medicine and an undergraduate degree in Mathematics, Operational Research, Statistics and Economics from The University of Warwick.

Selected Publications

(Full list of publications)

Journal articles

  • Costa ML, Achten J, Griffin JM, et al. Locking plate fixation versus intramedullary nail fixation for adult patients with a displaced fracture of the distal tibia: a randomised controlled trial (UK FixDT). Journal of American Medical Association, Nov 2017.
  • Singh SP, Tuomainen H, Warwick J, Griffin JM, et al. Protocol for a Cohort Study of adolescent mental health service users with a nested cluster-randomised controlled trial to assess the clinical and cost-effectiveness of managed transition in improving transition from child to mental health services (the MILESTONE study). BMJ Open, Oct 2017.
  • Signorini G, Warwick J, Griffin JM, et al. Architecture, Functioning and Transitional Care Interfaces of Child and Adolescent Menthal Health Services: A European 28 Country Survery. The Lancet Psychiatry, Jun 2017.

Commissioned Reports

  • Ellard DR, Underwood M, Achana F…,Griffin JM, et al.Facet joint injections for people with persistent non-specific low back pain (Facet Injection Study): a feasibility study for a randomised controlled trial. Health Technology Assessment 2017;21(30).
  • Costa ML, Achten J, Hennings S, Boota N, Griffin JM, Petrou S, Maredza M, Dritsaki M, Wood T, Masters J, Pallister I, Lamb SE, Parsons NR.Fixation of Distal Tibia Fractures (UK FixDT): a randomised controlled trial and economic evaluation of ‘locking’ plate fixation versus intramedullary nail fixation in the treatment of patients with a displaced fracture of the distal tibia. Health Technology Assessment

Posters and Presentations

  • "Comparison and impact of prospective and retrospective falls data completion methods in the PreFIT trial: Results of a randomised methodology Study Within A Trial (SWAT)". Joint Meeting of Society of Clinical Trials & International Clinical Trials Methodology Conference 2017, Liverpool, UK
  • “Statistical modelling of skewed data using transformations and two-part models in a large clinical trial of back pain”. International Society of Clinical Biostatistics Conference 2016, Birmingham, UK


  • "Data Management & Statistical Considerations". Chief Investigators Course (January 2015, 2016, 2017) Warwick CTU
  • Student mentorship of postgraduate medical students (SSC2) for final year projects (2016)
  • ‘Stats for the Uninitiated". Warwick CTU Learning Club, 2016
  • “Design and Analysis of Complex (multi-component) Interventions in Clinical trials”. Workshop Facilitator. International Clinical Trials Methodology Conference 2015, Glasgow, UK


  • Member of Staff Student Liaison Committee, 1st year representative
  • Independent statistician for two large NIHR funded trials (BASIL-2 and BASIL-3)
  • Expert reviewer in Statistics, NIHR HTA
  • Journal article reviewer for Trials and Quality of Life Research.


Office: Room C1.03, Dept of Statistics, Zeeman Building