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Department of Chemistry

Dr. Christophe Corre

Associate Professor (Chemistry and Life Sciences)

Bacterial signaling: new chemical keys to unlock the production of novel microbial antibiotics.

  • Understanding the transcriptional regulation of antibiotic biosynthesis in actinomycete bacteria, from which more than 70% of clinically-approved antibiotics originate.
  • Exploiting signaling molecules (microbial hormones) to induce production of novel antibiotics in the laboratory environment

c dot corre at warwick dot ac dot uk

02476 5 23557

Office D0.26 / C5.19

Corre Laboratory

Groups at Warwick

I am working on the following projects at the moment:

  • Project number 1
  • Project number 2
  • Project number 3

I am currently interested in bacterial signalling - new chemical keys to unlock the production of novel microbial antibiotics; understanding the transcriptional regulation of antibiotic biosynthesis in actinomycete bacteria (from which more than 70% of clinically-approved antibiotics originate); exploiting signalling molecules (microbial hormones) to induce production of novel antibiotics in the laboratory environment.

Christophe teaches...

I am supervising the following PhD students:

  • Person 1, Topic 1
  • Person 2, Topic 2
  • Person 3, Topic 3

At the moment I am unable to accept any further applications, but if you get in touch I'll see if a member of my team might be able to help.

J.D. Sidda, L. Song, V. Poon, M. Al-Bassam, O. Lazos, M.J. Buttner, G.L. Challis and C. Corre. Chem. Sci., 2014, 5, 86-89.
 
P.K. Sydor, S. M. Barry, O.M. Odulate, F. Barona-Gomez, S.W. Haynes, C. Corre, L. Song, and G.L. Challis. Nat. Chem., 2011, 3, 388-392.
L. Laureti, L. Song, S. Huang, C. Corre, P. Leblond, G.L. Challis and B. Aigle, Proc. Natl Acad. Sci. USA, 2011, 108, 6258-6263.
2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining
C. Corre, L. Song, S. O'Rourke, K.F. Chater, G.L. Challis. Proc. Nat. Acad. Sci. USA. 2008, 105, 17510-17515.